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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SNX18
Full Name:
Sorting nexin-18
Alias:
SH3 and PX domain-containing protein 3B; SH3PX2; SH3PXD3B; SNAG1; SNXI; Sorting nexin 18; Sorting nexin associated Golgi protein 1; Sorting nexin-associated Golgi protein 1
Type:
Vesicle protein
Mass (Da):
68894
Number AA:
628
UniProt ID:
Q96RF0
International Prot ID:
IPI00045219
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0035091
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
A
L
R
A
R
A
L
Y
D
F
R
S
E
N
P
Site 2
S13
R
A
L
Y
D
F
R
S
E
N
P
G
E
I
S
Site 3
S20
S
E
N
P
G
E
I
S
L
R
E
H
E
V
L
Site 4
S28
L
R
E
H
E
V
L
S
L
C
S
E
Q
D
I
Site 5
S44
G
W
L
E
G
V
N
S
R
G
D
R
G
L
F
Site 6
Y78
G
P
G
A
P
A
R
Y
A
N
V
P
P
G
G
Site 7
S96
L
P
V
A
P
P
A
S
F
K
P
P
P
D
A
Site 8
S117
P
Q
Q
A
P
P
P
S
T
F
Q
P
P
G
A
Site 9
T118
Q
Q
A
P
P
P
S
T
F
Q
P
P
G
A
G
Site 10
Y128
P
P
G
A
G
F
P
Y
G
G
G
A
L
Q
P
Site 11
S136
G
G
G
A
L
Q
P
S
P
Q
Q
L
Y
G
G
Site 12
Y144
P
Q
Q
L
Y
G
G
Y
Q
A
S
Q
G
S
D
Site 13
S147
L
Y
G
G
Y
Q
A
S
Q
G
S
D
D
D
W
Site 14
S150
G
Y
Q
A
S
Q
G
S
D
D
D
W
D
D
E
Site 15
S161
W
D
D
E
W
D
D
S
S
T
V
A
D
E
P
Site 16
S162
D
D
E
W
D
D
S
S
T
V
A
D
E
P
G
Site 17
T163
D
E
W
D
D
S
S
T
V
A
D
E
P
G
A
Site 18
Y176
G
A
L
G
S
G
A
Y
P
D
L
D
G
S
S
Site 19
S182
A
Y
P
D
L
D
G
S
S
S
A
G
V
G
A
Site 20
S184
P
D
L
D
G
S
S
S
A
G
V
G
A
A
G
Site 21
Y193
G
V
G
A
A
G
R
Y
R
L
S
T
R
S
D
Site 22
S196
A
A
G
R
Y
R
L
S
T
R
S
D
L
S
L
Site 23
T197
A
G
R
Y
R
L
S
T
R
S
D
L
S
L
G
Site 24
S199
R
Y
R
L
S
T
R
S
D
L
S
L
G
S
R
Site 25
S202
L
S
T
R
S
D
L
S
L
G
S
R
G
G
S
Site 26
S205
R
S
D
L
S
L
G
S
R
G
G
S
V
P
P
Site 27
S209
S
L
G
S
R
G
G
S
V
P
P
Q
H
H
P
Site 28
S217
V
P
P
Q
H
H
P
S
G
P
K
S
S
A
T
Site 29
S221
H
H
P
S
G
P
K
S
S
A
T
V
S
R
N
Site 30
S222
H
P
S
G
P
K
S
S
A
T
V
S
R
N
L
Site 31
T224
S
G
P
K
S
S
A
T
V
S
R
N
L
N
R
Site 32
S226
P
K
S
S
A
T
V
S
R
N
L
N
R
F
S
Site 33
S233
S
R
N
L
N
R
F
S
T
F
V
K
S
G
G
Site 34
T234
R
N
L
N
R
F
S
T
F
V
K
S
G
G
E
Site 35
Y274
P
E
W
Q
E
N
P
Y
P
F
Q
C
T
I
D
Site 36
T284
Q
C
T
I
D
D
P
T
K
Q
T
K
F
K
G
Site 37
S294
T
K
F
K
G
M
K
S
Y
I
S
Y
K
L
V
Site 38
Y295
K
F
K
G
M
K
S
Y
I
S
Y
K
L
V
P
Site 39
Y298
G
M
K
S
Y
I
S
Y
K
L
V
P
T
H
T
Site 40
T305
Y
K
L
V
P
T
H
T
Q
V
P
V
H
R
R
Site 41
Y320
Y
K
H
F
D
W
L
Y
A
R
L
A
E
K
F
Site 42
S331
A
E
K
F
P
V
I
S
V
P
H
L
P
E
K
Site 43
T341
H
L
P
E
K
Q
A
T
G
R
F
E
E
D
F
Site 44
S350
R
F
E
E
D
F
I
S
K
R
R
K
G
L
I
Site 45
T380
D
V
F
Q
H
F
L
T
C
P
S
S
T
D
E
Site 46
S383
Q
H
F
L
T
C
P
S
S
T
D
E
K
A
W
Site 47
S384
H
F
L
T
C
P
S
S
T
D
E
K
A
W
K
Site 48
S426
L
D
L
Q
E
V
E
S
K
I
D
G
F
K
C
Site 49
S441
F
T
K
K
M
D
D
S
A
L
Q
L
N
H
T
Site 50
T448
S
A
L
Q
L
N
H
T
A
N
E
F
A
R
K
Site 51
Y464
V
T
G
F
K
K
E
Y
Q
K
V
G
Q
S
F
Site 52
S470
E
Y
Q
K
V
G
Q
S
F
R
G
L
S
Q
A
Site 53
S475
G
Q
S
F
R
G
L
S
Q
A
F
E
L
D
Q
Site 54
S570
T
A
V
P
L
W
V
S
E
S
Y
S
T
G
E
Site 55
S572
V
P
L
W
V
S
E
S
Y
S
T
G
E
E
A
Site 56
S574
L
W
V
S
E
S
Y
S
T
G
E
E
A
S
R
Site 57
T598
E
C
K
L
D
C
S
T
G
S
F
L
L
E
Y
Site 58
S613
L
A
L
G
N
E
Y
S
F
S
K
V
Q
R
V
Site 59
S615
L
G
N
E
Y
S
F
S
K
V
Q
R
V
P
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation