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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WRNIP1
Full Name:
ATPase WRNIP1
Alias:
bA420G6.2; FLJ22526; Werner helicase interacting protein; Werner helicase interacting protein 1; WHIP; WRIP1
Type:
DNA binding protein, helicase
Mass (Da):
72133
Number AA:
665
UniProt ID:
Q96S55
International Prot ID:
IPI00290314
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0048471
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0000731
GO:0030174
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
P
E
D
D
P
F
L
S
Q
L
H
Q
V
Q
C
Site 2
S65
G
E
R
A
K
G
P
S
P
P
G
A
K
R
R
Site 3
S75
G
A
K
R
R
R
L
S
E
S
S
A
L
K
Q
Site 4
S77
K
R
R
R
L
S
E
S
S
A
L
K
Q
P
A
Site 5
S78
R
R
R
L
S
E
S
S
A
L
K
Q
P
A
T
Site 6
T85
S
A
L
K
Q
P
A
T
P
T
A
A
E
S
S
Site 7
T87
L
K
Q
P
A
T
P
T
A
A
E
S
S
E
G
Site 8
S91
A
T
P
T
A
A
E
S
S
E
G
E
G
E
E
Site 9
S92
T
P
T
A
A
E
S
S
E
G
E
G
E
E
G
Site 10
T105
E
G
D
D
G
G
E
T
E
S
R
E
S
Y
D
Site 11
S110
G
E
T
E
S
R
E
S
Y
D
A
P
P
T
P
Site 12
Y111
E
T
E
S
R
E
S
Y
D
A
P
P
T
P
S
Site 13
T116
E
S
Y
D
A
P
P
T
P
S
G
A
R
L
I
Site 14
S118
Y
D
A
P
P
T
P
S
G
A
R
L
I
P
D
Site 15
S131
P
D
F
P
V
A
R
S
S
S
P
G
R
K
G
Site 16
S132
D
F
P
V
A
R
S
S
S
P
G
R
K
G
S
Site 17
S133
F
P
V
A
R
S
S
S
P
G
R
K
G
S
G
Site 18
S139
S
S
P
G
R
K
G
S
G
K
R
P
A
A
A
Site 19
S151
A
A
A
A
A
A
G
S
A
S
P
R
S
W
D
Site 20
S153
A
A
A
A
G
S
A
S
P
R
S
W
D
E
A
Site 21
S156
A
G
S
A
S
P
R
S
W
D
E
A
E
A
Q
Site 22
T230
Q
G
K
P
L
A
D
T
M
R
P
D
T
L
Q
Site 23
T235
A
D
T
M
R
P
D
T
L
Q
D
Y
F
G
Q
Site 24
Y239
R
P
D
T
L
Q
D
Y
F
G
Q
S
K
A
V
Site 25
T250
S
K
A
V
G
Q
D
T
L
L
R
S
L
L
E
Site 26
S254
G
Q
D
T
L
L
R
S
L
L
E
T
N
E
I
Site 27
S283
T
L
A
H
I
I
A
S
N
S
K
K
H
S
I
Site 28
S285
A
H
I
I
A
S
N
S
K
K
H
S
I
R
F
Site 29
S289
A
S
N
S
K
K
H
S
I
R
F
V
T
L
S
Site 30
T294
K
H
S
I
R
F
V
T
L
S
A
T
N
A
K
Site 31
S296
S
I
R
F
V
T
L
S
A
T
N
A
K
T
N
Site 32
S317
K
Q
A
Q
N
E
K
S
F
F
K
R
K
T
I
Site 33
T323
K
S
F
F
K
R
K
T
I
L
F
I
D
E
I
Site 34
S336
E
I
H
R
F
N
K
S
Q
Q
D
T
F
L
P
Site 35
T340
F
N
K
S
Q
Q
D
T
F
L
P
H
V
E
C
Site 36
S361
G
A
T
T
E
N
P
S
F
Q
V
N
A
A
L
Site 37
T387
L
P
V
E
A
M
V
T
I
L
M
R
A
I
N
Site 38
S403
L
G
I
H
V
L
D
S
S
R
P
T
D
P
L
Site 39
S404
G
I
H
V
L
D
S
S
R
P
T
D
P
L
S
Site 40
T407
V
L
D
S
S
R
P
T
D
P
L
S
H
S
S
Site 41
S411
S
R
P
T
D
P
L
S
H
S
S
N
S
S
S
Site 42
S413
P
T
D
P
L
S
H
S
S
N
S
S
S
E
P
Site 43
S414
T
D
P
L
S
H
S
S
N
S
S
S
E
P
A
Site 44
S416
P
L
S
H
S
S
N
S
S
S
E
P
A
M
F
Site 45
S417
L
S
H
S
S
N
S
S
S
E
P
A
M
F
I
Site 46
S418
S
H
S
S
N
S
S
S
E
P
A
M
F
I
E
Site 47
T431
I
E
D
K
A
V
D
T
L
A
Y
L
S
D
G
Site 48
Y434
K
A
V
D
T
L
A
Y
L
S
D
G
D
A
R
Site 49
S457
A
V
L
A
R
L
S
S
R
K
M
F
C
K
K
Site 50
S465
R
K
M
F
C
K
K
S
G
Q
S
Y
S
P
S
Site 51
S468
F
C
K
K
S
G
Q
S
Y
S
P
S
R
V
L
Site 52
S470
K
K
S
G
Q
S
Y
S
P
S
R
V
L
I
T
Site 53
S472
S
G
Q
S
Y
S
P
S
R
V
L
I
T
E
N
Site 54
Y492
L
Q
R
S
H
I
L
Y
D
R
A
G
E
E
H
Site 55
Y500
D
R
A
G
E
E
H
Y
N
C
I
S
A
L
H
Site 56
S509
C
I
S
A
L
H
K
S
M
R
G
S
D
Q
N
Site 57
S513
L
H
K
S
M
R
G
S
D
Q
N
A
S
L
Y
Site 58
S518
R
G
S
D
Q
N
A
S
L
Y
W
L
A
R
M
Site 59
Y520
S
D
Q
N
A
S
L
Y
W
L
A
R
M
L
E
Site 60
Y534
E
G
G
E
D
P
L
Y
V
A
R
R
L
V
R
Site 61
S544
R
R
L
V
R
F
A
S
E
D
I
G
L
A
D
Site 62
Y562
L
T
Q
A
V
A
A
Y
Q
G
C
H
F
I
G
Site 63
S590
Y
F
A
R
A
P
K
S
I
E
V
Y
S
A
Y
Site 64
Y594
A
P
K
S
I
E
V
Y
S
A
Y
N
N
V
K
Site 65
Y631
R
L
M
K
D
L
G
Y
G
K
G
Y
K
Y
N
Site 66
Y635
D
L
G
Y
G
K
G
Y
K
Y
N
P
M
Y
S
Site 67
Y637
G
Y
G
K
G
Y
K
Y
N
P
M
Y
S
E
P
Site 68
Y641
G
Y
K
Y
N
P
M
Y
S
E
P
V
D
Q
E
Site 69
Y649
S
E
P
V
D
Q
E
Y
L
P
E
E
L
R
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation