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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GFM1
Full Name:
Elongation factor G, mitochondrial
Alias:
Elongation factor G 1, mitochondrial;Elongation factor G1
Type:
Mass (Da):
83471
Number AA:
751
UniProt ID:
Q96RP9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
G
R
G
R
A
P
A
S
L
G
W
Q
R
K
Q
Site 2
S37
W
K
A
C
R
W
S
S
S
G
V
I
P
N
E
Site 3
S38
K
A
C
R
W
S
S
S
G
V
I
P
N
E
K
Site 4
S52
K
I
R
N
I
G
I
S
A
H
I
D
S
G
K
Site 5
S57
G
I
S
A
H
I
D
S
G
K
T
T
L
T
E
Site 6
T61
H
I
D
S
G
K
T
T
L
T
E
R
V
L
Y
Site 7
T63
D
S
G
K
T
T
L
T
E
R
V
L
Y
Y
T
Site 8
Y68
T
L
T
E
R
V
L
Y
Y
T
G
R
I
A
K
Site 9
Y69
L
T
E
R
V
L
Y
Y
T
G
R
I
A
K
M
Site 10
T70
T
E
R
V
L
Y
Y
T
G
R
I
A
K
M
H
Site 11
S91
G
V
G
A
V
M
D
S
M
E
L
E
R
Q
R
Site 12
T101
L
E
R
Q
R
G
I
T
I
Q
S
A
A
T
Y
Site 13
Y108
T
I
Q
S
A
A
T
Y
T
M
W
K
D
V
N
Site 14
T121
V
N
I
N
I
I
D
T
P
G
H
V
D
F
T
Site 15
T128
T
P
G
H
V
D
F
T
I
E
V
E
R
A
L
Site 16
Y165
V
N
R
Q
M
K
R
Y
N
V
P
F
L
T
F
Site 17
T171
R
Y
N
V
P
F
L
T
F
I
N
K
L
D
R
Site 18
S181
N
K
L
D
R
M
G
S
N
P
A
R
A
L
Q
Site 19
S192
R
A
L
Q
Q
M
R
S
K
L
N
H
N
A
A
Site 20
Y224
L
I
E
E
R
A
I
Y
F
D
G
D
F
G
Q
Site 21
S260
L
I
E
C
V
A
N
S
D
E
Q
L
G
E
M
Site 22
S275
F
L
E
E
K
I
P
S
I
S
D
L
K
L
A
Site 23
S277
E
E
K
I
P
S
I
S
D
L
K
L
A
I
R
Site 24
T287
K
L
A
I
R
R
A
T
L
K
R
S
F
T
P
Site 25
S291
R
R
A
T
L
K
R
S
F
T
P
V
F
L
G
Site 26
Y326
N
P
S
E
V
Q
N
Y
A
I
L
N
K
E
D
Site 27
S335
I
L
N
K
E
D
D
S
K
E
K
T
K
I
L
Site 28
T339
E
D
D
S
K
E
K
T
K
I
L
M
N
S
S
Site 29
S345
K
T
K
I
L
M
N
S
S
R
D
N
S
H
P
Site 30
S346
T
K
I
L
M
N
S
S
R
D
N
S
H
P
F
Site 31
S350
M
N
S
S
R
D
N
S
H
P
F
V
G
L
A
Site 32
T369
V
G
R
F
G
Q
L
T
Y
V
R
S
Y
Q
G
Site 33
Y370
G
R
F
G
Q
L
T
Y
V
R
S
Y
Q
G
E
Site 34
S373
G
Q
L
T
Y
V
R
S
Y
Q
G
E
L
K
K
Site 35
Y374
Q
L
T
Y
V
R
S
Y
Q
G
E
L
K
K
G
Site 36
T383
G
E
L
K
K
G
D
T
I
Y
N
T
R
T
R
Site 37
Y385
L
K
K
G
D
T
I
Y
N
T
R
T
R
K
K
Site 38
T387
K
G
D
T
I
Y
N
T
R
T
R
K
K
V
R
Site 39
S427
L
F
G
I
D
C
A
S
G
D
T
F
T
D
K
Site 40
T430
I
D
C
A
S
G
D
T
F
T
D
K
A
N
S
Site 41
T432
C
A
S
G
D
T
F
T
D
K
A
N
S
G
L
Site 42
S440
D
K
A
N
S
G
L
S
M
E
S
I
H
V
P
Site 43
S452
H
V
P
D
P
V
I
S
I
A
M
K
P
S
N
Site 44
T474
S
K
G
I
G
R
F
T
R
E
D
P
T
F
K
Site 45
T479
R
F
T
R
E
D
P
T
F
K
V
Y
F
D
T
Site 46
Y483
E
D
P
T
F
K
V
Y
F
D
T
E
N
K
E
Site 47
T486
T
F
K
V
Y
F
D
T
E
N
K
E
T
V
I
Site 48
T491
F
D
T
E
N
K
E
T
V
I
S
G
M
G
E
Site 49
S494
E
N
K
E
T
V
I
S
G
M
G
E
L
H
L
Site 50
Y504
G
E
L
H
L
E
I
Y
A
Q
R
L
E
R
E
Site 51
Y512
A
Q
R
L
E
R
E
Y
G
C
P
C
I
T
G
Site 52
T538
A
P
V
P
F
D
F
T
H
K
K
Q
S
G
G
Site 53
Y564
E
P
L
D
P
E
D
Y
T
K
L
E
F
S
D
Site 54
T565
P
L
D
P
E
D
Y
T
K
L
E
F
S
D
E
Site 55
S570
D
Y
T
K
L
E
F
S
D
E
T
F
G
S
N
Site 56
T573
K
L
E
F
S
D
E
T
F
G
S
N
I
P
K
Site 57
S576
F
S
D
E
T
F
G
S
N
I
P
K
Q
F
V
Site 58
S600
A
C
E
K
G
P
L
S
G
H
K
L
S
G
L
Site 59
S625
M
V
D
S
N
E
I
S
F
I
R
A
G
E
G
Site 60
T676
N
R
R
H
G
V
I
T
G
Q
D
G
V
E
D
Site 61
Y684
G
Q
D
G
V
E
D
Y
F
T
L
Y
A
D
V
Site 62
Y688
V
E
D
Y
F
T
L
Y
A
D
V
P
L
N
D
Site 63
T701
N
D
M
F
G
Y
S
T
E
L
R
S
C
T
E
Site 64
S705
G
Y
S
T
E
L
R
S
C
T
E
G
K
G
E
Site 65
T707
S
T
E
L
R
S
C
T
E
G
K
G
E
Y
T
Site 66
T714
T
E
G
K
G
E
Y
T
M
E
Y
S
R
Y
Q
Site 67
Y717
K
G
E
Y
T
M
E
Y
S
R
Y
Q
P
C
L
Site 68
Y720
Y
T
M
E
Y
S
R
Y
Q
P
C
L
P
S
T
Site 69
T727
Y
Q
P
C
L
P
S
T
Q
E
D
V
I
N
K
Site 70
Y735
Q
E
D
V
I
N
K
Y
L
E
A
T
G
Q
L
Site 71
T739
I
N
K
Y
L
E
A
T
G
Q
L
P
V
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation