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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
XPO6
Full Name:
Exportin-6
Alias:
Exportin 6; Exportin-6: Ran-binding protein 20; FLJ22519; KIAA0370; Ran binding protein RanBP20; RANBP20
Type:
Mass (Da):
128883
Number AA:
1125
UniProt ID:
Q96QU8
International Prot ID:
IPI00465296
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008565
PhosphoSite+
KinaseNET
Biological Process:
GO:0006611
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
S
E
E
A
S
L
R
A
L
E
S
L
Site 2
T16
R
A
L
E
S
L
M
T
E
F
F
H
D
C
T
Site 3
Y50
G
A
W
R
F
C
L
Y
F
L
S
S
T
R
N
Site 4
Y59
L
S
S
T
R
N
D
Y
V
M
M
Y
S
L
T
Site 5
S81
K
M
W
L
G
V
P
S
Q
D
K
M
E
I
R
Site 6
Y104
A
H
H
K
T
L
P
Y
F
I
R
N
K
L
C
Site 7
T152
L
G
L
I
M
L
K
T
T
S
E
E
L
A
C
Site 8
T153
G
L
I
M
L
K
T
T
S
E
E
L
A
C
P
Site 9
S154
L
I
M
L
K
T
T
S
E
E
L
A
C
P
R
Site 10
S165
A
C
P
R
E
D
L
S
V
A
R
K
E
E
L
Site 11
S199
E
T
V
W
D
K
H
S
V
T
A
A
T
P
P
Site 12
T201
V
W
D
K
H
S
V
T
A
A
T
P
P
P
S
Site 13
T204
K
H
S
V
T
A
A
T
P
P
P
S
P
T
S
Site 14
S208
T
A
A
T
P
P
P
S
P
T
S
G
E
S
G
Site 15
T210
A
T
P
P
P
S
P
T
S
G
E
S
G
D
L
Site 16
S211
T
P
P
P
S
P
T
S
G
E
S
G
D
L
L
Site 17
S214
P
S
P
T
S
G
E
S
G
D
L
L
S
N
L
Site 18
S219
G
E
S
G
D
L
L
S
N
L
L
Q
S
P
S
Site 19
S224
L
L
S
N
L
L
Q
S
P
S
S
A
K
L
L
Site 20
S226
S
N
L
L
Q
S
P
S
S
A
K
L
L
N
Q
Site 21
S227
N
L
L
Q
S
P
S
S
A
K
L
L
N
Q
P
Site 22
S291
I
R
A
R
K
M
A
S
V
N
G
S
S
Q
N
Site 23
S295
K
M
A
S
V
N
G
S
S
Q
N
C
V
S
G
Site 24
S296
M
A
S
V
N
G
S
S
Q
N
C
V
S
G
Q
Site 25
Y332
V
P
M
E
F
E
E
Y
L
L
R
M
F
Q
Q
Site 26
Y342
R
M
F
Q
Q
T
F
Y
L
L
Q
K
I
T
K
Site 27
T355
T
K
D
N
N
A
H
T
V
K
S
R
L
E
E
Site 28
S358
N
N
A
H
T
V
K
S
R
L
E
E
L
D
E
Site 29
S366
R
L
E
E
L
D
E
S
Y
I
E
K
F
T
D
Site 30
Y367
L
E
E
L
D
E
S
Y
I
E
K
F
T
D
F
Site 31
S388
V
H
L
R
R
I
E
S
Y
S
Q
F
P
V
V
Site 32
S390
L
R
R
I
E
S
Y
S
Q
F
P
V
V
E
F
Site 33
T405
L
T
L
L
F
K
Y
T
F
H
Q
P
T
H
E
Site 34
S434
Y
L
T
S
K
I
K
S
R
L
G
D
K
E
A
Site 35
Y465
L
N
R
I
Q
F
R
Y
N
Q
A
Q
L
E
E
Site 36
T477
L
E
E
L
D
D
E
T
L
D
D
D
Q
Q
T
Site 37
T484
T
L
D
D
D
Q
Q
T
E
W
Q
R
Y
L
R
Site 38
Y489
Q
Q
T
E
W
Q
R
Y
L
R
Q
S
L
E
V
Site 39
S493
W
Q
R
Y
L
R
Q
S
L
E
V
V
A
K
V
Site 40
S535
Q
F
I
V
T
S
G
S
G
H
R
L
N
I
T
Site 41
T542
S
G
H
R
L
N
I
T
A
E
N
D
C
R
R
Site 42
S553
D
C
R
R
L
H
C
S
L
R
D
L
S
S
L
Site 43
T585
A
R
F
N
D
A
L
T
V
V
E
R
L
V
K
Site 44
Y603
Y
G
S
Q
I
K
L
Y
N
I
E
T
A
V
P
Site 45
T647
S
E
V
H
R
Q
N
T
Q
Q
F
V
T
L
I
Site 46
T652
Q
N
T
Q
Q
F
V
T
L
I
S
T
T
M
D
Site 47
S655
Q
Q
F
V
T
L
I
S
T
T
M
D
A
I
T
Site 48
T707
Q
K
V
F
N
R
I
T
D
A
S
A
L
R
L
Site 49
S710
F
N
R
I
T
D
A
S
A
L
R
L
V
D
K
Site 50
S759
A
S
L
I
S
A
L
S
R
D
Y
R
N
L
K
Site 51
Y762
I
S
A
L
S
R
D
Y
R
N
L
K
P
S
A
Site 52
S768
D
Y
R
N
L
K
P
S
A
V
A
P
Q
R
K
Site 53
T781
R
K
M
P
L
D
D
T
K
L
I
I
H
Q
T
Site 54
T788
T
K
L
I
I
H
Q
T
L
S
V
L
E
D
I
Site 55
T804
E
N
I
S
G
E
S
T
K
S
R
Q
I
C
Y
Site 56
S806
I
S
G
E
S
T
K
S
R
Q
I
C
Y
Q
S
Site 57
Y811
T
K
S
R
Q
I
C
Y
Q
S
L
Q
E
S
V
Site 58
S813
S
R
Q
I
C
Y
Q
S
L
Q
E
S
V
Q
V
Site 59
T884
S
I
L
H
E
G
S
T
G
C
R
V
V
E
K
Site 60
S931
P
I
I
A
E
R
P
S
P
D
V
K
A
E
L
Site 61
T957
W
R
Y
F
F
K
S
T
V
L
A
S
V
Q
R
Site 62
S961
F
K
S
T
V
L
A
S
V
Q
R
G
I
A
E
Site 63
Y1002
L
F
K
Q
N
L
F
Y
L
E
T
L
N
T
K
Site 64
T1005
Q
N
L
F
Y
L
E
T
L
N
T
K
Q
K
L
Site 65
T1008
F
Y
L
E
T
L
N
T
K
Q
K
L
Y
H
K
Site 66
S1038
L
Q
V
L
V
H
K
S
H
D
L
L
Q
E
E
Site 67
S1082
G
V
D
A
N
Q
K
S
V
L
G
R
N
F
K
Site 68
S1096
K
M
D
R
D
L
P
S
F
T
Q
N
V
H
R
Site 69
Y1110
R
L
V
N
D
L
R
Y
Y
R
L
C
N
D
S
Site 70
Y1111
L
V
N
D
L
R
Y
Y
R
L
C
N
D
S
L
Site 71
S1117
Y
Y
R
L
C
N
D
S
L
P
P
G
T
V
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation