PhosphoNET

           
Protein Info 
   
Short Name:  VPS13A
Full Name:  Vacuolar protein sorting-associated protein 13A
Alias:  CHAC; Chorea-acanthocytosis; Chorein; KIAA0986; Vacuolar protein sorting 13 A; Vacuolar protein sorting-associated 13A; VP13A
Type: 
Mass (Da):  360276
Number AA:  3174
UniProt ID:  Q96RL7
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005622     Uniprot OncoNet
Molecular Function:  GO:0005515     PhosphoSite+ KinaseNET
Biological Process:  GO:0006895  GO:0015031   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y18LNRFLGDYVVDLDTS
Site 2S28DLDTSQLSLGIWKGA
Site 3S49QIKENALSQLDVPFK
Site 4Y98VPSSRIKYDPLKEEK
Site 5T138HLPEKQDTFAEKLVT
Site 6S156KNLQVKISSIHIRYE
Site 7T167IRYEDDITNRDKPLS
Site 8S174TNRDKPLSFGISLQN
Site 9S178KPLSFGISLQNLSMQ
Site 10S183GISLQNLSMQTTDQY
Site 11Y215RLDNLFAYWNVKSQM
Site 12Y224NVKSQMFYLSDYDNS
Site 13S226KSQMFYLSDYDNSLD
Site 14Y228QMFYLSDYDNSLDDL
Site 15S231YLSDYDNSLDDLKNG
Site 16Y249ENIVPEGYDFVFRPI
Site 17S268KLVMNRRSDFDFSAP
Site 18S273RRSDFDFSAPKINLE
Site 19Y369VKQYKELYKKKLTSK
Site 20S385PPGELLVSLEELEKT
Site 21T392SLEELEKTLDVFNIT
Site 22T404NITIARQTAEVEVKK
Site 23T453QPDVQPETLEEMLTP
Site 24T459ETLEEMLTPEEKALL
Site 25Y467PEEKALLYEAIGYSE
Site 26T535AQAIKFETKIDSFHI
Site 27S539KFETKIDSFHITGLP
Site 28T543KIDSFHITGLPDNSE
Site 29S549ITGLPDNSEKPRLLS
Site 30S556SEKPRLLSSLDDAMS
Site 31S557EKPRLLSSLDDAMSL
Site 32T577EINPLDETVSQRCII
Site 33S579NPLDETVSQRCIIEA
Site 34Y593AEPLEIIYDARTVNS
Site 35S629TKLEEFRSKTATGLL
Site 36T631LEEFRSKTATGLLYI
Site 37S682LGHLKVTSKSRSELP
Site 38S684HLKVTSKSRSELPDV
Site 39S686KVTSKSRSELPDVKQ
Site 40Y706KEIMDRAYDSFDIQL
Site 41S708IMDRAYDSFDIQLTS
Site 42Y720LTSVQLLYSRVGDNW
Site 43S734WREARKLSVSTQHIL
Site 44S736EARKLSVSTQHILVP
Site 45Y767RMPKFKIYGKLPLIS
Site 46S774YGKLPLISLRISDKK
Site 47S778PLISLRISDKKLQGI
Site 48T799IPKPEPVTEVSAPVK
Site 49S807EVSAPVKSFQIQTST
Site 50S813KSFQIQTSTSLGTSQ
Site 51S815FQIQTSTSLGTSQIS
Site 52S819TSTSLGTSQISQKII
Site 53S833IPLLELPSVSEDDSE
Site 54S835LLELPSVSEDDSEEE
Site 55S839PSVSEDDSEEEFFDA
Site 56S849EFFDAPCSPLEEPLQ
Site 57T859EEPLQFPTGVKSIRT
Site 58S863QFPTGVKSIRTRKLQ
Site 59Y922AEIEIRTYDLKANAF
Site 60Y940FCLKCPEYLDENKKP
Site 61Y949DENKKPVYLVTTLDN
Site 62T963NTMEDLLTLEYVKAE
Site 63Y966EDLLTLEYVKAEKNV
Site 64S978KNVPDLKSTYNNVLQ
Site 65S1017LHNILPQSEEKSAPV
Site 66S1021LPQSEEKSAPVSTTE
Site 67S1025EEKSAPVSTTETEDK
Site 68T1029APVSTTETEDKGDVI
Site 69S1044KKLALKLSTNEDIIT
Site 70S1082IKIEGLDSEMIMRPS
Site 71S1089SEMIMRPSETEINAK
Site 72S1204VKELAQRSSRMALDI
Site 73S1205KELAQRSSRMALDIN
Site 74T1247TNTFHMITESQSSPP
Site 75S1249TFHMITESQSSPPPV
Site 76S1251HMITESQSSPPPVID
Site 77S1252MITESQSSPPPVIDL
Site 78S1265DLITIKLSEMRLYRS
Site 79Y1270KLSEMRLYRSRFIND
Site 80Y1279SRFINDAYQEVLDLL
Site 81S1324KPMEFILSQEDITTI
Site 82T1330LSQEDITTIFKTLHG
Site 83Y1341TLHGNIWYEKDGSAS
Site 84S1346IWYEKDGSASPAVTK
Site 85S1348YEKDGSASPAVTKDQ
Site 86T1352GSASPAVTKDQYSAT
Site 87Y1356PAVTKDQYSATSGVT
Site 88S1357AVTKDQYSATSGVTT
Site 89T1364SATSGVTTNASHHSG
Site 90S1367SGVTTNASHHSGGAT
Site 91T1393RALLVKTTLNISFKT
Site 92S1397VKTTLNISFKTDDLT
Site 93T1404SFKTDDLTMVLYSPG
Site 94Y1408DDLTMVLYSPGPKQA
Site 95S1409DLTMVLYSPGPKQAS
Site 96S1416SPGPKQASFTDVRDP
Site 97T1418GPKQASFTDVRDPSL
Site 98S1424FTDVRDPSLKLAEFK
Site 99S1437FKLENIISTLKMYTD
Site 100S1446LKMYTDGSTFSSFSL
Site 101T1447KMYTDGSTFSSFSLK
Site 102S1450TDGSTFSSFSLKNCI
Site 103T1469RPHVKKATPRMIGLT
Site 104T1476TPRMIGLTVGFDKKD
Site 105Y1489KDMMDIKYRKVRDGC
Site 106T1498KVRDGCVTDAVFQEM
Site 107T1546TAKEEVPTQESVKWE
Site 108T1620VKRKGKITTVLQPCD
Site 109Y1630LQPCDLFYQTTQKGT
Site 110S1645DPQVIDMSVKSLTLK
Site 111S1654KSLTLKVSPVIINTM
Site 112T1670TITSALYTTKETIPE
Site 113S1681TIPEETASSTAHLWE
Site 114S1682IPEETASSTAHLWEK
Site 115S1703KMWFLEESNETEKIA
Site 116T1706FLEESNETEKIAPTT
Site 117S1749VPMLLAKSRFSGEGK
Site 118S1752LLAKSRFSGEGKNWS
Site 119S1759SGEGKNWSSLINLHC
Site 120Y1775LELEVHYYNEMFGVW
Site 121T1794EPLEIDQTEDFRPWN
Site 122S1817AKMAIVESDPEEENY
Site 123Y1824SDPEEENYKVPEYKT
Site 124Y1829ENYKVPEYKTVISFH
Site 125T1831YKVPEYKTVISFHSK
Site 126S1834PEYKTVISFHSKDQL
Site 127T1844SKDQLNITLSKCGLV
Site 128S1906LNIPMAKSYVLKNGE
Site 129Y1907NIPMAKSYVLKNGES
Site 130S1914YVLKNGESLSMDYIR
Site 131S1916LKNGESLSMDYIRTK
Site 132Y1919GESLSMDYIRTKDND
Site 133S1933DHFNAMTSLSSKLFF
Site 134T1957TADKIPLTKVGRRLY
Site 135Y1964TKVGRRLYTVRHRES
Site 136T1965KVGRRLYTVRHRESG
Site 137S1971YTVRHRESGVERSIV
Site 138T1991VEGSKKVTIRSPVQI
Site 139S1994SKKVTIRSPVQIRNH
Site 140S2003VQIRNHFSVPLSVYE
Site 141S2007NHFSVPLSVYEGDTL
Site 142T2017EGDTLLGTASPENEF
Site 143S2019DTLLGTASPENEFNI
Site 144Y2044LKPEDENYQMCEGID
Site 145S2069LLKKKCRSKNPSKES
Site 146S2073KCRSKNPSKESFLIN
Site 147S2076SKNPSKESFLINIVP
Site 148T2089VPEKDNLTSLSVYSE
Site 149S2090PEKDNLTSLSVYSED
Site 150S2092KDNLTSLSVYSEDGW
Site 151Y2094NLTSLSVYSEDGWDL
Site 152Y2124LPYKIAYYIEGIENS
Site 153S2131YIEGIENSVFTLSEG
Site 154S2136ENSVFTLSEGHSAQI
Site 155S2140FTLSEGHSAQICTAQ
Site 156Y2160LHLKLLDYLNHDWKS
Site 157S2179KPNQQDISFVSFTCV
Site 158T2192CVTEMEKTDLDIAVH
Site 159Y2227KTGRMLQYKADGIHR
Site 160Y2240HRKHPPNYKKPVLFS
Site 161T2264NKVQLMVTDSELSNQ
Site 162S2266VQLMVTDSELSNQFS
Site 163S2273SELSNQFSIDTVGSH
Site 164T2276SNQFSIDTVGSHGAV
Site 165Y2292CKGLKMDYQVGVTID
Site 166T2312ITRIVTFTPFYMIKN
Site 167Y2315IVTFTPFYMIKNKSK
Site 168S2321FYMIKNKSKYHISVA
Site 169S2326NKSKYHISVAEEGND
Site 170S2337EGNDKWLSLDLEQCI
Site 171S2353FWPEYASSKLLIQVE
Site 172Y2370EDPPKRIYFNKQENC
Site 173T2403AEHSTVITFLDYHDG
Site 174T2413DYHDGAATFLLINHT
Site 175Y2427TKNELVQYNQSSLSE
Site 176S2431LVQYNQSSLSEIEDS
Site 177S2433QYNQSSLSEIEDSLP
Site 178S2438SLSEIEDSLPPGKAV
Site 179Y2447PPGKAVFYTWADPVG
Site 180T2448PGKAVFYTWADPVGS
Site 181S2465LKWRCRKSHGEVTQK
Site 182S2490EKTIYLVSFFEGLQR
Site 183T2511DPRVFKVTYESEKAE
Site 184S2570KARWKPMSVKHTEKL
Site 185T2574KPMSVKHTEKLEREF
Site 186Y2584LEREFKEYTESSPSE
Site 187T2585EREFKEYTESSPSED
Site 188S2587EFKEYTESSPSEDKV
Site 189S2588FKEYTESSPSEDKVI
Site 190S2590EYTESSPSEDKVIQL
Site 191T2599DKVIQLDTNVPVRLT
Site 192T2606TNVPVRLTPTGHNMK
Site 193Y2626VIALRRNYLPALKVE
Site 194Y2634LPALKVEYNTSAHQS
Site 195S2637LKVEYNTSAHQSSFR
Site 196S2642NTSAHQSSFRIQIYR
Site 197Y2648SSFRIQIYRIQIQNQ
Site 198S2673YPVKPPKSVTMDSAP
Site 199T2675VKPPKSVTMDSAPKP
Site 200S2678PKSVTMDSAPKPFTD
Site 201T2684DSAPKPFTDVSIVMR
Site 202S2687PKPFTDVSIVMRSAG
Site 203S2692DVSIVMRSAGHSQIS
Site 204S2696VMRSAGHSQISRIKY
Site 205Y2703SQISRIKYFKVLIQE
Site 206T2728YALTDLMTEAEVTEN
Site 207T2733LMTEAEVTENTEVEL
Site 208T2754AFKEEYKTASLVDQS
Site 209S2756KEEYKTASLVDQSQV
Site 210S2761TASLVDQSQVSLYEY
Site 211S2764LVDQSQVSLYEYFHI
Site 212Y2766DQSQVSLYEYFHISP
Site 213Y2768SQVSLYEYFHISPIK
Site 214S2779SPIKLHLSVSLSSGR
Site 215S2781IKLHLSVSLSSGREE
Site 216S2783LHLSVSLSSGREEAK
Site 217S2784HLSVSLSSGREEAKD
Site 218S2792GREEAKDSKQNGGLI
Site 219Y2832LAFFELNYQFHTTSD
Site 220S2838NYQFHTTSDLQSEVI
Site 221S2842HTTSDLQSEVIRHYS
Site 222Y2848QSEVIRHYSKQAIKQ
Site 223S2849SEVIRHYSKQAIKQM
Site 224Y2885EGVEAFFYEPYQGAI
Site 225Y2888EAFFYEPYQGAIQGP
Site 226Y2941AMTMDEDYQQKRREA
Site 227T3028FQGIKRATETSEVES
Site 228S3031IKRATETSEVESLRP
Site 229S3035TETSEVESLRPPRFF
Site 230Y3051EDGVIRPYRLRDGTG
Site 231T3057PYRLRDGTGNQMLQV
Site 232Y3073ENGRFAKYKYFTHVM
Site 233Y3075GRFAKYKYFTHVMIN
Site 234T3101VLFVTKGTFGQLTCE
Site 235T3106KGTFGQLTCEWQYSF
Site 236T3117QYSFDEFTKEPFIVH
Site 237S3138EAKERVKSVFHAREF
Site 238T3153GKIINFKTPEDARWI
Site 239S3171LQEAREPSPSL____
Site 240S3173EAREPSPSL______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation