KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FLJ22794
Full Name:
Protein FAM111A
Alias:
F111A; FAM111A; Family with sequence similarity 111, member A; KIAA1895; LOC63901
Type:
Unknown function
Mass (Da):
70196
Number AA:
628
UniProt ID:
Q96PZ2
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003824
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
C
K
K
Q
R
S
R
K
H
S
V
N
E
Site 2
S12
K
Q
R
S
R
K
H
S
V
N
E
K
C
N
M
Site 3
Y24
C
N
M
K
I
E
H
Y
F
S
P
V
S
K
E
Site 4
S26
M
K
I
E
H
Y
F
S
P
V
S
K
E
Q
Q
Site 5
S39
Q
Q
N
N
C
S
T
S
L
M
R
M
E
S
R
Site 6
S45
T
S
L
M
R
M
E
S
R
G
D
P
R
A
T
Site 7
T52
S
R
G
D
P
R
A
T
T
N
T
Q
A
Q
R
Site 8
T53
R
G
D
P
R
A
T
T
N
T
Q
A
Q
R
F
Site 9
T55
D
P
R
A
T
T
N
T
Q
A
Q
R
F
H
S
Site 10
S62
T
Q
A
Q
R
F
H
S
P
K
K
N
P
E
D
Site 11
Y79
M
P
Q
N
R
T
I
Y
V
T
L
K
V
N
H
Site 12
T81
Q
N
R
T
I
Y
V
T
L
K
V
N
H
R
R
Site 13
T97
Q
D
M
K
L
K
L
T
H
S
E
N
S
S
L
Site 14
S99
M
K
L
K
L
T
H
S
E
N
S
S
L
Y
M
Site 15
S102
K
L
T
H
S
E
N
S
S
L
Y
M
A
L
N
Site 16
S103
L
T
H
S
E
N
S
S
L
Y
M
A
L
N
T
Site 17
Y105
H
S
E
N
S
S
L
Y
M
A
L
N
T
L
Q
Site 18
T120
A
V
R
K
E
I
E
T
H
Q
G
Q
E
M
L
Site 19
T131
Q
E
M
L
V
R
G
T
E
G
I
K
E
Y
I
Site 20
Y137
G
T
E
G
I
K
E
Y
I
N
L
G
M
P
L
Site 21
T156
E
G
G
Q
V
V
I
T
F
S
Q
S
K
S
K
Site 22
S158
G
Q
V
V
I
T
F
S
Q
S
K
S
K
Q
K
Site 23
S162
I
T
F
S
Q
S
K
S
K
Q
K
E
D
N
H
Site 24
S178
F
G
R
Q
D
K
A
S
T
E
C
V
K
F
Y
Site 25
T179
G
R
Q
D
K
A
S
T
E
C
V
K
F
Y
I
Site 26
Y214
K
G
R
K
L
C
V
Y
A
F
K
G
E
T
I
Site 27
S233
C
K
D
G
R
F
L
S
F
L
E
N
D
D
W
Site 28
T248
K
L
I
E
N
N
D
T
I
L
E
S
T
Q
P
Site 29
Y263
V
D
E
L
E
G
R
Y
F
Q
V
E
V
E
K
Site 30
S275
V
E
K
R
M
V
P
S
A
A
A
S
Q
N
P
Site 31
S279
M
V
P
S
A
A
A
S
Q
N
P
E
S
E
K
Site 32
S284
A
A
S
Q
N
P
E
S
E
K
R
N
T
C
V
Site 33
T289
P
E
S
E
K
R
N
T
C
V
L
R
E
Q
I
Site 34
Y300
R
E
Q
I
V
A
Q
Y
P
S
L
K
R
E
S
Site 35
S302
Q
I
V
A
Q
Y
P
S
L
K
R
E
S
E
K
Site 36
S307
Y
P
S
L
K
R
E
S
E
K
I
I
E
N
F
Site 37
T332
T
L
F
E
L
H
R
T
T
F
G
K
V
T
K
Site 38
T333
L
F
E
L
H
R
T
T
F
G
K
V
T
K
N
Site 39
T338
R
T
T
F
G
K
V
T
K
N
S
S
S
I
K
Site 40
S341
F
G
K
V
T
K
N
S
S
S
I
K
V
V
K
Site 41
S342
G
K
V
T
K
N
S
S
S
I
K
V
V
K
L
Site 42
S343
K
V
T
K
N
S
S
S
I
K
V
V
K
L
L
Site 43
T411
I
G
Q
C
V
R
V
T
F
G
Y
E
E
L
K
Site 44
Y414
C
V
R
V
T
F
G
Y
E
E
L
K
D
K
E
Site 45
T422
E
E
L
K
D
K
E
T
N
Y
F
F
V
E
P
Site 46
Y424
L
K
D
K
E
T
N
Y
F
F
V
E
P
W
F
Site 47
Y440
I
H
N
E
E
L
D
Y
A
V
L
K
L
K
E
Site 48
Y457
Q
Q
V
P
M
E
L
Y
N
G
I
T
P
V
P
Site 49
S503
K
C
Q
E
R
V
Q
S
K
K
A
E
S
P
E
Site 50
S508
V
Q
S
K
K
A
E
S
P
E
Y
V
H
M
Y
Site 51
Y511
K
K
A
E
S
P
E
Y
V
H
M
Y
T
Q
R
Site 52
Y515
S
P
E
Y
V
H
M
Y
T
Q
R
S
F
Q
K
Site 53
Y532
H
N
P
D
V
I
T
Y
D
T
E
F
F
F
G
Site 54
Y564
A
A
G
F
A
Y
T
Y
Q
N
E
T
R
S
I
Site 55
T568
A
Y
T
Y
Q
N
E
T
R
S
I
I
E
F
G
Site 56
S580
E
F
G
S
T
M
E
S
I
L
L
D
I
K
Q
Site 57
Y593
K
Q
R
H
K
P
W
Y
E
E
V
F
V
N
Q
Site 58
S607
Q
Q
D
V
E
M
M
S
D
E
D
L
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation