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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ASB2
Full Name:
Ankyrin repeat and SOCS box protein 2
Alias:
Type:
Mass (Da):
65084
Number AA:
587
UniProt ID:
Q96Q27
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
T
R
F
S
Y
A
E
Y
F
S
L
F
H
S
C
Site 2
S15
E
Y
F
S
L
F
H
S
C
S
A
P
S
R
S
Site 3
S17
F
S
L
F
H
S
C
S
A
P
S
R
S
T
A
Site 4
S22
S
C
S
A
P
S
R
S
T
A
P
P
E
S
S
Site 5
T23
C
S
A
P
S
R
S
T
A
P
P
E
S
S
P
Site 6
S28
R
S
T
A
P
P
E
S
S
P
A
R
A
P
M
Site 7
S29
S
T
A
P
P
E
S
S
P
A
R
A
P
M
G
Site 8
Y45
F
Q
G
V
M
Q
K
Y
S
S
S
L
F
K
T
Site 9
S46
Q
G
V
M
Q
K
Y
S
S
S
L
F
K
T
S
Site 10
S48
V
M
Q
K
Y
S
S
S
L
F
K
T
S
Q
L
Site 11
T52
Y
S
S
S
L
F
K
T
S
Q
L
A
P
A
D
Site 12
T75
G
D
E
E
A
L
K
T
M
I
K
E
G
K
N
Site 13
Y100
P
L
H
E
A
A
Y
Y
G
Q
V
G
C
L
K
Site 14
Y113
L
K
V
L
Q
R
A
Y
P
G
T
I
D
Q
R
Site 15
T116
L
Q
R
A
Y
P
G
T
I
D
Q
R
T
L
Q
Site 16
T121
P
G
T
I
D
Q
R
T
L
Q
E
E
T
A
V
Site 17
Y129
L
Q
E
E
T
A
V
Y
L
A
T
C
R
G
H
Site 18
S153
A
G
A
E
P
D
I
S
N
K
S
R
E
T
P
Site 19
S156
E
P
D
I
S
N
K
S
R
E
T
P
L
Y
K
Site 20
T159
I
S
N
K
S
R
E
T
P
L
Y
K
A
C
E
Site 21
Y162
K
S
R
E
T
P
L
Y
K
A
C
E
R
K
N
Site 22
T192
H
R
C
N
R
G
W
T
A
L
H
E
S
V
S
Site 23
S197
G
W
T
A
L
H
E
S
V
S
R
N
D
L
E
Site 24
S199
T
A
L
H
E
S
V
S
R
N
D
L
E
V
M
Site 25
S218
S
G
G
A
K
V
E
S
K
N
A
Y
G
I
T
Site 26
Y245
A
L
R
F
L
A
K
Y
G
A
D
I
N
T
Q
Site 27
T251
K
Y
G
A
D
I
N
T
Q
A
S
D
N
A
S
Site 28
S254
A
D
I
N
T
Q
A
S
D
N
A
S
A
L
Y
Site 29
S258
T
Q
A
S
D
N
A
S
A
L
Y
E
A
C
K
Site 30
Y261
S
D
N
A
S
A
L
Y
E
A
C
K
N
E
H
Site 31
S277
E
V
V
E
F
L
L
S
Q
G
A
D
A
N
K
Site 32
T285
Q
G
A
D
A
N
K
T
N
K
D
G
L
L
P
Site 33
T312
V
Q
M
L
L
P
V
T
S
R
T
R
I
R
R
Site 34
S313
Q
M
L
L
P
V
T
S
R
T
R
I
R
R
S
Site 35
S320
S
R
T
R
I
R
R
S
G
V
S
P
L
H
L
Site 36
S323
R
I
R
R
S
G
V
S
P
L
H
L
A
A
E
Site 37
T349
S
A
R
F
D
V
N
T
P
L
A
P
E
R
A
Site 38
Y359
A
P
E
R
A
R
L
Y
E
D
R
R
S
S
A
Site 39
S364
R
L
Y
E
D
R
R
S
S
A
L
Y
F
A
V
Site 40
Y368
D
R
R
S
S
A
L
Y
F
A
V
V
N
N
N
Site 41
Y422
H
G
A
N
I
D
A
Y
I
A
T
H
P
T
A
Site 42
Y462
E
P
C
F
S
C
L
Y
G
N
G
P
H
P
P
Site 43
S474
H
P
P
A
P
Q
P
S
S
R
F
N
D
A
P
Site 44
S475
P
P
A
P
Q
P
S
S
R
F
N
D
A
P
A
Site 45
S488
P
A
A
D
K
E
P
S
V
V
Q
F
C
E
F
Site 46
S523
V
G
N
V
Q
L
C
S
R
L
K
E
H
I
D
Site 47
S531
R
L
K
E
H
I
D
S
F
E
D
W
A
V
I
Site 48
Y580
L
P
G
R
L
I
R
Y
L
K
Y
E
N
T
Q
Site 49
Y583
R
L
I
R
Y
L
K
Y
E
N
T
Q
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation