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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DEPDC7
Full Name:
DEP domain-containing protein 7
Alias:
DEP domain containing 7; DEPD7
Type:
Unknown function
Mass (Da):
58310
Number AA:
UniProt ID:
Q96QD5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007242
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
L
N
L
S
A
L
H
S
P
A
H
R
P
P
G
Site 2
S27
A
H
R
P
P
G
F
S
V
A
Q
K
P
F
G
Site 3
Y37
Q
K
P
F
G
A
T
Y
V
W
S
S
I
I
N
Site 4
Y84
S
H
L
I
Q
N
K
Y
F
G
D
V
D
I
P
Site 5
T113
K
V
F
E
A
V
P
T
K
V
F
G
K
D
K
Site 6
T123
F
G
K
D
K
K
P
T
F
E
D
S
S
C
S
Site 7
S127
K
K
P
T
F
E
D
S
S
C
S
L
Y
R
F
Site 8
S128
K
P
T
F
E
D
S
S
C
S
L
Y
R
F
T
Site 9
S130
T
F
E
D
S
S
C
S
L
Y
R
F
T
T
I
Site 10
Y132
E
D
S
S
C
S
L
Y
R
F
T
T
I
P
N
Site 11
T135
S
C
S
L
Y
R
F
T
T
I
P
N
Q
D
S
Site 12
T136
C
S
L
Y
R
F
T
T
I
P
N
Q
D
S
Q
Site 13
S142
T
T
I
P
N
Q
D
S
Q
L
G
K
E
N
K
Site 14
Y151
L
G
K
E
N
K
L
Y
S
P
A
R
Y
A
D
Site 15
S152
G
K
E
N
K
L
Y
S
P
A
R
Y
A
D
A
Site 16
Y156
K
L
Y
S
P
A
R
Y
A
D
A
L
F
K
S
Site 17
S163
Y
A
D
A
L
F
K
S
S
D
I
R
S
A
S
Site 18
S164
A
D
A
L
F
K
S
S
D
I
R
S
A
S
L
Site 19
S168
F
K
S
S
D
I
R
S
A
S
L
E
D
L
W
Site 20
S170
S
S
D
I
R
S
A
S
L
E
D
L
W
E
N
Site 21
S179
E
D
L
W
E
N
L
S
L
K
P
A
N
S
P
Site 22
S185
L
S
L
K
P
A
N
S
P
H
V
N
I
S
A
Site 23
S191
N
S
P
H
V
N
I
S
A
T
L
S
P
Q
V
Site 24
S222
V
D
L
P
L
L
D
S
L
L
K
Q
Q
E
A
Site 25
S240
I
P
Q
P
K
R
Q
S
T
M
V
N
S
S
N
Site 26
T241
P
Q
P
K
R
Q
S
T
M
V
N
S
S
N
Y
Site 27
Y248
T
M
V
N
S
S
N
Y
L
D
R
G
I
L
K
Site 28
S258
R
G
I
L
K
A
Y
S
D
S
Q
E
D
E
W
Site 29
S260
I
L
K
A
Y
S
D
S
Q
E
D
E
W
L
S
Site 30
S287
M
V
V
E
I
S
R
S
F
P
E
Q
P
D
R
Site 31
T295
F
P
E
Q
P
D
R
T
D
L
V
K
E
L
L
Site 32
Y309
L
F
D
A
I
G
R
Y
Y
S
S
R
E
P
L
Site 33
Y310
F
D
A
I
G
R
Y
Y
S
S
R
E
P
L
L
Site 34
S311
D
A
I
G
R
Y
Y
S
S
R
E
P
L
L
N
Site 35
S312
A
I
G
R
Y
Y
S
S
R
E
P
L
L
N
H
Site 36
S321
E
P
L
L
N
H
L
S
D
V
H
N
G
I
A
Site 37
T336
E
L
L
V
N
G
K
T
E
I
A
L
E
A
T
Site 38
Y449
D
P
N
R
D
A
G
Y
I
Y
C
Q
R
I
D
Site 39
Y451
N
R
D
A
G
Y
I
Y
C
Q
R
I
D
Q
R
Site 40
Y460
Q
R
I
D
Q
R
D
Y
S
N
N
T
E
K
T
Site 41
S461
R
I
D
Q
R
D
Y
S
N
N
T
E
K
T
T
Site 42
T478
E
L
L
N
L
L
K
T
L
D
E
D
S
K
L
Site 43
S483
L
K
T
L
D
E
D
S
K
L
S
A
K
E
K
Site 44
Y498
K
K
L
L
G
Q
F
Y
K
C
H
P
D
I
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation