PhosphoNET

           
Protein Info 
   
Short Name:  GSDMA
Full Name:  Gasdermin-A
Alias:  Gasdermin family member A; GSDM; GSDM1
Type:  Apoptosis protein; Cytoplasm
Mass (Da):  49379
Number AA:  445
UniProt ID:  Q96QA5
International Prot ID:  IPI00166200
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T22LNPRGDLTPLDSLID
Site 2S26GDLTPLDSLIDFKRF
Site 3S45LVLRKRKSTLFWGAR
Site 4T46VLRKRKSTLFWGARY
Site 5Y53TLFWGARYVRTDYTL
Site 6Y58ARYVRTDYTLLDVLE
Site 7T59RYVRTDYTLLDVLEP
Site 8S68LDVLEPGSSPSDPTD
Site 9S69DVLEPGSSPSDPTDT
Site 10S71LEPGSSPSDPTDTGN
Site 11T74GSSPSDPTDTGNFGF
Site 12T76SPSDPTDTGNFGFKN
Site 13T98GDVDVPKTVKVKGTA
Site 14S108VKGTAGLSQNSTLEV
Site 15T112AGLSQNSTLEVQTLS
Site 16Y151QDQGENLYVVMEVVE
Site 17S188APLGLQGSINHKEAV
Site 18T196INHKEAVTIPKGCVL
Site 19T230ICNDNMQTFPPGEKS
Site 20S237TFPPGEKSGEEKVIL
Site 21T259DVHEGFRTLKEEVQR
Site 22T268KEEVQRETQQVEKLS
Site 23S275TQQVEKLSRVGQSSL
Site 24S280KLSRVGQSSLLSSLS
Site 25S281LSRVGQSSLLSSLSK
Site 26S285GQSSLLSSLSKLLGK
Site 27S287SSLLSSLSKLLGKKK
Site 28S353QQKLLVKSMEKKILP
Site 29S391LQPELLSSLGDEELT
Site 30S414SGLEVQRSGPQYMWD
Site 31Y418VQRSGPQYMWDPDTL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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