KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DCLRE1C
Full Name:
Protein artemis
Alias:
DNA cross-link repair 1C protein;Protein A-SCID;SNM1 homolog C;SNM1-like protein
Type:
DNA repair protein
Mass (Da):
78436
Number AA:
692
UniProt ID:
Q96SD1
International Prot ID:
IPI00290459
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008409
GO:0000287
GO:0000014
PhosphoSite+
KinaseNET
Biological Process:
GO:0006310
GO:0006955
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
F
E
G
Q
M
A
E
Y
P
T
I
S
I
D
R
Site 2
S15
M
A
E
Y
P
T
I
S
I
D
R
F
D
R
E
Site 3
Y29
E
N
L
R
A
R
A
Y
F
L
S
H
C
H
K
Site 4
T46
M
K
G
L
R
A
P
T
L
K
R
R
L
E
C
Site 5
S54
L
K
R
R
L
E
C
S
L
K
V
Y
L
Y
C
Site 6
T71
V
T
K
E
L
L
L
T
S
P
K
Y
R
F
W
Site 7
S72
T
K
E
L
L
L
T
S
P
K
Y
R
F
W
K
Site 8
Y75
L
L
L
T
S
P
K
Y
R
F
W
K
K
R
I
Site 9
S84
F
W
K
K
R
I
I
S
I
E
I
E
T
P
T
Site 10
S94
I
E
T
P
T
Q
I
S
L
V
D
E
A
S
G
Site 11
S100
I
S
L
V
D
E
A
S
G
E
K
E
E
I
V
Site 12
T130
L
F
Q
G
N
N
G
T
V
L
Y
T
G
D
F
Site 13
Y133
G
N
N
G
T
V
L
Y
T
G
D
F
R
L
A
Site 14
S152
A
R
M
E
L
L
H
S
G
G
R
V
K
D
I
Site 15
S161
G
R
V
K
D
I
Q
S
V
Y
L
D
T
T
F
Site 16
Y163
V
K
D
I
Q
S
V
Y
L
D
T
T
F
C
D
Site 17
T167
Q
S
V
Y
L
D
T
T
F
C
D
P
R
F
Y
Site 18
Y174
T
F
C
D
P
R
F
Y
Q
I
P
S
R
E
E
Site 19
S178
P
R
F
Y
Q
I
P
S
R
E
E
C
L
S
G
Site 20
S184
P
S
R
E
E
C
L
S
G
V
L
E
L
V
R
Site 21
S192
G
V
L
E
L
V
R
S
W
I
T
R
S
P
Y
Site 22
Y214
K
A
A
Y
G
Y
E
Y
L
F
T
N
L
S
E
Site 23
T217
Y
G
Y
E
Y
L
F
T
N
L
S
E
E
L
G
Site 24
T246
P
E
I
L
H
H
L
T
T
D
R
N
T
Q
I
Site 25
T247
E
I
L
H
H
L
T
T
D
R
N
T
Q
I
H
Site 26
Y264
R
H
P
K
A
E
E
Y
F
Q
W
S
K
L
P
Site 27
T275
S
K
L
P
C
G
I
T
S
R
N
R
I
P
L
Site 28
T291
I
I
S
I
K
P
S
T
M
W
F
G
E
R
S
Site 29
T301
F
G
E
R
S
R
K
T
N
V
I
V
R
T
G
Site 30
S310
V
I
V
R
T
G
E
S
S
Y
R
A
C
F
S
Site 31
S311
I
V
R
T
G
E
S
S
Y
R
A
C
F
S
F
Site 32
Y312
V
R
T
G
E
S
S
Y
R
A
C
F
S
F
H
Site 33
S317
S
S
Y
R
A
C
F
S
F
H
S
S
Y
S
E
Site 34
S321
A
C
F
S
F
H
S
S
Y
S
E
I
K
D
F
Site 35
S323
F
S
F
H
S
S
Y
S
E
I
K
D
F
L
S
Site 36
S362
L
K
P
L
C
R
S
S
Q
S
T
E
P
K
Y
Site 37
T365
L
C
R
S
S
Q
S
T
E
P
K
Y
K
P
L
Site 38
Y369
S
Q
S
T
E
P
K
Y
K
P
L
G
K
L
K
Site 39
T380
G
K
L
K
R
A
R
T
V
H
R
D
S
E
E
Site 40
S385
A
R
T
V
H
R
D
S
E
E
E
D
D
Y
L
Site 41
Y391
D
S
E
E
E
D
D
Y
L
F
D
D
P
L
P
Site 42
Y407
P
L
R
H
K
V
P
Y
P
E
T
F
H
P
E
Site 43
T410
H
K
V
P
Y
P
E
T
F
H
P
E
V
F
S
Site 44
S417
T
F
H
P
E
V
F
S
M
T
A
V
S
E
K
Site 45
T432
Q
P
E
K
L
R
Q
T
P
G
C
C
R
A
E
Site 46
S455
N
F
V
D
C
E
E
S
N
S
E
S
E
E
E
Site 47
S457
V
D
C
E
E
S
N
S
E
S
E
E
E
V
G
Site 48
S459
C
E
E
S
N
S
E
S
E
E
E
V
G
I
P
Site 49
S468
E
E
V
G
I
P
A
S
L
Q
G
D
L
G
S
Site 50
S475
S
L
Q
G
D
L
G
S
V
L
H
L
Q
K
A
Site 51
T500
F
K
R
N
D
E
I
T
D
E
S
L
E
N
F
Site 52
S503
N
D
E
I
T
D
E
S
L
E
N
F
P
S
S
Site 53
S509
E
S
L
E
N
F
P
S
S
T
V
A
G
G
S
Site 54
S510
S
L
E
N
F
P
S
S
T
V
A
G
G
S
Q
Site 55
T511
L
E
N
F
P
S
S
T
V
A
G
G
S
Q
S
Site 56
S516
S
S
T
V
A
G
G
S
Q
S
P
K
L
F
S
Site 57
S518
T
V
A
G
G
S
Q
S
P
K
L
F
S
D
S
Site 58
S523
S
Q
S
P
K
L
F
S
D
S
D
G
E
S
T
Site 59
S525
S
P
K
L
F
S
D
S
D
G
E
S
T
H
I
Site 60
S529
F
S
D
S
D
G
E
S
T
H
I
S
S
Q
N
Site 61
T530
S
D
S
D
G
E
S
T
H
I
S
S
Q
N
S
Site 62
S533
D
G
E
S
T
H
I
S
S
Q
N
S
S
Q
S
Site 63
S534
G
E
S
T
H
I
S
S
Q
N
S
S
Q
S
T
Site 64
S537
T
H
I
S
S
Q
N
S
S
Q
S
T
H
I
T
Site 65
S538
H
I
S
S
Q
N
S
S
Q
S
T
H
I
T
E
Site 66
S540
S
S
Q
N
S
S
Q
S
T
H
I
T
E
Q
G
Site 67
T541
S
Q
N
S
S
Q
S
T
H
I
T
E
Q
G
S
Site 68
T544
S
S
Q
S
T
H
I
T
E
Q
G
S
Q
G
W
Site 69
S548
T
H
I
T
E
Q
G
S
Q
G
W
D
S
Q
S
Site 70
S553
Q
G
S
Q
G
W
D
S
Q
S
D
T
V
L
L
Site 71
S555
S
Q
G
W
D
S
Q
S
D
T
V
L
L
S
S
Site 72
T557
G
W
D
S
Q
S
D
T
V
L
L
S
S
Q
E
Site 73
S561
Q
S
D
T
V
L
L
S
S
Q
E
R
N
S
G
Site 74
S562
S
D
T
V
L
L
S
S
Q
E
R
N
S
G
D
Site 75
S567
L
S
S
Q
E
R
N
S
G
D
I
T
S
L
D
Site 76
T571
E
R
N
S
G
D
I
T
S
L
D
K
A
D
Y
Site 77
S572
R
N
S
G
D
I
T
S
L
D
K
A
D
Y
R
Site 78
Y578
T
S
L
D
K
A
D
Y
R
P
T
I
K
E
N
Site 79
T581
D
K
A
D
Y
R
P
T
I
K
E
N
I
P
A
Site 80
T601
N
V
I
C
P
K
D
T
Y
S
D
L
K
S
R
Site 81
Y602
V
I
C
P
K
D
T
Y
S
D
L
K
S
R
D
Site 82
S603
I
C
P
K
D
T
Y
S
D
L
K
S
R
D
K
Site 83
S607
D
T
Y
S
D
L
K
S
R
D
K
D
V
T
I
Site 84
T613
K
S
R
D
K
D
V
T
I
V
P
S
T
G
E
Site 85
T618
D
V
T
I
V
P
S
T
G
E
P
T
T
L
S
Site 86
T623
P
S
T
G
E
P
T
T
L
S
S
E
T
H
I
Site 87
S625
T
G
E
P
T
T
L
S
S
E
T
H
I
P
E
Site 88
S626
G
E
P
T
T
L
S
S
E
T
H
I
P
E
E
Site 89
S635
T
H
I
P
E
E
K
S
L
L
N
L
S
T
N
Site 90
S640
E
K
S
L
L
N
L
S
T
N
A
D
S
Q
S
Site 91
T641
K
S
L
L
N
L
S
T
N
A
D
S
Q
S
S
Site 92
S645
N
L
S
T
N
A
D
S
Q
S
S
S
D
F
E
Site 93
S647
S
T
N
A
D
S
Q
S
S
S
D
F
E
V
P
Site 94
S649
N
A
D
S
Q
S
S
S
D
F
E
V
P
S
T
Site 95
S655
S
S
D
F
E
V
P
S
T
P
E
A
E
L
P
Site 96
T656
S
D
F
E
V
P
S
T
P
E
A
E
L
P
K
Site 97
Y669
P
K
R
E
H
L
Q
Y
L
Y
E
K
L
A
T
Site 98
Y671
R
E
H
L
Q
Y
L
Y
E
K
L
A
T
G
E
Site 99
T676
Y
L
Y
E
K
L
A
T
G
E
S
I
A
V
K
Site 100
S679
E
K
L
A
T
G
E
S
I
A
V
K
K
R
K
Site 101
S688
A
V
K
K
R
K
C
S
L
L
D
T
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation