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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SECISBP2
Full Name:
Selenocysteine insertion sequence-binding protein 2
Alias:
Sebp2; Secis-binding protein 2; Selenocysteine insertion sequence-binding protein 2
Type:
Translation
Mass (Da):
95462
Number AA:
854
UniProt ID:
Q96T21
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003730
PhosphoSite+
KinaseNET
Biological Process:
GO:0006412
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
E
G
P
R
E
P
E
S
E
G
I
K
L
S
A
Site 2
S17
E
S
E
G
I
K
L
S
A
D
V
K
P
F
V
Site 3
Y50
F
P
S
S
A
A
T
Y
Y
P
F
V
Q
E
P
Site 4
Y51
P
S
S
A
A
T
Y
Y
P
F
V
Q
E
P
P
Site 5
T60
F
V
Q
E
P
P
V
T
E
Q
K
I
Y
T
E
Site 6
Y65
P
V
T
E
Q
K
I
Y
T
E
D
M
A
F
G
Site 7
T75
D
M
A
F
G
A
S
T
F
P
P
Q
Y
L
S
Site 8
Y80
A
S
T
F
P
P
Q
Y
L
S
S
E
I
T
L
Site 9
S82
T
F
P
P
Q
Y
L
S
S
E
I
T
L
H
P
Site 10
S83
F
P
P
Q
Y
L
S
S
E
I
T
L
H
P
Y
Site 11
T86
Q
Y
L
S
S
E
I
T
L
H
P
Y
A
Y
S
Site 12
Y90
S
E
I
T
L
H
P
Y
A
Y
S
P
Y
T
L
Site 13
S93
T
L
H
P
Y
A
Y
S
P
Y
T
L
D
S
T
Site 14
Y95
H
P
Y
A
Y
S
P
Y
T
L
D
S
T
Q
N
Site 15
T96
P
Y
A
Y
S
P
Y
T
L
D
S
T
Q
N
V
Site 16
S99
Y
S
P
Y
T
L
D
S
T
Q
N
V
Y
S
V
Site 17
T100
S
P
Y
T
L
D
S
T
Q
N
V
Y
S
V
P
Site 18
Y104
L
D
S
T
Q
N
V
Y
S
V
P
G
S
Q
Y
Site 19
S105
D
S
T
Q
N
V
Y
S
V
P
G
S
Q
Y
L
Site 20
S109
N
V
Y
S
V
P
G
S
Q
Y
L
Y
N
Q
P
Site 21
Y111
Y
S
V
P
G
S
Q
Y
L
Y
N
Q
P
S
C
Site 22
Y113
V
P
G
S
Q
Y
L
Y
N
Q
P
S
C
Y
R
Site 23
T147
K
A
L
F
K
K
K
T
Y
D
E
K
K
T
Y
Site 24
Y154
T
Y
D
E
K
K
T
Y
D
Q
Q
K
F
D
S
Site 25
S161
Y
D
Q
Q
K
F
D
S
E
R
A
D
G
T
I
Site 26
T167
D
S
E
R
A
D
G
T
I
S
S
E
I
K
S
Site 27
S169
E
R
A
D
G
T
I
S
S
E
I
K
S
A
R
Site 28
S170
R
A
D
G
T
I
S
S
E
I
K
S
A
R
G
Site 29
S174
T
I
S
S
E
I
K
S
A
R
G
S
H
H
L
Site 30
S178
E
I
K
S
A
R
G
S
H
H
L
S
I
Y
A
Site 31
S182
A
R
G
S
H
H
L
S
I
Y
A
E
N
S
L
Site 32
Y184
G
S
H
H
L
S
I
Y
A
E
N
S
L
K
S
Site 33
S188
L
S
I
Y
A
E
N
S
L
K
S
D
G
Y
H
Site 34
Y194
N
S
L
K
S
D
G
Y
H
K
R
T
D
R
K
Site 35
T198
S
D
G
Y
H
K
R
T
D
R
K
S
R
I
I
Site 36
S202
H
K
R
T
D
R
K
S
R
I
I
A
K
N
V
Site 37
S210
R
I
I
A
K
N
V
S
T
S
K
P
E
F
E
Site 38
S212
I
A
K
N
V
S
T
S
K
P
E
F
E
F
T
Site 39
T219
S
K
P
E
F
E
F
T
T
L
D
F
P
E
L
Site 40
S234
Q
G
A
E
N
N
M
S
E
I
Q
K
Q
P
K
Site 41
S247
P
K
W
G
P
V
H
S
V
S
T
D
I
S
L
Site 42
S279
V
K
N
N
P
N
E
S
V
T
A
N
A
A
T
Site 43
T286
S
V
T
A
N
A
A
T
N
S
P
S
C
T
R
Site 44
S288
T
A
N
A
A
T
N
S
P
S
C
T
R
E
L
Site 45
S290
N
A
A
T
N
S
P
S
C
T
R
E
L
S
W
Site 46
T292
A
T
N
S
P
S
C
T
R
E
L
S
W
T
P
Site 47
S296
P
S
C
T
R
E
L
S
W
T
P
M
G
Y
V
Site 48
T298
C
T
R
E
L
S
W
T
P
M
G
Y
V
V
R
Site 49
T307
M
G
Y
V
V
R
Q
T
L
S
T
E
L
S
A
Site 50
T310
V
V
R
Q
T
L
S
T
E
L
S
A
A
P
K
Site 51
S313
Q
T
L
S
T
E
L
S
A
A
P
K
N
V
T
Site 52
T327
T
S
M
I
N
L
K
T
I
A
S
S
A
D
P
Site 53
S330
I
N
L
K
T
I
A
S
S
A
D
P
K
N
V
Site 54
S338
S
A
D
P
K
N
V
S
I
P
S
S
E
A
L
Site 55
S341
P
K
N
V
S
I
P
S
S
E
A
L
S
S
D
Site 56
S342
K
N
V
S
I
P
S
S
E
A
L
S
S
D
P
Site 57
S346
I
P
S
S
E
A
L
S
S
D
P
S
Y
N
K
Site 58
S347
P
S
S
E
A
L
S
S
D
P
S
Y
N
K
E
Site 59
S350
E
A
L
S
S
D
P
S
Y
N
K
E
K
H
I
Site 60
Y351
A
L
S
S
D
P
S
Y
N
K
E
K
H
I
I
Site 61
S364
I
I
H
P
T
Q
K
S
K
A
S
Q
G
S
D
Site 62
S367
P
T
Q
K
S
K
A
S
Q
G
S
D
L
E
Q
Site 63
S388
N
K
K
K
K
E
K
S
T
S
K
Y
E
V
L
Site 64
S390
K
K
K
E
K
S
T
S
K
Y
E
V
L
T
V
Site 65
Y392
K
E
K
S
T
S
K
Y
E
V
L
T
V
Q
E
Site 66
T396
T
S
K
Y
E
V
L
T
V
Q
E
P
P
R
I
Site 67
S416
F
P
N
L
A
V
A
S
E
R
R
D
R
I
E
Site 68
T424
E
R
R
D
R
I
E
T
P
K
F
Q
S
K
Q
Site 69
S444
F
K
N
N
V
K
K
S
Q
L
P
V
Q
L
D
Site 70
S465
A
L
E
K
K
Q
H
S
Q
H
A
K
Q
S
S
Site 71
S472
S
Q
H
A
K
Q
S
S
K
P
V
V
V
S
V
Site 72
S499
G
E
R
G
R
R
M
S
Q
M
K
T
P
H
N
Site 73
T503
R
R
M
S
Q
M
K
T
P
H
N
P
L
D
S
Site 74
S510
T
P
H
N
P
L
D
S
S
A
P
L
M
K
K
Site 75
S511
P
H
N
P
L
D
S
S
A
P
L
M
K
K
G
Site 76
S531
P
K
A
K
K
P
T
S
L
K
K
I
I
L
K
Site 77
S553
R
L
Q
E
N
A
V
S
P
A
F
T
S
D
D
Site 78
T561
P
A
F
T
S
D
D
T
Q
D
G
E
S
G
G
Site 79
S579
F
P
E
Q
A
E
L
S
G
P
E
G
M
D
E
Site 80
T590
G
M
D
E
L
I
S
T
P
S
V
E
D
K
S
Site 81
S592
D
E
L
I
S
T
P
S
V
E
D
K
S
E
E
Site 82
S597
T
P
S
V
E
D
K
S
E
E
P
P
G
T
E
Site 83
T603
K
S
E
E
P
P
G
T
E
L
Q
R
D
T
E
Site 84
T609
G
T
E
L
Q
R
D
T
E
A
S
H
L
A
P
Site 85
S612
L
Q
R
D
T
E
A
S
H
L
A
P
N
H
T
Site 86
T619
S
H
L
A
P
N
H
T
T
F
P
K
I
H
S
Site 87
T620
H
L
A
P
N
H
T
T
F
P
K
I
H
S
R
Site 88
Y632
H
S
R
R
F
R
D
Y
C
S
Q
M
L
S
K
Site 89
S634
R
R
F
R
D
Y
C
S
Q
M
L
S
K
E
V
Site 90
Y660
V
R
F
Q
D
R
M
Y
Q
K
D
P
V
K
A
Site 91
T669
K
D
P
V
K
A
K
T
K
R
R
L
V
L
G
Site 92
T710
S
K
G
G
L
D
D
T
L
H
T
I
I
D
Y
Site 93
Y717
T
L
H
T
I
I
D
Y
A
C
E
Q
N
I
P
Site 94
Y773
T
V
A
A
R
Q
A
Y
K
T
M
L
E
N
V
Site 95
T775
A
A
R
Q
A
Y
K
T
M
L
E
N
V
Q
Q
Site 96
S795
P
R
P
Q
A
P
P
S
L
P
T
Q
G
P
S
Site 97
T798
Q
A
P
P
S
L
P
T
Q
G
P
S
C
P
A
Site 98
S802
S
L
P
T
Q
G
P
S
C
P
A
E
D
G
P
Site 99
Y820
K
E
K
E
E
P
H
Y
I
E
I
W
K
K
H
Site 100
T835
L
E
A
Y
S
G
C
T
L
E
L
E
E
S
L
Site 101
S841
C
T
L
E
L
E
E
S
L
E
A
S
T
S
Q
Site 102
S845
L
E
E
S
L
E
A
S
T
S
Q
M
M
N
L
Site 103
S847
E
S
L
E
A
S
T
S
Q
M
M
N
L
N
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation