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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATOH8
Full Name:
Protein atonal homolog 8
Alias:
Class A basic helix-loop-helix protein 21;Helix-loop-helix protein hATH-6
Type:
Mass (Da):
34644
Number AA:
321
UniProt ID:
Q96SQ7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
L
E
D
G
P
W
K
T
V
C
V
K
E
L
N
Site 2
Y40
P
A
R
R
A
N
G
Y
K
T
F
R
L
D
L
Site 3
T42
R
R
A
N
G
Y
K
T
F
R
L
D
L
E
A
Site 4
T64
T
N
G
L
R
D
R
T
H
R
L
Q
P
V
P
Site 5
T90
A
V
P
P
R
G
G
T
D
T
A
G
E
R
G
Site 6
T92
P
P
R
G
G
T
D
T
A
G
E
R
G
G
S
Site 7
S99
T
A
G
E
R
G
G
S
R
A
P
E
V
S
D
Site 8
S105
G
S
R
A
P
E
V
S
D
A
R
K
R
C
F
Site 9
T123
A
V
G
P
G
L
P
T
P
P
P
P
P
P
P
Site 10
S134
P
P
P
P
A
P
Q
S
Q
A
P
G
G
P
E
Site 11
S166
P
P
A
R
P
A
P
S
A
P
P
A
P
P
A
Site 12
S177
A
P
P
A
P
P
E
S
T
V
R
P
A
P
P
Site 13
T178
P
P
A
P
P
E
S
T
V
R
P
A
P
P
T
Site 14
T185
T
V
R
P
A
P
P
T
R
P
G
E
S
S
Y
Site 15
S190
P
P
T
R
P
G
E
S
S
Y
S
S
I
S
H
Site 16
S191
P
T
R
P
G
E
S
S
Y
S
S
I
S
H
V
Site 17
Y192
T
R
P
G
E
S
S
Y
S
S
I
S
H
V
I
Site 18
S193
R
P
G
E
S
S
Y
S
S
I
S
H
V
I
Y
Site 19
S194
P
G
E
S
S
Y
S
S
I
S
H
V
I
Y
N
Site 20
S196
E
S
S
Y
S
S
I
S
H
V
I
Y
N
N
H
Site 21
Y200
S
S
I
S
H
V
I
Y
N
N
H
Q
D
S
S
Site 22
S207
Y
N
N
H
Q
D
S
S
A
S
P
R
K
R
P
Site 23
S209
N
H
Q
D
S
S
A
S
P
R
K
R
P
G
E
Site 24
T218
R
K
R
P
G
E
A
T
A
A
S
S
E
I
K
Site 25
T241
L
A
N
A
R
E
R
T
R
V
H
T
I
S
A
Site 26
T245
R
E
R
T
R
V
H
T
I
S
A
A
F
E
A
Site 27
S247
R
T
R
V
H
T
I
S
A
A
F
E
A
L
R
Site 28
Y260
L
R
K
Q
V
P
C
Y
S
Y
G
Q
K
L
S
Site 29
S261
R
K
Q
V
P
C
Y
S
Y
G
Q
K
L
S
K
Site 30
S267
Y
S
Y
G
Q
K
L
S
K
L
A
I
L
R
I
Site 31
Y278
I
L
R
I
A
C
N
Y
I
L
S
L
A
R
L
Site 32
Y290
A
R
L
A
D
L
D
Y
S
A
D
H
S
N
L
Site 33
S291
R
L
A
D
L
D
Y
S
A
D
H
S
N
L
S
Site 34
S295
L
D
Y
S
A
D
H
S
N
L
S
F
S
E
C
Site 35
S298
S
A
D
H
S
N
L
S
F
S
E
C
V
Q
R
Site 36
T307
S
E
C
V
Q
R
C
T
R
T
L
Q
A
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation