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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDK5RAP1
Full Name:
CDK5 regulatory subunit-associated protein 1
Alias:
CDK5 activator-binding protein C42
Type:
Mass (Da):
67670
Number AA:
601
UniProt ID:
Q96SZ6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0051539
GO:0005506
GO:0042808
PhosphoSite+
KinaseNET
Biological Process:
GO:0007420
GO:0045736
GO:0045664
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
L
R
M
C
R
A
H
S
S
L
S
S
T
M
C
Site 2
S35
R
M
C
R
A
H
S
S
L
S
S
T
M
C
P
Site 3
S37
C
R
A
H
S
S
L
S
S
T
M
C
P
S
P
Site 4
S38
R
A
H
S
S
L
S
S
T
M
C
P
S
P
E
Site 5
T39
A
H
S
S
L
S
S
T
M
C
P
S
P
E
R
Site 6
S43
L
S
S
T
M
C
P
S
P
E
R
Q
E
D
G
Site 7
S56
D
G
A
R
K
D
F
S
S
R
L
A
A
G
P
Site 8
S57
G
A
R
K
D
F
S
S
R
L
A
A
G
P
T
Site 9
T64
S
R
L
A
A
G
P
T
F
Q
H
F
L
K
S
Site 10
S71
T
F
Q
H
F
L
K
S
A
S
A
P
Q
E
K
Site 11
S73
Q
H
F
L
K
S
A
S
A
P
Q
E
K
L
S
Site 12
S80
S
A
P
Q
E
K
L
S
S
E
V
E
D
P
P
Site 13
S81
A
P
Q
E
K
L
S
S
E
V
E
D
P
P
P
Site 14
Y89
E
V
E
D
P
P
P
Y
L
M
M
D
E
L
L
Site 15
Y103
L
G
R
Q
R
K
V
Y
L
E
T
Y
G
C
Q
Site 16
Y107
R
K
V
Y
L
E
T
Y
G
C
Q
M
N
V
N
Site 17
S126
A
W
S
I
L
Q
K
S
G
Y
L
R
T
S
N
Site 18
Y128
S
I
L
Q
K
S
G
Y
L
R
T
S
N
L
Q
Site 19
S132
K
S
G
Y
L
R
T
S
N
L
Q
E
A
D
V
Site 20
T167
H
Q
L
K
A
L
K
T
R
R
P
R
S
R
V
Site 21
S172
L
K
T
R
R
P
R
S
R
V
P
L
R
I
G
Site 22
S230
Q
A
A
N
V
L
L
S
L
D
E
T
Y
A
D
Site 23
T270
S
Y
C
I
V
P
F
T
R
G
R
E
R
S
R
Site 24
S276
F
T
R
G
R
E
R
S
R
P
I
A
S
I
L
Site 25
S320
L
L
G
Q
N
V
N
S
F
R
D
N
S
E
V
Site 26
S325
V
N
S
F
R
D
N
S
E
V
Q
F
N
S
A
Site 27
S331
N
S
E
V
Q
F
N
S
A
V
P
T
N
L
S
Site 28
T335
Q
F
N
S
A
V
P
T
N
L
S
R
G
F
T
Site 29
S338
S
A
V
P
T
N
L
S
R
G
F
T
T
N
Y
Site 30
T342
T
N
L
S
R
G
F
T
T
N
Y
K
T
K
Q
Site 31
Y345
S
R
G
F
T
T
N
Y
K
T
K
Q
G
G
L
Site 32
T347
G
F
T
T
N
Y
K
T
K
Q
G
G
L
R
F
Site 33
S362
A
H
L
L
D
Q
V
S
R
V
D
P
E
M
R
Site 34
T373
P
E
M
R
I
R
F
T
S
P
H
P
K
D
F
Site 35
S374
E
M
R
I
R
F
T
S
P
H
P
K
D
F
P
Site 36
S404
Q
I
H
L
P
A
Q
S
G
S
S
R
V
L
E
Site 37
S406
H
L
P
A
Q
S
G
S
S
R
V
L
E
A
M
Site 38
Y417
L
E
A
M
R
R
G
Y
S
R
E
A
Y
V
E
Site 39
S418
E
A
M
R
R
G
Y
S
R
E
A
Y
V
E
L
Site 40
Y422
R
G
Y
S
R
E
A
Y
V
E
L
V
H
H
I
Site 41
S459
E
D
H
V
Q
T
V
S
L
L
R
E
V
Q
Y
Site 42
Y474
N
M
G
F
L
F
A
Y
S
M
R
Q
K
T
R
Site 43
T480
A
Y
S
M
R
Q
K
T
R
A
Y
H
R
L
K
Site 44
Y483
M
R
Q
K
T
R
A
Y
H
R
L
K
D
D
V
Site 45
T504
R
R
L
E
E
L
I
T
I
F
R
E
E
A
T
Site 46
S533
V
E
G
L
S
K
R
S
A
T
D
L
C
G
R
Site 47
T535
G
L
S
K
R
S
A
T
D
L
C
G
R
N
D
Site 48
S581
V
K
I
T
S
A
S
S
Q
T
L
R
G
H
V
Site 49
T592
R
G
H
V
L
C
R
T
T
L
R
D
S
S
A
Site 50
T593
G
H
V
L
C
R
T
T
L
R
D
S
S
A
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation