PhosphoNET

           
Protein Info 
   
Short Name:  ERBB2IP
Full Name:  Protein LAP2
Alias:  Densin-180-like protein; Erbb2 interacting protein; Erbb2-interacting protein; ERBIN; LAP2
Type:  Adapter/scaffold protein
Mass (Da):  158298
Number AA:  1412
UniProt ID:  Q96RT1
International Prot ID:  IPI00438286
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005604  GO:0005737  GO:0030056 Uniprot OncoNet
Molecular Function:  GO:0005176  GO:0005178  GO:0005200 PhosphoSite+ KinaseNET
Biological Process:  GO:0045175  GO:0007155  GO:0007049 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T23CLRGEEETVTTLDYS
Site 2T25RGEEETVTTLDYSHC
Site 3T26GEEETVTTLDYSHCS
Site 4Y29ETVTTLDYSHCSLEQ
Site 5S33TLDYSHCSLEQVPKE
Site 6T43QVPKEIFTFEKTLEE
Site 7T47EIFTFEKTLEELYLD
Site 8Y52EKTLEELYLDANQIE
Site 9S70KQLFNCQSLHKLSLP
Site 10T83LPDNDLTTLPASIAN
Site 11S100NLRELDVSKNGIQEF
Site 12S128EASVNPISKLPDGFS
Site 13S135SKLPDGFSQLLNLTQ
Site 14T179QLKMLPKTMNRLTQL
Site 15T184PKTMNRLTQLERLDL
Site 16S193LERLDLGSNEFTEVP
Site 17T197DLGSNEFTEVPEVLE
Site 18T220WMDANRLTFIPGFIG
Site 19T233IGSLKQLTYLDVSKN
Site 20Y234GSLKQLTYLDVSKNN
Site 21S238QLTYLDVSKNNIEMV
Site 22S250EMVEEGISTCENLQD
Site 23T251MVEEGISTCENLQDL
Site 24S261NLQDLLLSSNSLQQL
Site 25S262LQDLLLSSNSLQQLP
Site 26S264DLLLSSNSLQQLPET
Site 27T271SLQQLPETIGSLKNI
Site 28S274QLPETIGSLKNITTL
Site 29Y290IDENQLMYLPDSIGG
Site 30S307SVEELDCSFNEVEAL
Site 31S316NEVEALPSSIGQLTN
Site 32T322PSSIGQLTNLRTFAA
Site 33T326GQLTNLRTFAADHNY
Site 34Y333TFAADHNYLQQLPPE
Site 35S376KLKVINLSDNRLKNL
Site 36S386RLKNLPFSFTKLQQL
Site 37S399QLTAMWLSDNQSKPL
Site 38S403MWLSDNQSKPLIPLQ
Site 39S415PLQKETDSETQKMVL
Site 40T417QKETDSETQKMVLTN
Site 41Y425QKMVLTNYMFPQQPR
Site 42T433MFPQQPRTEDVMFIS
Site 43S440TEDVMFISDNESFNP
Site 44S444MFISDNESFNPSLWE
Site 45S448DNESFNPSLWEEQRK
Site 46Y483REGNLKRYPTPYPDE
Site 47T485GNLKRYPTPYPDELK
Site 48Y487LKRYPTPYPDELKNM
Site 49T497ELKNMVKTVQTIVHR
Site 50T510HRLKDEETNEDSGRD
Site 51S514DEETNEDSGRDLKPH
Site 52T535NKDVGVKTSESTTTV
Site 53S536KDVGVKTSESTTTVK
Site 54S538VGVKTSESTTTVKSK
Site 55T540VKTSESTTTVKSKVD
Site 56T541KTSESTTTVKSKVDE
Site 57S544ESTTTVKSKVDEREK
Site 58Y552KVDEREKYMIGNSVQ
Site 59S557EKYMIGNSVQKISEP
Site 60S562GNSVQKISEPEAEIS
Site 61S569SEPEAEISPGSLPVT
Site 62S572EAEISPGSLPVTANM
Site 63T576SPGSLPVTANMKASE
Site 64S598HDDVFEESEELSSDE
Site 65S602FEESEELSSDEEMKM
Site 66S603EESEELSSDEEMKMA
Site 67S630QPKVVALSNNKKDDT
Site 68T637SNNKKDDTKETDSLS
Site 69S642DDTKETDSLSDEVTH
Site 70S644TKETDSLSDEVTHNS
Site 71T648DSLSDEVTHNSNQNN
Site 72S656HNSNQNNSNCSSPSR
Site 73S659NQNNSNCSSPSRMSD
Site 74S660QNNSNCSSPSRMSDS
Site 75S662NSNCSSPSRMSDSVS
Site 76S665CSSPSRMSDSVSLNT
Site 77S667SPSRMSDSVSLNTDS
Site 78S669SRMSDSVSLNTDSSQ
Site 79S674SVSLNTDSSQDTSLC
Site 80S675VSLNTDSSQDTSLCS
Site 81T678NTDSSQDTSLCSPVK
Site 82S679TDSSQDTSLCSPVKQ
Site 83S682SQDTSLCSPVKQTHI
Site 84S693QTHIDINSKIRQEDE
Site 85S704QEDENFNSLLQNGDI
Site 86S714QNGDILNSSTEEKFK
Site 87S715NGDILNSSTEEKFKA
Site 88T716GDILNSSTEEKFKAH
Site 89Y733KDFNLPEYDLNVEER
Site 90T751IEKSVDSTATADDTH
Site 91T757STATADDTHKLDHIN
Site 92T775NKLITNDTFQPEIME
Site 93T786EIMERSKTQDIVLGT
Site 94S797VLGTSFLSINSKEET
Site 95S800TSFLSINSKEETEHL
Site 96T804SINSKEETEHLENGN
Site 97Y813HLENGNKYPNLESVN
Site 98S826VNKVNGHSEETSQSP
Site 99S830NGHSEETSQSPNRTE
Site 100S832HSEETSQSPNRTEPH
Site 101T836TSQSPNRTEPHDSDC
Site 102S841NRTEPHDSDCSVDLG
Site 103S844EPHDSDCSVDLGISK
Site 104S850CSVDLGISKSTEDLS
Site 105S852VDLGISKSTEDLSPQ
Site 106T853DLGISKSTEDLSPQK
Site 107S857SKSTEDLSPQKSGPV
Site 108S861EDLSPQKSGPVGSVV
Site 109S866QKSGPVGSVVKSHSI
Site 110S870PVGSVVKSHSITNME
Site 111S872GSVVKSHSITNMEIG
Site 112Y884EIGGLKIYDILSDNG
Site 113S888LKIYDILSDNGPQQP
Site 114T897NGPQQPSTTVKITSA
Site 115S913DGKNIVRSKSATLLY
Site 116S915KNIVRSKSATLLYDQ
Site 117T917 IVRSKSATLLYDQPL
Site 118Y920 SKSATLLYDQPLQVF
Site 119T928DQPLQVFTGSSSSSD
Site 120S930PLQVFTGSSSSSDLI
Site 121S931LQVFTGSSSSSDLIS
Site 122S932QVFTGSSSSSDLISG
Site 123S933VFTGSSSSSDLISGT
Site 124S934FTGSSSSSDLISGTK
Site 125S938SSSSDLISGTKAIFK
Site 126S948KAIFKFDSNHNPEEP
Site 127T962PNIIRGPTSGPQSAP
Site 128S963NIIRGPTSGPQSAPQ
Site 129S967GPTSGPQSAPQIYGP
Site 130Y972PQSAPQIYGPPQYNI
Site 131Y977QIYGPPQYNIQYSSS
Site 132Y981PPQYNIQYSSSAAVK
Site 133S982PQYNIQYSSSAAVKD
Site 134S983QYNIQYSSSAAVKDT
Site 135S984YNIQYSSSAAVKDTL
Site 136T990SSAAVKDTLWHSKQN
Site 137S994VKDTLWHSKQNPQID
Site 138S1004NPQIDHASFPPQLLP
Site 139S1013PPQLLPRSESTENQS
Site 140S1015QLLPRSESTENQSYA
Site 141S1020SESTENQSYAKHSAN
Site 142Y1021ESTENQSYAKHSANM
Site 143Y1042NVRANTAYHLHQRLG
Site 144S1060HGEMWAISPNDRLIP
Site 145S1072LIPAVTRSTIQRQSS
Site 146T1073IPAVTRSTIQRQSSV
Site 147S1078RSTIQRQSSVSSTAS
Site 148S1079STIQRQSSVSSTASV
Site 149S1081IQRQSSVSSTASVNL
Site 150S1082QRQSSVSSTASVNLG
Site 151T1083RQSSVSSTASVNLGD
Site 152S1085SSVSSTASVNLGDPG
Site 153S1093VNLGDPGSTRRAQIP
Site 154T1094NLGDPGSTRRAQIPE
Site 155Y1104 AQIPEGDYLSYREFH
Site 156S1106IPEGDYLSYREFHSA
Site 157Y1107PEGDYLSYREFHSAG
Site 158T1116EFHSAGRTPPMMPGS
Site 159S1123TPPMMPGSQRPLSAR
Site 160S1128PGSQRPLSARTYSID
Site 161Y1132RPLSARTYSIDGPNA
Site 162S1133PLSARTYSIDGPNAS
Site 163S1140SIDGPNASRPQSARP
Site 164S1144PNASRPQSARPSINE
Site 165S1148RPQSARPSINEIPER
Site 166T1156INEIPERTMSVSDFN
Site 167S1158EIPERTMSVSDFNYS
Site 168S1160PERTMSVSDFNYSRT
Site 169Y1164MSVSDFNYSRTSPSK
Site 170S1165SVSDFNYSRTSPSKR
Site 171T1167SDFNYSRTSPSKRPN
Site 172S1168DFNYSRTSPSKRPNA
Site 173S1170NYSRTSPSKRPNARV
Site 174S1179RPNARVGSEHSLLDP
Site 175S1182ARVGSEHSLLDPPGK
Site 176S1190LLDPPGKSKVPRDWR
Site 177T1216LEKKHPQTSSSGDPC
Site 178S1217EKKHPQTSSSGDPCQ
Site 179S1218KKHPQTSSSGDPCQD
Site 180S1219KHPQTSSSGDPCQDG
Site 181Y1235FISGQQNYSSATLSH
Site 182S1236ISGQQNYSSATLSHK
Site 183S1237SGQQNYSSATLSHKD
Site 184S1241NYSSATLSHKDVPPD
Site 185S1249HKDVPPDSLMKMPLS
Site 186S1256SLMKMPLSNGQMGQP
Site 187Y1270PLRPQANYSQIHHPP
Site 188S1271LRPQANYSQIHHPPQ
Site 189S1280IHHPPQASVARHPSR
Site 190S1286ASVARHPSREQLIDY
Site 191Y1293SREQLIDYLMLKVAH
Site 192Y1304KVAHQPPYTQPHCSP
Site 193T1305VAHQPPYTQPHCSPR
Site 194S1310PYTQPHCSPRQGHEL
Site 195S1335KDPELGFSISGGVGG
Site 196S1337PELGFSISGGVGGRG
Site 197S1366VQPEGPASKLLQPGD
Site 198Y1381KIIQANGYSFINIEH
Site 199S1382IIQANGYSFINIEHG
Site 200S1393IEHGQAVSLLKTFQN
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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