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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PIGS
Full Name:
GPI transamidase component PIG-S
Alias:
Phosphatidylinositol-glycan biosynthesis class S protein
Type:
Mass (Da):
61656
Number AA:
555
UniProt ID:
Q96S52
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T41
L
W
W
K
T
T
E
T
Y
R
A
S
L
P
Y
Site 2
S45
T
T
E
T
Y
R
A
S
L
P
Y
S
Q
I
S
Site 3
Y48
T
Y
R
A
S
L
P
Y
S
Q
I
S
G
L
N
Site 4
S49
Y
R
A
S
L
P
Y
S
Q
I
S
G
L
N
A
Site 5
S73
T
V
V
F
T
R
E
S
V
P
L
D
D
Q
E
Site 6
T85
D
Q
E
K
L
P
F
T
V
V
H
E
R
E
I
Site 7
Y96
E
R
E
I
P
L
K
Y
K
M
K
I
K
C
R
Site 8
Y108
K
C
R
F
Q
K
A
Y
R
R
A
L
D
H
E
Site 9
S120
D
H
E
E
E
A
L
S
S
G
S
V
Q
E
A
Site 10
S121
H
E
E
E
A
L
S
S
G
S
V
Q
E
A
E
Site 11
S123
E
E
A
L
S
S
G
S
V
Q
E
A
E
A
M
Site 12
S141
P
Q
E
Q
A
E
G
S
L
T
V
Y
V
I
S
Site 13
T143
E
Q
A
E
G
S
L
T
V
Y
V
I
S
E
H
Site 14
Y145
A
E
G
S
L
T
V
Y
V
I
S
E
H
S
S
Site 15
S152
Y
V
I
S
E
H
S
S
L
L
P
Q
D
M
M
Site 16
S160
L
L
P
Q
D
M
M
S
Y
I
G
P
K
R
T
Site 17
Y161
L
P
Q
D
M
M
S
Y
I
G
P
K
R
T
A
Site 18
S214
H
L
P
E
D
K
W
S
A
E
K
R
R
P
L
Site 19
S223
E
K
R
R
P
L
K
S
S
L
G
Y
E
I
T
Site 20
S224
K
R
R
P
L
K
S
S
L
G
Y
E
I
T
F
Site 21
T230
S
S
L
G
Y
E
I
T
F
S
L
L
N
P
D
Site 22
S232
L
G
Y
E
I
T
F
S
L
L
N
P
D
P
K
Site 23
Y244
D
P
K
S
H
D
V
Y
W
D
I
E
G
A
V
Site 24
Y254
I
E
G
A
V
R
R
Y
V
Q
P
F
L
N
A
Site 25
S288
G
V
N
P
R
F
D
S
A
S
S
S
Y
Y
L
Site 26
S290
N
P
R
F
D
S
A
S
S
S
Y
Y
L
D
M
Site 27
S292
R
F
D
S
A
S
S
S
Y
Y
L
D
M
H
S
Site 28
Y294
D
S
A
S
S
S
Y
Y
L
D
M
H
S
L
P
Site 29
S309
H
V
I
N
P
V
E
S
R
L
G
S
S
A
A
Site 30
S313
P
V
E
S
R
L
G
S
S
A
A
S
L
Y
P
Site 31
S334
Y
V
P
E
L
A
H
S
P
L
Y
I
Q
D
K
Site 32
Y337
E
L
A
H
S
P
L
Y
I
Q
D
K
D
G
A
Site 33
Y362
R
W
G
G
I
M
V
Y
N
V
D
S
K
T
Y
Site 34
T368
V
Y
N
V
D
S
K
T
Y
N
A
S
V
L
P
Site 35
T420
P
T
S
E
G
L
M
T
W
E
L
D
R
L
L
Site 36
S431
D
R
L
L
W
A
R
S
V
E
N
L
A
T
A
Site 37
T437
R
S
V
E
N
L
A
T
A
T
T
T
L
T
S
Site 38
S481
K
S
A
E
E
L
A
S
G
H
L
A
S
A
F
Site 39
Y512
P
S
L
L
H
L
L
Y
F
P
D
D
Q
K
F
Site 40
S547
I
F
L
E
T
R
K
S
W
R
K
P
E
K
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation