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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PANX1
Full Name:
Pannexin-1
Alias:
Innexin; MRS1; Pannexin 1; PX1; UNQ2529
Type:
Adhesion
Mass (Da):
48059
Number AA:
426
UniProt ID:
Q96RD7
International Prot ID:
Isoform1 - IPI00455165
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0032059
GO:0005921
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005102
PhosphoSite+
KinaseNET
Biological Process:
GO:0006812
GO:0050718
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
D
F
L
L
K
E
P
T
E
P
K
F
K
G
L
Site 2
S68
G
T
Q
I
S
C
F
S
P
S
S
F
S
W
R
Site 3
S70
Q
I
S
C
F
S
P
S
S
F
S
W
R
Q
A
Site 4
S71
I
S
C
F
S
P
S
S
F
S
W
R
Q
A
A
Site 5
S93
A
A
V
Q
Q
K
N
S
L
Q
S
E
S
G
N
Site 6
S96
Q
Q
K
N
S
L
Q
S
E
S
G
N
L
P
L
Site 7
Y150
M
E
E
L
D
K
V
Y
N
R
A
I
K
A
A
Site 8
S159
R
A
I
K
A
A
K
S
A
R
D
L
D
M
R
Site 9
S171
D
M
R
D
G
A
C
S
V
P
G
V
T
E
N
Site 10
S182
V
T
E
N
L
G
Q
S
L
W
E
V
S
E
S
Site 11
S189
S
L
W
E
V
S
E
S
H
F
K
Y
P
I
V
Site 12
Y193
V
S
E
S
H
F
K
Y
P
I
V
E
Q
Y
L
Site 13
Y199
K
Y
P
I
V
E
Q
Y
L
K
T
K
K
N
S
Site 14
T202
I
V
E
Q
Y
L
K
T
K
K
N
S
N
N
L
Site 15
S250
E
F
V
C
S
I
K
S
G
I
L
R
N
D
S
Site 16
S257
S
G
I
L
R
N
D
S
T
V
P
D
Q
F
Q
Site 17
T258
G
I
L
R
N
D
S
T
V
P
D
Q
F
Q
C
Site 18
T303
F
V
P
F
R
Q
K
T
D
V
L
K
V
Y
E
Site 19
S322
F
D
V
L
H
F
K
S
E
G
Y
N
D
L
S
Site 20
Y325
L
H
F
K
S
E
G
Y
N
D
L
S
L
Y
N
Site 21
S329
S
E
G
Y
N
D
L
S
L
Y
N
L
F
L
E
Site 22
Y331
G
Y
N
D
L
S
L
Y
N
L
F
L
E
E
N
Site 23
S340
L
F
L
E
E
N
I
S
E
V
K
S
Y
K
C
Site 24
S344
E
N
I
S
E
V
K
S
Y
K
C
L
K
V
L
Site 25
Y345
N
I
S
E
V
K
S
Y
K
C
L
K
V
L
E
Site 26
S356
K
V
L
E
N
I
K
S
S
G
Q
G
I
D
P
Site 27
T382
M
D
V
V
D
G
K
T
P
M
S
A
E
M
R
Site 28
S385
V
D
G
K
T
P
M
S
A
E
M
R
E
E
Q
Site 29
S406
L
Q
G
M
N
I
D
S
E
T
K
A
N
N
G
Site 30
T408
G
M
N
I
D
S
E
T
K
A
N
N
G
E
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation