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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIB1
Full Name:
Tribbles homolog 1
Alias:
G-protein-coupled receptor-induced gene 2 protein;SKIP1
Type:
Mass (Da):
41009
Number AA:
372
UniProt ID:
Q96RU8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
R
V
G
P
V
R
S
A
M
S
G
A
S
Q
Site 2
S11
G
P
V
R
S
A
M
S
G
A
S
Q
P
R
G
Site 3
S14
R
S
A
M
S
G
A
S
Q
P
R
G
P
A
L
Site 4
T26
P
A
L
L
F
P
A
T
R
G
V
P
A
K
R
Site 5
S51
A
A
K
C
P
R
L
S
E
C
S
S
P
P
D
Site 6
S54
C
P
R
L
S
E
C
S
S
P
P
D
Y
L
S
Site 7
S55
P
R
L
S
E
C
S
S
P
P
D
Y
L
S
P
Site 8
Y59
E
C
S
S
P
P
D
Y
L
S
P
P
G
S
P
Site 9
S61
S
S
P
P
D
Y
L
S
P
P
G
S
P
C
S
Site 10
S65
D
Y
L
S
P
P
G
S
P
C
S
P
Q
P
P
Site 11
S68
S
P
P
G
S
P
C
S
P
Q
P
P
P
A
A
Site 12
S82
A
P
G
A
G
G
G
S
G
S
A
P
G
P
S
Site 13
S84
G
A
G
G
G
S
G
S
A
P
G
P
S
R
I
Site 14
T113
S
R
A
L
C
I
H
T
G
R
E
L
R
C
K
Site 15
Y127
K
V
F
P
I
K
H
Y
Q
D
K
I
R
P
Y
Site 16
Y134
Y
Q
D
K
I
R
P
Y
I
Q
L
P
S
H
S
Site 17
S139
R
P
Y
I
Q
L
P
S
H
S
N
I
T
G
I
Site 18
S169
K
D
F
G
D
M
H
S
Y
V
R
S
R
K
R
Site 19
Y170
D
F
G
D
M
H
S
Y
V
R
S
R
K
R
L
Site 20
S173
D
M
H
S
Y
V
R
S
R
K
R
L
R
E
E
Site 21
S214
K
L
R
K
F
V
F
S
T
E
E
R
T
Q
L
Site 22
T215
L
R
K
F
V
F
S
T
E
E
R
T
Q
L
R
Site 23
S225
R
T
Q
L
R
L
E
S
L
E
D
T
H
I
M
Site 24
T229
R
L
E
S
L
E
D
T
H
I
M
K
G
E
D
Site 25
S240
K
G
E
D
D
A
L
S
D
K
H
G
C
P
A
Site 26
Y248
D
K
H
G
C
P
A
Y
V
S
P
E
I
L
N
Site 27
S250
H
G
C
P
A
Y
V
S
P
E
I
L
N
T
T
Site 28
T256
V
S
P
E
I
L
N
T
T
G
T
Y
S
G
K
Site 29
T257
S
P
E
I
L
N
T
T
G
T
Y
S
G
K
A
Site 30
T259
E
I
L
N
T
T
G
T
Y
S
G
K
A
A
D
Site 31
Y282
Y
T
L
L
V
G
R
Y
P
F
H
D
S
D
P
Site 32
S287
G
R
Y
P
F
H
D
S
D
P
S
A
L
F
S
Site 33
S290
P
F
H
D
S
D
P
S
A
L
F
S
K
I
R
Site 34
S294
S
D
P
S
A
L
F
S
K
I
R
R
G
Q
F
Site 35
S317
K
A
R
C
L
I
R
S
L
L
R
R
E
P
S
Site 36
S324
S
L
L
R
R
E
P
S
E
R
L
T
A
P
E
Site 37
T328
R
E
P
S
E
R
L
T
A
P
E
I
L
L
H
Site 38
Y346
E
S
V
L
E
P
G
Y
I
D
S
E
I
G
T
Site 39
S349
L
E
P
G
Y
I
D
S
E
I
G
T
S
D
Q
Site 40
S354
I
D
S
E
I
G
T
S
D
Q
I
V
P
E
Y
Site 41
Y361
S
D
Q
I
V
P
E
Y
Q
E
D
S
D
I
S
Site 42
S365
V
P
E
Y
Q
E
D
S
D
I
S
S
F
F
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation