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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CYP2S1
Full Name:
Cytochrome P450 2S1
Alias:
CYPIIS1
Type:
Mass (Da):
55817
Number AA:
504
UniProt ID:
Q96SQ9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T37
G
H
L
P
P
G
P
T
P
L
P
L
L
G
N
Site 2
Y54
Q
L
R
P
G
A
L
Y
S
G
L
M
R
L
S
Site 3
S55
L
R
P
G
A
L
Y
S
G
L
M
R
L
S
K
Site 4
S61
Y
S
G
L
M
R
L
S
K
K
Y
G
P
V
F
Site 5
S99
G
G
Q
A
E
E
F
S
G
R
G
T
V
A
M
Site 6
T103
E
E
F
S
G
R
G
T
V
A
M
L
E
G
T
Site 7
T131
W
R
Q
L
R
K
F
T
M
L
A
L
R
D
L
Site 8
T159
E
A
R
C
L
V
E
T
F
Q
G
T
E
G
R
Site 9
S171
E
G
R
P
F
D
P
S
L
L
L
A
Q
A
T
Site 10
S192
L
L
F
G
L
R
F
S
Y
E
D
K
E
F
Q
Site 11
Y193
L
F
G
L
R
F
S
Y
E
D
K
E
F
Q
A
Site 12
S213
G
G
T
L
L
G
V
S
S
Q
G
G
Q
T
Y
Site 13
S214
G
T
L
L
G
V
S
S
Q
G
G
Q
T
Y
E
Site 14
Y220
S
S
Q
G
G
Q
T
Y
E
M
F
S
W
F
L
Site 15
S262
H
Q
G
N
L
D
A
S
G
P
A
R
D
L
V
Site 16
T295
T
N
K
N
M
L
M
T
V
I
Y
L
L
F
A
Site 17
S343
L
G
A
G
Q
A
P
S
L
G
D
R
T
R
L
Site 18
T348
A
P
S
L
G
D
R
T
R
L
P
Y
T
D
A
Site 19
Y352
G
D
R
T
R
L
P
Y
T
D
A
V
L
H
E
Site 20
T353
D
R
T
R
L
P
Y
T
D
A
V
L
H
E
A
Site 21
T374
V
P
M
G
I
P
R
T
L
M
R
T
T
R
F
Site 22
T378
I
P
R
T
L
M
R
T
T
R
F
R
G
Y
T
Site 23
T379
P
R
T
L
M
R
T
T
R
F
R
G
Y
T
L
Site 24
Y384
R
T
T
R
F
R
G
Y
T
L
P
Q
G
T
E
Site 25
T385
T
T
R
F
R
G
Y
T
L
P
Q
G
T
E
V
Site 26
S465
L
Q
A
F
S
L
E
S
P
C
P
P
D
T
L
Site 27
T471
E
S
P
C
P
P
D
T
L
S
L
K
P
T
V
Site 28
S473
P
C
P
P
D
T
L
S
L
K
P
T
V
S
G
Site 29
T495
F
Q
L
Q
V
R
P
T
D
L
H
S
T
T
Q
Site 30
S499
V
R
P
T
D
L
H
S
T
T
Q
T
R
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation