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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARX
Full Name:
Homeobox protein ARX
Alias:
Aristaless-related homeobox
Type:
Mass (Da):
58160
Number AA:
562
UniProt ID:
Q96QS3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
Q
Y
Q
E
E
G
C
S
E
R
P
E
C
K
S
Site 2
S18
S
E
R
P
E
C
K
S
K
S
P
T
L
L
S
Site 3
S20
R
P
E
C
K
S
K
S
P
T
L
L
S
S
Y
Site 4
T22
E
C
K
S
K
S
P
T
L
L
S
S
Y
C
I
Site 5
S25
S
K
S
P
T
L
L
S
S
Y
C
I
D
S
I
Site 6
S31
L
S
S
Y
C
I
D
S
I
L
G
R
R
S
P
Site 7
S37
D
S
I
L
G
R
R
S
P
C
K
M
R
L
L
Site 8
T55
Q
S
L
P
A
P
L
T
S
R
A
D
P
E
K
Site 9
S67
P
E
K
A
V
Q
G
S
P
K
S
S
S
A
P
Site 10
S70
A
V
Q
G
S
P
K
S
S
S
A
P
F
E
A
Site 11
S71
V
Q
G
S
P
K
S
S
S
A
P
F
E
A
E
Site 12
S72
Q
G
S
P
K
S
S
S
A
P
F
E
A
E
L
Site 13
Y89
P
P
K
L
R
R
L
Y
G
P
G
G
G
R
L
Site 14
T132
A
P
P
P
P
P
P
T
A
R
P
G
E
R
P
Site 15
S162
A
W
D
T
L
K
I
S
Q
A
P
Q
V
S
I
Site 16
S168
I
S
Q
A
P
Q
V
S
I
S
R
S
K
S
Y
Site 17
S170
Q
A
P
Q
V
S
I
S
R
S
K
S
Y
R
E
Site 18
S172
P
Q
V
S
I
S
R
S
K
S
Y
R
E
N
G
Site 19
S174
V
S
I
S
R
S
K
S
Y
R
E
N
G
A
P
Site 20
S290
A
T
E
G
G
E
L
S
P
K
E
E
L
L
L
Site 21
S310
E
G
K
D
G
E
D
S
V
C
L
S
A
G
S
Site 22
S314
G
E
D
S
V
C
L
S
A
G
S
D
S
E
E
Site 23
S319
C
L
S
A
G
S
D
S
E
E
G
L
L
K
R
Site 24
Y331
L
K
R
K
Q
R
R
Y
R
T
T
F
T
S
Y
Site 25
T333
R
K
Q
R
R
Y
R
T
T
F
T
S
Y
Q
L
Site 26
T334
K
Q
R
R
Y
R
T
T
F
T
S
Y
Q
L
E
Site 27
S337
R
Y
R
T
T
F
T
S
Y
Q
L
E
E
L
E
Site 28
T350
L
E
R
A
F
Q
K
T
H
Y
P
D
V
F
T
Site 29
Y352
R
A
F
Q
K
T
H
Y
P
D
V
F
T
R
E
Site 30
T393
R
E
K
A
G
A
Q
T
H
P
P
G
L
P
F
Site 31
S405
L
P
F
P
G
P
L
S
A
T
H
P
L
S
P
Site 32
S411
L
S
A
T
H
P
L
S
P
Y
L
D
A
S
P
Site 33
Y413
A
T
H
P
L
S
P
Y
L
D
A
S
P
F
P
Site 34
S417
L
S
P
Y
L
D
A
S
P
F
P
P
H
H
P
Site 35
S428
P
H
H
P
A
L
D
S
A
W
T
A
A
A
A
Site 36
S450
S
L
P
P
P
P
G
S
A
S
L
P
P
S
G
Site 37
S452
P
P
P
P
G
S
A
S
L
P
P
S
G
A
P
Site 38
S486
P
A
F
G
R
L
F
S
T
M
A
P
L
T
S
Site 39
T522
G
A
L
A
D
P
A
T
A
A
A
D
R
R
A
Site 40
S531
A
A
D
R
R
A
S
S
I
A
A
L
R
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation