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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PUS7
Full Name:
Pseudouridylate synthase 7 homolog
Alias:
EC 5.4.99.-; FLJ20485; K1897; KIAA1897; Pseudouridylate synthase 7
Type:
Isomerase; EC 5.4.99.-
Mass (Da):
75035
Number AA:
661
UniProt ID:
Q96PZ0
International Prot ID:
IPI00044761
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003723
GO:0003824
PhosphoSite+
KinaseNET
Biological Process:
GO:0001522
GO:0006139
GO:0006396
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
L
V
V
E
D
N
D
S
G
V
P
V
E
E
T
Site 2
S36
E
T
K
K
Q
K
L
S
E
C
S
L
T
K
G
Site 3
S39
K
Q
K
L
S
E
C
S
L
T
K
G
Q
D
G
Site 4
T41
K
L
S
E
C
S
L
T
K
G
Q
D
G
L
Q
Site 5
S53
G
L
Q
N
D
F
L
S
I
S
E
D
V
P
R
Site 6
S55
Q
N
D
F
L
S
I
S
E
D
V
P
R
P
P
Site 7
T64
D
V
P
R
P
P
D
T
V
S
T
G
K
G
G
Site 8
S66
P
R
P
P
D
T
V
S
T
G
K
G
G
K
N
Site 9
S90
E
E
E
E
D
G
L
S
E
E
C
E
E
E
E
Site 10
S98
E
E
C
E
E
E
E
S
E
S
F
A
D
M
M
Site 11
S100
C
E
E
E
E
S
E
S
F
A
D
M
M
K
H
Site 12
T117
T
E
A
D
V
G
I
T
K
F
V
S
S
H
Q
Site 13
S121
V
G
I
T
K
F
V
S
S
H
Q
G
F
S
G
Site 14
Y134
S
G
I
L
K
E
R
Y
S
D
F
V
V
H
E
Site 15
S135
G
I
L
K
E
R
Y
S
D
F
V
V
H
E
I
Site 16
S149
I
G
K
D
G
R
I
S
H
L
N
D
L
S
I
Site 17
S155
I
S
H
L
N
D
L
S
I
P
V
D
E
E
D
Site 18
S164
P
V
D
E
E
D
P
S
E
D
I
F
T
V
L
Site 19
T169
D
P
S
E
D
I
F
T
V
L
T
A
E
E
K
Site 20
S213
I
I
H
Q
A
I
K
S
L
F
P
G
L
E
T
Site 21
T222
F
P
G
L
E
T
K
T
E
D
R
E
G
K
K
Site 22
Y230
E
D
R
E
G
K
K
Y
I
V
A
Y
H
A
A
Site 23
Y234
G
K
K
Y
I
V
A
Y
H
A
A
G
K
K
A
Site 24
S249
L
A
N
P
R
K
H
S
W
P
K
S
R
G
S
Site 25
Y257
W
P
K
S
R
G
S
Y
C
H
F
V
L
Y
K
Site 26
Y263
S
Y
C
H
F
V
L
Y
K
E
N
K
D
T
M
Site 27
T269
L
Y
K
E
N
K
D
T
M
D
A
I
N
V
L
Site 28
Y279
A
I
N
V
L
S
K
Y
L
R
V
K
P
N
I
Site 29
T292
N
I
F
S
Y
M
G
T
K
D
K
R
A
I
T
Site 30
S329
N
F
K
L
G
N
F
S
Y
Q
K
N
P
L
K
Site 31
Y330
F
K
L
G
N
F
S
Y
Q
K
N
P
L
K
L
Site 32
T353
T
V
V
L
R
N
I
T
G
T
D
D
Q
V
Q
Site 33
T355
V
L
R
N
I
T
G
T
D
D
Q
V
Q
Q
A
Site 34
Y374
K
E
I
G
F
I
N
Y
Y
G
M
Q
R
F
G
Site 35
Y375
E
I
G
F
I
N
Y
Y
G
M
Q
R
F
G
T
Site 36
T382
Y
G
M
Q
R
F
G
T
T
A
V
P
T
Y
Q
Site 37
S411
D
L
I
L
K
P
R
S
G
A
E
K
G
Y
L
Site 38
T428
C
R
E
E
W
A
K
T
K
D
P
T
A
A
L
Site 39
S453
G
Q
L
L
R
G
L
S
K
Y
G
M
K
N
I
Site 40
Y475
P
R
N
N
R
L
M
Y
I
H
S
Y
Q
S
Y
Site 41
Y479
R
L
M
Y
I
H
S
Y
Q
S
Y
V
W
N
N
Site 42
Y495
V
S
K
R
I
E
D
Y
G
L
K
P
V
P
G
Site 43
Y538
L
P
G
F
D
V
I
Y
P
K
H
K
I
Q
E
Site 44
Y568
M
R
H
K
I
R
D
Y
S
L
S
G
A
Y
R
Site 45
S569
R
H
K
I
R
D
Y
S
L
S
G
A
Y
R
K
Site 46
S571
K
I
R
D
Y
S
L
S
G
A
Y
R
K
I
I
Site 47
T601
P
K
I
P
L
F
N
T
D
V
D
N
L
E
G
Site 48
T610
V
D
N
L
E
G
K
T
P
P
V
F
A
S
E
Site 49
Y620
V
F
A
S
E
G
K
Y
R
A
L
K
M
D
F
Site 50
S628
R
A
L
K
M
D
F
S
L
P
P
S
T
Y
A
Site 51
S648
E
V
L
K
M
D
T
S
I
K
N
Q
T
Q
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation