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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CRAMP1L
Full Name:
Protein cramped-like
Alias:
Crm, cramped-like; CRML; Hematological and neurological expressed 1-like protein; KIAA1426; TCE4; T-complex expressed gene 4
Type:
Unknown function
Mass (Da):
135182
Number AA:
1266
UniProt ID:
Q96RY5
International Prot ID:
IPI00477543
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
V
K
L
G
D
G
G
S
G
E
D
G
L
K
K
Site 2
S27
K
R
A
A
D
E
E
S
L
E
G
E
G
A
G
Site 3
T45
A
A
E
E
S
S
G
T
K
R
D
E
K
T
P
Site 4
T51
G
T
K
R
D
E
K
T
P
R
A
G
A
D
G
Site 5
S70
P
G
A
P
Q
A
P
S
P
P
Q
G
S
P
Q
Site 6
S75
A
P
S
P
P
Q
G
S
P
Q
D
Q
H
H
F
Site 7
S86
Q
H
H
F
L
R
S
S
V
R
P
Q
S
K
R
Site 8
S91
R
S
S
V
R
P
Q
S
K
R
P
R
K
D
P
Site 9
S100
R
P
R
K
D
P
P
S
A
V
G
S
G
N
A
Site 10
S104
D
P
P
S
A
V
G
S
G
N
A
G
G
S
G
Site 11
S110
G
S
G
N
A
G
G
S
G
P
R
G
K
D
R
Site 12
S136
S
R
V
P
F
G
G
S
R
S
S
S
R
N
L
Site 13
S138
V
P
F
G
G
S
R
S
S
S
R
N
L
G
S
Site 14
S139
P
F
G
G
S
R
S
S
S
R
N
L
G
S
S
Site 15
S140
F
G
G
S
R
S
S
S
R
N
L
G
S
S
G
Site 16
S146
S
S
R
N
L
G
S
S
G
G
E
K
E
E
G
Site 17
S162
K
V
R
R
Q
W
E
S
W
S
T
E
D
K
N
Site 18
T170
W
S
T
E
D
K
N
T
F
F
E
G
L
Y
E
Site 19
Y176
N
T
F
F
E
G
L
Y
E
H
G
K
D
F
E
Site 20
S201
K
K
K
G
K
P
A
S
M
V
K
N
K
E
Q
Site 21
S237
F
S
R
G
L
K
K
S
S
Q
E
L
Y
G
L
Site 22
S238
S
R
G
L
K
K
S
S
Q
E
L
Y
G
L
I
Site 23
Y242
K
K
S
S
Q
E
L
Y
G
L
I
C
Y
G
E
Site 24
T276
L
I
Q
V
G
A
T
T
V
R
Y
K
G
R
N
Site 25
Y279
V
G
A
T
T
V
R
Y
K
G
R
N
L
R
I
Site 26
S304
L
C
D
P
D
G
L
S
D
E
E
D
Q
K
P
Site 27
S335
H
A
W
A
R
V
Q
S
L
A
Q
N
P
R
L
Site 28
S354
E
L
H
R
K
V
S
S
L
I
E
F
L
K
Q
Site 29
T373
H
E
V
R
V
R
K
T
L
E
E
R
Q
L
Q
Site 30
S382
E
E
R
Q
L
Q
D
S
C
S
A
P
M
Q
E
Site 31
S384
R
Q
L
Q
D
S
C
S
A
P
M
Q
E
K
V
Site 32
T404
P
G
E
N
C
T
L
T
P
L
P
G
V
A
R
Site 33
T453
G
I
Q
S
G
Q
G
T
A
R
G
Q
V
K
C
Site 34
S463
G
Q
V
K
C
P
R
S
G
A
E
G
K
G
V
Site 35
S482
P
A
A
D
A
L
Q
S
S
G
E
S
S
P
E
Site 36
S483
A
A
D
A
L
Q
S
S
G
E
S
S
P
E
S
Site 37
S486
A
L
Q
S
S
G
E
S
S
P
E
S
A
P
G
Site 38
S487
L
Q
S
S
G
E
S
S
P
E
S
A
P
G
E
Site 39
S490
S
G
E
S
S
P
E
S
A
P
G
E
G
A
A
Site 40
S499
P
G
E
G
A
A
L
S
L
S
S
P
D
A
P
Site 41
S501
E
G
A
A
L
S
L
S
S
P
D
A
P
D
R
Site 42
S502
G
A
A
L
S
L
S
S
P
D
A
P
D
R
P
Site 43
T516
P
P
P
R
H
Q
D
T
G
P
C
L
E
K
T
Site 44
T523
T
G
P
C
L
E
K
T
P
A
E
G
R
D
S
Site 45
S530
T
P
A
E
G
R
D
S
P
T
R
E
P
G
A
Site 46
T532
A
E
G
R
D
S
P
T
R
E
P
G
A
L
P
Site 47
S553
P
D
L
E
D
E
L
S
L
L
D
P
L
P
R
Site 48
Y561
L
L
D
P
L
P
R
Y
L
K
S
C
Q
D
L
Site 49
S564
P
L
P
R
Y
L
K
S
C
Q
D
L
I
V
P
Site 50
T579
E
Q
C
R
C
A
D
T
R
P
G
S
E
Q
P
Site 51
S583
C
A
D
T
R
P
G
S
E
Q
P
P
L
G
G
Site 52
S613
D
L
A
P
T
G
P
S
P
R
P
G
P
G
L
Site 53
S642
E
E
L
Q
E
K
G
S
P
A
G
P
P
P
S
Site 54
S649
S
P
A
G
P
P
P
S
Q
G
Q
P
A
A
R
Site 55
S664
P
P
K
E
V
P
A
S
R
L
A
Q
Q
L
R
Site 56
S682
W
N
L
Q
T
S
E
S
L
T
L
A
E
V
Y
Site 57
Y702
P
S
K
L
Q
L
E
Y
D
W
L
G
P
G
R
Site 58
S716
R
Q
D
P
R
P
G
S
L
P
T
A
L
H
K
Site 59
T719
P
R
P
G
S
L
P
T
A
L
H
K
Q
R
L
Site 60
S753
A
N
T
I
S
T
A
S
V
R
P
A
Q
E
E
Site 61
T764
A
Q
E
E
Q
S
M
T
P
P
G
K
V
V
T
Site 62
T771
T
P
P
G
K
V
V
T
V
S
S
R
S
P
R
Site 63
S773
P
G
K
V
V
T
V
S
S
R
S
P
R
C
P
Site 64
S774
G
K
V
V
T
V
S
S
R
S
P
R
C
P
R
Site 65
S776
V
V
T
V
S
S
R
S
P
R
C
P
R
N
Q
Site 66
S785
R
C
P
R
N
Q
A
S
L
R
S
S
K
T
F
Site 67
S788
R
N
Q
A
S
L
R
S
S
K
T
F
P
P
S
Site 68
S789
N
Q
A
S
L
R
S
S
K
T
F
P
P
S
S
Site 69
T791
A
S
L
R
S
S
K
T
F
P
P
S
S
A
P
Site 70
S795
S
S
K
T
F
P
P
S
S
A
P
C
S
S
G
Site 71
S796
S
K
T
F
P
P
S
S
A
P
C
S
S
G
L
Site 72
S800
P
P
S
S
A
P
C
S
S
G
L
R
N
P
P
Site 73
S801
P
S
S
A
P
C
S
S
G
L
R
N
P
P
R
Site 74
S816
P
L
L
V
P
G
P
S
S
T
G
S
N
D
S
Site 75
S817
L
L
V
P
G
P
S
S
T
G
S
N
D
S
D
Site 76
S820
P
G
P
S
S
T
G
S
N
D
S
D
G
G
L
Site 77
S823
S
S
T
G
S
N
D
S
D
G
G
L
F
A
V
Site 78
T832
G
G
L
F
A
V
P
T
T
L
P
P
N
S
R
Site 79
T833
G
L
F
A
V
P
T
T
L
P
P
N
S
R
H
Site 80
S838
P
T
T
L
P
P
N
S
R
H
G
K
L
F
S
Site 81
S845
S
R
H
G
K
L
F
S
P
S
K
E
A
E
L
Site 82
S847
H
G
K
L
F
S
P
S
K
E
A
E
L
T
F
Site 83
T853
P
S
K
E
A
E
L
T
F
R
Q
H
L
N
S
Site 84
S860
T
F
R
Q
H
L
N
S
I
S
M
Q
S
D
F
Site 85
S862
R
Q
H
L
N
S
I
S
M
Q
S
D
F
F
L
Site 86
S865
L
N
S
I
S
M
Q
S
D
F
F
L
P
K
P
Site 87
T889
K
P
L
V
V
Q
R
T
L
L
P
R
P
S
E
Site 88
S895
R
T
L
L
P
R
P
S
E
N
Q
S
H
N
V
Site 89
S899
P
R
P
S
E
N
Q
S
H
N
V
C
S
F
S
Site 90
S904
N
Q
S
H
N
V
C
S
F
S
I
L
S
N
S
Site 91
S911
S
F
S
I
L
S
N
S
S
V
T
G
R
G
S
Site 92
T914
I
L
S
N
S
S
V
T
G
R
G
S
F
R
P
Site 93
S918
S
S
V
T
G
R
G
S
F
R
P
I
Q
S
S
Site 94
S925
S
F
R
P
I
Q
S
S
L
T
K
A
A
L
S
Site 95
T927
R
P
I
Q
S
S
L
T
K
A
A
L
S
R
P
Site 96
T972
N
P
L
P
A
L
D
T
E
G
L
S
G
I
S
Site 97
S979
T
E
G
L
S
G
I
S
P
L
S
S
D
E
V
Site 98
T987
P
L
S
S
D
E
V
T
G
A
I
S
G
Q
D
Site 99
S991
D
E
V
T
G
A
I
S
G
Q
D
S
T
G
T
Site 100
S995
G
A
I
S
G
Q
D
S
T
G
T
H
Q
D
G
Site 101
T996
A
I
S
G
Q
D
S
T
G
T
H
Q
D
G
D
Site 102
T1004
G
T
H
Q
D
G
D
T
L
P
T
V
G
G
S
Site 103
T1007
Q
D
G
D
T
L
P
T
V
G
G
S
D
P
F
Site 104
S1016
G
G
S
D
P
F
V
S
I
P
S
R
P
E
Q
Site 105
S1029
E
Q
E
P
V
A
D
S
F
Q
G
S
S
V
L
Site 106
S1051
A
P
L
Q
N
G
L
S
I
P
L
S
S
S
E
Site 107
S1055
N
G
L
S
I
P
L
S
S
S
E
S
S
S
T
Site 108
S1056
G
L
S
I
P
L
S
S
S
E
S
S
S
T
R
Site 109
S1057
L
S
I
P
L
S
S
S
E
S
S
S
T
R
L
Site 110
S1059
I
P
L
S
S
S
E
S
S
S
T
R
L
S
P
Site 111
S1060
P
L
S
S
S
E
S
S
S
T
R
L
S
P
P
Site 112
S1061
L
S
S
S
E
S
S
S
T
R
L
S
P
P
D
Site 113
T1062
S
S
S
E
S
S
S
T
R
L
S
P
P
D
V
Site 114
S1065
G
P
A
V
S
D
L
S
Q
_
_
_
_
_
_
Site 115
S1086
G
P
P
E
D
A
L
S
Q
G
E
P
A
T
H
Site 116
T1092
L
S
Q
G
E
P
A
T
H
I
S
D
S
I
I
Site 117
S1115
Y
G
E
G
V
P
L
S
P
A
K
L
N
G
S
Site 118
S1122
S
P
A
K
L
N
G
S
D
S
S
K
S
L
P
Site 119
S1124
A
K
L
N
G
S
D
S
S
K
S
L
P
S
P
Site 120
S1125
K
L
N
G
S
D
S
S
K
S
L
P
S
P
S
Site 121
S1127
N
G
S
D
S
S
K
S
L
P
S
P
S
S
S
Site 122
S1130
D
S
S
K
S
L
P
S
P
S
S
S
P
Q
P
Site 123
S1132
S
K
S
L
P
S
P
S
S
S
P
Q
P
H
W
Site 124
S1133
K
S
L
P
S
P
S
S
S
P
Q
P
H
W
I
Site 125
S1134
S
L
P
S
P
S
S
S
P
Q
P
H
W
I
A
Site 126
Y1150
P
T
H
D
P
Q
W
Y
P
S
D
S
T
D
S
Site 127
S1152
H
D
P
Q
W
Y
P
S
D
S
T
D
S
S
L
Site 128
S1154
P
Q
W
Y
P
S
D
S
T
D
S
S
L
S
S
Site 129
T1155
Q
W
Y
P
S
D
S
T
D
S
S
L
S
S
L
Site 130
S1157
Y
P
S
D
S
T
D
S
S
L
S
S
L
F
A
Site 131
S1158
P
S
D
S
T
D
S
S
L
S
S
L
F
A
S
Site 132
S1168
S
L
F
A
S
F
I
S
P
E
K
S
R
K
M
Site 133
S1172
S
F
I
S
P
E
K
S
R
K
M
L
P
T
P
Site 134
T1178
K
S
R
K
M
L
P
T
P
I
G
T
N
S
G
Site 135
S1184
P
T
P
I
G
T
N
S
G
T
S
L
L
G
P
Site 136
S1192
G
T
S
L
L
G
P
S
L
L
D
G
N
S
R
Site 137
S1198
P
S
L
L
D
G
N
S
R
D
S
F
V
S
R
Site 138
S1201
L
D
G
N
S
R
D
S
F
V
S
R
S
L
A
Site 139
S1204
N
S
R
D
S
F
V
S
R
S
L
A
D
V
A
Site 140
S1206
R
D
S
F
V
S
R
S
L
A
D
V
A
E
V
Site 141
Y1229
M
N
E
N
S
I
D
Y
I
S
R
F
N
D
L
Site 142
S1241
N
D
L
A
Q
E
L
S
I
A
E
P
G
R
R
Site 143
S1262
G
G
G
G
P
A
V
S
D
L
S
Q
_
_
_
Site 144
S1265
G
P
A
V
S
D
L
S
Q
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation