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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ALKBH3
Full Name:
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3
Alias:
AlkB, alkylation repair 3; AlkB, alkylation repair homolog 3 (E. coli); ALKB3; DEPC1; DEPC-1; Prostate cancer antigen-1
Type:
EC 1.14.11.-; Hydrolase; Demethylase; Oxidoreductase
Mass (Da):
33370
Number AA:
UniProt ID:
Q96Q83
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005654
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0031418
GO:0003684
GO:0005506
PhosphoSite+
KinaseNET
Biological Process:
GO:0006281
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T28
Q
A
I
A
Q
P
A
T
T
A
K
S
H
L
H
Site 2
S32
Q
P
A
T
T
A
K
S
H
L
H
Q
K
P
G
Site 3
S50
K
N
K
E
H
H
L
S
D
R
E
F
V
F
K
Site 4
Y78
V
I
D
R
E
G
V
Y
E
I
S
L
S
P
T
Site 5
S81
R
E
G
V
Y
E
I
S
L
S
P
T
G
V
S
Site 6
T126
T
G
I
R
E
D
I
T
Y
Q
Q
P
R
L
T
Site 7
Y127
G
I
R
E
D
I
T
Y
Q
Q
P
R
L
T
A
Site 8
T133
T
Y
Q
Q
P
R
L
T
A
W
Y
G
E
L
P
Site 9
Y136
Q
P
R
L
T
A
W
Y
G
E
L
P
Y
T
Y
Site 10
Y143
Y
G
E
L
P
Y
T
Y
S
R
I
T
M
E
P
Site 11
S144
G
E
L
P
Y
T
Y
S
R
I
T
M
E
P
N
Site 12
T169
K
N
R
I
E
E
N
T
G
H
T
F
N
S
L
Site 13
T172
I
E
E
N
T
G
H
T
F
N
S
L
L
C
N
Site 14
Y181
N
S
L
L
C
N
L
Y
R
N
E
K
D
S
V
Site 15
S187
L
Y
R
N
E
K
D
S
V
D
W
H
S
D
D
Site 16
S192
K
D
S
V
D
W
H
S
D
D
E
P
S
L
G
Site 17
S197
W
H
S
D
D
E
P
S
L
G
R
C
P
I
I
Site 18
T212
A
S
L
S
F
G
A
T
R
T
F
E
M
R
K
Site 19
T214
L
S
F
G
A
T
R
T
F
E
M
R
K
K
P
Site 20
Y229
P
P
E
E
N
G
D
Y
T
Y
V
E
R
V
K
Site 21
T230
P
E
E
N
G
D
Y
T
Y
V
E
R
V
K
I
Site 22
Y231
E
E
N
G
D
Y
T
Y
V
E
R
V
K
I
P
Site 23
Y263
Q
H
R
V
P
K
E
Y
H
S
R
E
P
R
V
Site 24
T273
R
E
P
R
V
N
L
T
F
R
T
V
Y
P
D
Site 25
T276
R
V
N
L
T
F
R
T
V
Y
P
D
P
R
G
Site 26
Y278
N
L
T
F
R
T
V
Y
P
D
P
R
G
A
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation