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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMEM209
Full Name:
Transmembrane protein 209
Alias:
Transmembrane protein 209: Transmembrane protein 209: Transmembrane protein 209: Transmembrane protein 209
Type:
Mass (Da):
62922
Number AA:
561
UniProt ID:
Q96SK2
International Prot ID:
IPI00045764
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016020
GO:0016021
GO:0031224
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
M
Q
G
E
A
H
P
S
A
S
L
I
D
R
T
Site 2
S11
G
E
A
H
P
S
A
S
L
I
D
R
T
I
K
Site 3
T23
T
I
K
M
R
K
E
T
E
A
R
K
V
V
L
Site 4
Y55
T
G
K
L
I
S
S
Y
Y
N
V
T
Y
W
P
Site 5
Y56
G
K
L
I
S
S
Y
Y
N
V
T
Y
W
P
L
Site 6
Y60
S
S
Y
Y
N
V
T
Y
W
P
L
W
Y
I
E
Site 7
Y88
D
F
W
R
Y
F
K
Y
T
V
A
P
T
S
L
Site 8
S98
A
P
T
S
L
V
V
S
P
G
Q
Q
T
L
L
Site 9
T103
V
V
S
P
G
Q
Q
T
L
L
G
L
K
T
A
Site 10
T115
K
T
A
V
V
Q
T
T
P
P
H
D
L
A
A
Site 11
T123
P
P
H
D
L
A
A
T
Q
I
P
P
A
P
P
Site 12
S131
Q
I
P
P
A
P
P
S
P
S
I
Q
G
Q
S
Site 13
S133
P
P
A
P
P
S
P
S
I
Q
G
Q
S
V
L
Site 14
S138
S
P
S
I
Q
G
Q
S
V
L
S
Y
S
P
S
Site 15
S141
I
Q
G
Q
S
V
L
S
Y
S
P
S
R
S
P
Site 16
Y142
Q
G
Q
S
V
L
S
Y
S
P
S
R
S
P
S
Site 17
S143
G
Q
S
V
L
S
Y
S
P
S
R
S
P
S
T
Site 18
S145
S
V
L
S
Y
S
P
S
R
S
P
S
T
S
P
Site 19
S147
L
S
Y
S
P
S
R
S
P
S
T
S
P
K
F
Site 20
S149
Y
S
P
S
R
S
P
S
T
S
P
K
F
T
T
Site 21
T150
S
P
S
R
S
P
S
T
S
P
K
F
T
T
S
Site 22
S151
P
S
R
S
P
S
T
S
P
K
F
T
T
S
C
Site 23
T155
P
S
T
S
P
K
F
T
T
S
C
M
T
G
Y
Site 24
T156
S
T
S
P
K
F
T
T
S
C
M
T
G
Y
S
Site 25
S157
T
S
P
K
F
T
T
S
C
M
T
G
Y
S
P
Site 26
S163
T
S
C
M
T
G
Y
S
P
Q
L
Q
G
L
S
Site 27
S170
S
P
Q
L
Q
G
L
S
S
G
G
S
G
S
Y
Site 28
S171
P
Q
L
Q
G
L
S
S
G
G
S
G
S
Y
S
Site 29
S174
Q
G
L
S
S
G
G
S
G
S
Y
S
P
G
V
Site 30
S176
L
S
S
G
G
S
G
S
Y
S
P
G
V
T
Y
Site 31
S178
S
G
G
S
G
S
Y
S
P
G
V
T
Y
S
P
Site 32
T182
G
S
Y
S
P
G
V
T
Y
S
P
V
S
G
Y
Site 33
Y183
S
Y
S
P
G
V
T
Y
S
P
V
S
G
Y
N
Site 34
S184
Y
S
P
G
V
T
Y
S
P
V
S
G
Y
N
K
Site 35
S187
G
V
T
Y
S
P
V
S
G
Y
N
K
L
A
S
Site 36
Y189
T
Y
S
P
V
S
G
Y
N
K
L
A
S
F
S
Site 37
S194
S
G
Y
N
K
L
A
S
F
S
P
S
P
P
S
Site 38
S196
Y
N
K
L
A
S
F
S
P
S
P
P
S
P
Y
Site 39
S198
K
L
A
S
F
S
P
S
P
P
S
P
Y
P
T
Site 40
S201
S
F
S
P
S
P
P
S
P
Y
P
T
T
V
G
Site 41
Y203
S
P
S
P
P
S
P
Y
P
T
T
V
G
P
V
Site 42
T205
S
P
P
S
P
Y
P
T
T
V
G
P
V
E
S
Site 43
T206
P
P
S
P
Y
P
T
T
V
G
P
V
E
S
S
Site 44
S213
T
V
G
P
V
E
S
S
G
L
R
S
R
Y
R
Site 45
S217
V
E
S
S
G
L
R
S
R
Y
R
S
S
P
T
Site 46
Y219
S
S
G
L
R
S
R
Y
R
S
S
P
T
V
Y
Site 47
S221
G
L
R
S
R
Y
R
S
S
P
T
V
Y
N
S
Site 48
S222
L
R
S
R
Y
R
S
S
P
T
V
Y
N
S
P
Site 49
T224
S
R
Y
R
S
S
P
T
V
Y
N
S
P
T
D
Site 50
Y226
Y
R
S
S
P
T
V
Y
N
S
P
T
D
K
E
Site 51
S228
S
S
P
T
V
Y
N
S
P
T
D
K
E
D
Y
Site 52
T230
P
T
V
Y
N
S
P
T
D
K
E
D
Y
M
T
Site 53
Y235
S
P
T
D
K
E
D
Y
M
T
D
L
R
T
L
Site 54
T237
T
D
K
E
D
Y
M
T
D
L
R
T
L
D
T
Site 55
T241
D
Y
M
T
D
L
R
T
L
D
T
F
L
R
S
Site 56
T244
T
D
L
R
T
L
D
T
F
L
R
S
E
E
E
Site 57
S248
T
L
D
T
F
L
R
S
E
E
E
K
Q
H
R
Site 58
S260
Q
H
R
V
K
L
G
S
P
D
S
T
S
P
S
Site 59
S263
V
K
L
G
S
P
D
S
T
S
P
S
S
S
P
Site 60
T264
K
L
G
S
P
D
S
T
S
P
S
S
S
P
T
Site 61
S265
L
G
S
P
D
S
T
S
P
S
S
S
P
T
F
Site 62
S267
S
P
D
S
T
S
P
S
S
S
P
T
F
W
N
Site 63
S268
P
D
S
T
S
P
S
S
S
P
T
F
W
N
Y
Site 64
S269
D
S
T
S
P
S
S
S
P
T
F
W
N
Y
S
Site 65
T271
T
S
P
S
S
S
P
T
F
W
N
Y
S
R
S
Site 66
Y275
S
S
P
T
F
W
N
Y
S
R
S
M
G
D
Y
Site 67
Y282
Y
S
R
S
M
G
D
Y
A
Q
T
L
K
K
F
Site 68
T285
S
M
G
D
Y
A
Q
T
L
K
K
F
Q
Y
Q
Site 69
Y291
Q
T
L
K
K
F
Q
Y
Q
L
A
C
R
S
Q
Site 70
S310
N
K
D
E
A
D
L
S
S
K
Q
A
A
E
E
Site 71
T360
Q
E
I
E
S
V
S
T
Q
M
R
R
M
G
C
Site 72
Y400
T
L
N
T
I
V
Q
Y
L
D
L
T
P
N
Q
Site 73
T404
I
V
Q
Y
L
D
L
T
P
N
Q
E
Y
L
F
Site 74
S418
F
E
R
I
K
E
L
S
Q
G
G
C
M
S
S
Site 75
S425
S
Q
G
G
C
M
S
S
F
R
W
N
R
G
G
Site 76
T441
F
K
G
R
K
W
D
T
D
L
P
T
D
S
A
Site 77
S460
V
F
C
T
Y
L
D
S
R
L
P
P
H
P
K
Site 78
Y468
R
L
P
P
H
P
K
Y
P
D
G
K
T
F
T
Site 79
T473
P
K
Y
P
D
G
K
T
F
T
S
Q
H
F
V
Site 80
S476
P
D
G
K
T
F
T
S
Q
H
F
V
Q
T
P
Site 81
T482
T
S
Q
H
F
V
Q
T
P
N
K
P
D
V
T
Site 82
T489
T
P
N
K
P
D
V
T
N
E
N
V
F
C
I
Site 83
Y497
N
E
N
V
F
C
I
Y
Q
S
A
I
N
P
P
Site 84
Y506
S
A
I
N
P
P
H
Y
E
L
I
Y
Q
R
H
Site 85
Y510
P
P
H
Y
E
L
I
Y
Q
R
H
V
Y
N
L
Site 86
Y515
L
I
Y
Q
R
H
V
Y
N
L
P
K
G
R
N
Site 87
T537
M
F
L
Y
I
I
K
T
K
E
S
G
M
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation