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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CPXM1
Full Name:
Probable carboxypeptidase X1
Alias:
Metallocarboxypeptidase CPX-1
Type:
Mass (Da):
81668
Number AA:
734
UniProt ID:
Q96SM3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T34
L
G
L
A
Q
P
G
T
T
K
V
P
G
S
T
Site 2
T35
G
L
A
Q
P
G
T
T
K
V
P
G
S
T
P
Site 3
S40
G
T
T
K
V
P
G
S
T
P
A
L
H
S
S
Site 4
T41
T
T
K
V
P
G
S
T
P
A
L
H
S
S
P
Site 5
S46
G
S
T
P
A
L
H
S
S
P
A
Q
P
P
A
Site 6
S47
S
T
P
A
L
H
S
S
P
A
Q
P
P
A
E
Site 7
T83
M
K
K
R
K
K
L
T
L
T
R
P
T
P
L
Site 8
T113
D
P
A
E
K
Q
E
T
G
C
P
P
L
G
L
Site 9
S122
C
P
P
L
G
L
E
S
L
R
V
S
D
S
R
Site 10
S126
G
L
E
S
L
R
V
S
D
S
R
L
E
A
S
Site 11
S128
E
S
L
R
V
S
D
S
R
L
E
A
S
S
S
Site 12
S133
S
D
S
R
L
E
A
S
S
S
Q
S
F
G
L
Site 13
S134
D
S
R
L
E
A
S
S
S
Q
S
F
G
L
G
Site 14
S135
S
R
L
E
A
S
S
S
Q
S
F
G
L
G
P
Site 15
S137
L
E
A
S
S
S
Q
S
F
G
L
G
P
H
R
Site 16
S151
R
G
R
L
N
I
Q
S
G
L
E
D
G
D
L
Site 17
Y159
G
L
E
D
G
D
L
Y
D
G
A
W
C
A
E
Site 18
S185
A
G
H
P
T
R
F
S
G
V
I
T
Q
G
R
Site 19
T189
T
R
F
S
G
V
I
T
Q
G
R
N
S
V
W
Site 20
Y198
G
R
N
S
V
W
R
Y
D
W
V
T
S
Y
K
Site 21
Y204
R
Y
D
W
V
T
S
Y
K
V
Q
F
S
N
D
Site 22
S212
K
V
Q
F
S
N
D
S
R
T
W
W
G
S
R
Site 23
S233
D
A
V
F
P
A
N
S
D
P
E
T
P
V
L
Site 24
T237
P
A
N
S
D
P
E
T
P
V
L
N
L
L
P
Site 25
S289
L
F
L
E
A
P
A
S
G
S
S
D
P
L
D
Site 26
S291
L
E
A
P
A
S
G
S
S
D
P
L
D
F
Q
Site 27
Y323
C
P
N
I
T
R
I
Y
S
I
G
K
S
Y
Q
Site 28
S324
P
N
I
T
R
I
Y
S
I
G
K
S
Y
Q
G
Site 29
S328
R
I
Y
S
I
G
K
S
Y
Q
G
L
K
L
Y
Site 30
Y329
I
Y
S
I
G
K
S
Y
Q
G
L
K
L
Y
V
Site 31
Y335
S
Y
Q
G
L
K
L
Y
V
M
E
M
S
D
K
Site 32
S340
K
L
Y
V
M
E
M
S
D
K
P
G
E
H
E
Site 33
Y355
L
G
E
P
E
V
R
Y
V
A
G
M
H
G
N
Site 34
T389
L
R
G
N
P
R
V
T
R
L
L
S
E
M
R
Site 35
Y408
P
S
M
N
P
D
G
Y
E
I
A
Y
H
R
G
Site 36
Y412
P
D
G
Y
E
I
A
Y
H
R
G
S
E
L
V
Site 37
S416
E
I
A
Y
H
R
G
S
E
L
V
G
W
A
E
Site 38
T442
H
N
F
A
D
L
N
T
P
L
W
E
A
Q
D
Site 39
Y467
H
H
L
P
L
P
T
Y
Y
T
L
P
N
A
T
Site 40
T474
Y
Y
T
L
P
N
A
T
V
A
P
E
T
R
A
Site 41
S494
K
R
I
P
F
V
L
S
A
N
L
H
G
G
E
Site 42
S505
H
G
G
E
L
V
V
S
Y
P
F
D
M
T
R
Site 43
Y506
G
G
E
L
V
V
S
Y
P
F
D
M
T
R
T
Site 44
T511
V
S
Y
P
F
D
M
T
R
T
P
W
A
A
R
Site 45
T513
Y
P
F
D
M
T
R
T
P
W
A
A
R
E
L
Site 46
T521
P
W
A
A
R
E
L
T
P
T
P
D
D
A
V
Site 47
T523
A
A
R
E
L
T
P
T
P
D
D
A
V
F
R
Site 48
T546
S
N
L
A
M
Q
D
T
S
R
R
P
C
H
S
Site 49
S547
N
L
A
M
Q
D
T
S
R
R
P
C
H
S
Q
Site 50
S553
T
S
R
R
P
C
H
S
Q
D
F
S
V
H
G
Site 51
T570
I
N
G
A
D
W
H
T
V
P
G
S
M
N
D
Site 52
Y580
G
S
M
N
D
F
S
Y
L
H
T
N
C
F
E
Site 53
S593
F
E
V
T
V
E
L
S
C
D
K
F
P
H
E
Site 54
Y617
N
K
D
A
L
L
T
Y
L
E
Q
V
R
M
G
Site 55
T634
G
V
V
R
D
K
D
T
E
L
G
I
A
D
A
Site 56
Y660
T
T
A
W
G
G
D
Y
W
R
L
L
T
P
G
Site 57
T665
G
D
Y
W
R
L
L
T
P
G
D
Y
M
V
T
Site 58
Y669
R
L
L
T
P
G
D
Y
M
V
T
A
S
A
E
Site 59
T672
T
P
G
D
Y
M
V
T
A
S
A
E
G
Y
H
Site 60
S674
G
D
Y
M
V
T
A
S
A
E
G
Y
H
S
V
Site 61
Y678
V
T
A
S
A
E
G
Y
H
S
V
T
R
N
C
Site 62
S680
A
S
A
E
G
Y
H
S
V
T
R
N
C
R
V
Site 63
T682
A
E
G
Y
H
S
V
T
R
N
C
R
V
T
F
Site 64
T688
V
T
R
N
C
R
V
T
F
E
E
G
P
F
P
Site 65
T703
C
N
F
V
L
T
K
T
P
K
Q
R
L
R
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation