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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RSF1
Full Name:
Remodeling and spacing factor 1
Alias:
HBV pX associated protein 8 large isoform; HBXAP; Hepatitis B virus X-associated protein; P325; Rsf-1; XAP8; XAP8alpha
Type:
Transcription, coactivator/corepressor
Mass (Da):
163821
Number AA:
1441
UniProt ID:
Q96T23
International Prot ID:
IPI00290652
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031213
Uniprot
OncoNet
Molecular Function:
GO:0042393
GO:0016563
GO:0016564
PhosphoSite+
KinaseNET
Biological Process:
GO:0006338
GO:0043392
GO:0045892
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S81
L
M
R
K
I
G
K
S
V
T
A
D
R
W
E
Site 2
T83
R
K
I
G
K
S
V
T
A
D
R
W
E
K
Y
Site 3
Y90
T
A
D
R
W
E
K
Y
L
I
K
I
C
Q
E
Site 4
Y111
W
E
M
E
K
K
G
Y
L
E
M
S
V
E
C
Site 5
S115
K
K
G
Y
L
E
M
S
V
E
C
K
L
A
L
Site 6
T148
I
N
E
E
D
A
D
T
M
R
L
Q
P
I
G
Site 7
Y163
R
D
K
D
G
L
M
Y
W
Y
Q
L
D
Q
D
Site 8
Y165
K
D
G
L
M
Y
W
Y
Q
L
D
Q
D
H
N
Site 9
Y176
Q
D
H
N
V
R
M
Y
I
E
E
Q
D
D
Q
Site 10
T201
N
R
N
E
L
A
E
T
L
A
L
L
K
A
Q
Site 11
S217
D
P
V
L
L
K
N
S
S
Q
Q
D
N
S
S
Site 12
S218
P
V
L
L
K
N
S
S
Q
Q
D
N
S
S
R
Site 13
S223
N
S
S
Q
Q
D
N
S
S
R
E
S
P
S
L
Site 14
S224
S
S
Q
Q
D
N
S
S
R
E
S
P
S
L
E
Site 15
S227
Q
D
N
S
S
R
E
S
P
S
L
E
D
E
E
Site 16
S229
N
S
S
R
E
S
P
S
L
E
D
E
E
T
K
Site 17
T235
P
S
L
E
D
E
E
T
K
K
E
E
E
T
P
Site 18
T241
E
T
K
K
E
E
E
T
P
K
Q
E
E
Q
K
Site 19
S250
K
Q
E
E
Q
K
E
S
E
K
M
K
S
E
E
Site 20
S255
K
E
S
E
K
M
K
S
E
E
Q
P
M
D
L
Site 21
T267
M
D
L
E
N
R
S
T
A
N
V
L
E
E
T
Site 22
S312
K
K
I
I
K
E
E
S
D
S
F
K
E
N
V
Site 23
S314
I
I
K
E
E
S
D
S
F
K
E
N
V
K
P
Site 24
S338
A
D
P
K
D
T
K
S
S
M
E
K
P
V
A
Site 25
S359
E
F
G
G
N
I
K
S
S
H
E
I
T
E
K
Site 26
S360
F
G
G
N
I
K
S
S
H
E
I
T
E
K
S
Site 27
T364
I
K
S
S
H
E
I
T
E
K
S
T
E
E
T
Site 28
S367
S
H
E
I
T
E
K
S
T
E
E
T
E
K
L
Site 29
S392
K
K
R
E
I
K
L
S
D
D
F
D
S
P
V
Site 30
S397
K
L
S
D
D
F
D
S
P
V
K
G
P
L
C
Site 31
S406
V
K
G
P
L
C
K
S
V
T
P
T
K
E
F
Site 32
T408
G
P
L
C
K
S
V
T
P
T
K
E
F
L
K
Site 33
T410
L
C
K
S
V
T
P
T
K
E
F
L
K
D
E
Site 34
S429
E
E
T
C
K
R
I
S
T
I
T
A
L
G
H
Site 35
T430
E
T
C
K
R
I
S
T
I
T
A
L
G
H
E
Site 36
T432
C
K
R
I
S
T
I
T
A
L
G
H
E
G
K
Site 37
S447
Q
L
V
N
G
E
V
S
D
E
R
V
A
P
N
Site 38
T457
R
V
A
P
N
F
K
T
E
P
I
E
T
K
F
Site 39
Y465
E
P
I
E
T
K
F
Y
E
T
K
E
E
S
Y
Site 40
S471
F
Y
E
T
K
E
E
S
Y
S
P
S
K
D
R
Site 41
S473
E
T
K
E
E
S
Y
S
P
S
K
D
R
N
I
Site 42
S475
K
E
E
S
Y
S
P
S
K
D
R
N
I
I
T
Site 43
S489
T
E
G
N
G
T
E
S
L
N
S
V
I
T
S
Site 44
S492
N
G
T
E
S
L
N
S
V
I
T
S
M
K
T
Site 45
S496
S
L
N
S
V
I
T
S
M
K
T
G
E
L
E
Site 46
T506
T
G
E
L
E
K
E
T
A
P
L
R
K
D
A
Site 47
S515
P
L
R
K
D
A
D
S
S
I
S
V
L
E
I
Site 48
S516
L
R
K
D
A
D
S
S
I
S
V
L
E
I
H
Site 49
S518
K
D
A
D
S
S
I
S
V
L
E
I
H
S
Q
Site 50
S524
I
S
V
L
E
I
H
S
Q
K
A
Q
I
E
E
Site 51
T539
P
D
P
P
E
M
E
T
S
L
D
S
S
E
M
Site 52
S540
D
P
P
E
M
E
T
S
L
D
S
S
E
M
A
Site 53
S544
M
E
T
S
L
D
S
S
E
M
A
K
D
L
S
Site 54
S551
S
E
M
A
K
D
L
S
S
K
T
A
L
S
S
Site 55
S552
E
M
A
K
D
L
S
S
K
T
A
L
S
S
T
Site 56
T554
A
K
D
L
S
S
K
T
A
L
S
S
T
E
S
Site 57
S557
L
S
S
K
T
A
L
S
S
T
E
S
C
T
M
Site 58
S558
S
S
K
T
A
L
S
S
T
E
S
C
T
M
K
Site 59
T559
S
K
T
A
L
S
S
T
E
S
C
T
M
K
G
Site 60
S561
T
A
L
S
S
T
E
S
C
T
M
K
G
E
E
Site 61
S570
T
M
K
G
E
E
K
S
P
K
T
K
K
D
K
Site 62
S591
C
L
E
K
L
E
K
S
K
K
T
F
L
D
K
Site 63
T594
K
L
E
K
S
K
K
T
F
L
D
K
D
A
Q
Site 64
S604
D
K
D
A
Q
R
L
S
P
I
P
E
E
V
P
Site 65
S613
I
P
E
E
V
P
K
S
T
L
E
S
E
K
P
Site 66
T614
P
E
E
V
P
K
S
T
L
E
S
E
K
P
G
Site 67
S617
V
P
K
S
T
L
E
S
E
K
P
G
S
P
E
Site 68
S622
L
E
S
E
K
P
G
S
P
E
A
A
E
T
S
Site 69
T628
G
S
P
E
A
A
E
T
S
P
P
S
N
I
I
Site 70
S629
S
P
E
A
A
E
T
S
P
P
S
N
I
I
D
Site 71
S632
A
A
E
T
S
P
P
S
N
I
I
D
H
C
E
Site 72
S643
D
H
C
E
K
L
A
S
E
K
E
V
V
E
C
Site 73
S652
K
E
V
V
E
C
Q
S
T
S
T
V
G
G
Q
Site 74
T653
E
V
V
E
C
Q
S
T
S
T
V
G
G
Q
S
Site 75
T655
V
E
C
Q
S
T
S
T
V
G
G
Q
S
V
K
Site 76
T668
V
K
K
V
D
L
E
T
L
K
E
D
S
E
F
Site 77
S689
N
L
D
N
A
Q
T
S
G
I
E
E
P
S
E
Site 78
S695
T
S
G
I
E
E
P
S
E
T
K
G
S
M
Q
Site 79
T697
G
I
E
E
P
S
E
T
K
G
S
M
Q
K
S
Site 80
S700
E
P
S
E
T
K
G
S
M
Q
K
S
K
F
K
Site 81
S704
T
K
G
S
M
Q
K
S
K
F
K
Y
K
L
V
Site 82
Y708
M
Q
K
S
K
F
K
Y
K
L
V
P
E
E
E
Site 83
T717
L
V
P
E
E
E
T
T
A
S
E
N
T
E
I
Site 84
S719
P
E
E
E
T
T
A
S
E
N
T
E
I
T
S
Site 85
S726
S
E
N
T
E
I
T
S
E
R
Q
K
E
G
I
Site 86
T736
Q
K
E
G
I
K
L
T
I
R
I
S
S
R
K
Site 87
S740
I
K
L
T
I
R
I
S
S
R
K
K
K
P
D
Site 88
S741
K
L
T
I
R
I
S
S
R
K
K
K
P
D
S
Site 89
S748
S
R
K
K
K
P
D
S
P
P
K
V
L
E
P
Site 90
T769
T
E
K
E
E
E
K
T
N
V
G
R
T
L
R
Site 91
T774
E
K
T
N
V
G
R
T
L
R
R
S
P
R
I
Site 92
S778
V
G
R
T
L
R
R
S
P
R
I
S
R
P
T
Site 93
S782
L
R
R
S
P
R
I
S
R
P
T
A
K
V
A
Site 94
T785
S
P
R
I
S
R
P
T
A
K
V
A
E
I
R
Site 95
S826
K
K
E
I
L
K
K
S
E
K
D
T
N
S
K
Site 96
T830
L
K
K
S
E
K
D
T
N
S
K
V
S
K
V
Site 97
S832
K
S
E
K
D
T
N
S
K
V
S
K
V
K
P
Site 98
T846
P
K
G
K
V
R
W
T
G
S
R
T
R
G
R
Site 99
S848
G
K
V
R
W
T
G
S
R
T
R
G
R
W
K
Site 100
Y856
R
T
R
G
R
W
K
Y
S
S
N
D
E
S
E
Site 101
S857
T
R
G
R
W
K
Y
S
S
N
D
E
S
E
G
Site 102
S858
R
G
R
W
K
Y
S
S
N
D
E
S
E
G
S
Site 103
S862
K
Y
S
S
N
D
E
S
E
G
S
G
S
E
K
Site 104
S865
S
N
D
E
S
E
G
S
G
S
E
K
S
S
A
Site 105
S867
D
E
S
E
G
S
G
S
E
K
S
S
A
A
S
Site 106
S870
E
G
S
G
S
E
K
S
S
A
A
S
E
E
E
Site 107
S871
G
S
G
S
E
K
S
S
A
A
S
E
E
E
E
Site 108
S874
S
E
K
S
S
A
A
S
E
E
E
E
E
K
E
Site 109
S882
E
E
E
E
E
K
E
S
E
E
A
I
L
A
D
Site 110
Y916
C
D
S
C
D
S
G
Y
H
T
A
C
L
R
P
Site 111
T918
S
C
D
S
G
Y
H
T
A
C
L
R
P
P
L
Site 112
Y973
R
R
K
E
R
L
V
Y
V
G
I
S
I
E
N
Site 113
S990
P
P
Q
E
P
D
F
S
E
D
Q
E
E
K
K
Site 114
S1003
K
K
K
D
S
K
K
S
K
A
N
L
L
E
R
Site 115
S1012
A
N
L
L
E
R
R
S
T
R
T
R
K
C
I
Site 116
T1013
N
L
L
E
R
R
S
T
R
T
R
K
C
I
S
Site 117
T1015
L
E
R
R
S
T
R
T
R
K
C
I
S
Y
R
Site 118
S1020
T
R
T
R
K
C
I
S
Y
R
F
D
E
F
D
Site 119
Y1021
R
T
R
K
C
I
S
Y
R
F
D
E
F
D
E
Site 120
S1053
V
G
R
G
K
D
I
S
T
I
T
G
H
R
G
Site 121
T1054
G
R
G
K
D
I
S
T
I
T
G
H
R
G
K
Site 122
T1056
G
K
D
I
S
T
I
T
G
H
R
G
K
D
I
Site 123
S1064
G
H
R
G
K
D
I
S
T
I
L
D
E
E
R
Site 124
S1096
R
R
L
N
D
L
D
S
D
S
N
L
D
E
E
Site 125
S1098
L
N
D
L
D
S
D
S
N
L
D
E
E
E
S
Site 126
S1105
S
N
L
D
E
E
E
S
E
D
E
F
K
I
S
Site 127
S1112
S
E
D
E
F
K
I
S
D
G
S
Q
D
E
F
Site 128
S1115
E
F
K
I
S
D
G
S
Q
D
E
F
V
V
S
Site 129
S1122
S
Q
D
E
F
V
V
S
D
E
N
P
D
E
S
Site 130
S1129
S
D
E
N
P
D
E
S
E
E
D
P
P
S
N
Site 131
S1135
E
S
E
E
D
P
P
S
N
D
D
S
D
T
D
Site 132
S1139
D
P
P
S
N
D
D
S
D
T
D
F
C
S
R
Site 133
T1141
P
S
N
D
D
S
D
T
D
F
C
S
R
R
L
Site 134
S1145
D
S
D
T
D
F
C
S
R
R
L
R
R
H
P
Site 135
S1153
R
R
L
R
R
H
P
S
R
P
M
R
Q
S
R
Site 136
S1159
P
S
R
P
M
R
Q
S
R
R
L
R
R
K
T
Site 137
T1166
S
R
R
L
R
R
K
T
P
K
K
K
Y
S
D
Site 138
S1172
K
T
P
K
K
K
Y
S
D
D
D
E
E
E
E
Site 139
S1180
D
D
D
E
E
E
E
S
E
E
N
S
R
D
S
Site 140
S1184
E
E
E
S
E
E
N
S
R
D
S
E
S
D
F
Site 141
S1187
S
E
E
N
S
R
D
S
E
S
D
F
S
D
D
Site 142
S1189
E
N
S
R
D
S
E
S
D
F
S
D
D
F
S
Site 143
S1192
R
D
S
E
S
D
F
S
D
D
F
S
D
D
F
Site 144
S1196
S
D
F
S
D
D
F
S
D
D
F
V
E
T
R
Site 145
T1202
F
S
D
D
F
V
E
T
R
R
R
R
S
R
R
Site 146
S1207
V
E
T
R
R
R
R
S
R
R
N
Q
K
R
Q
Site 147
Y1217
N
Q
K
R
Q
I
N
Y
K
E
D
S
E
S
D
Site 148
S1221
Q
I
N
Y
K
E
D
S
E
S
D
G
S
Q
K
Site 149
S1223
N
Y
K
E
D
S
E
S
D
G
S
Q
K
S
L
Site 150
S1226
E
D
S
E
S
D
G
S
Q
K
S
L
R
R
G
Site 151
S1229
E
S
D
G
S
Q
K
S
L
R
R
G
K
E
I
Site 152
S1245
R
V
H
K
R
R
L
S
S
S
E
S
E
E
S
Site 153
S1246
V
H
K
R
R
L
S
S
S
E
S
E
E
S
Y
Site 154
S1247
H
K
R
R
L
S
S
S
E
S
E
E
S
Y
L
Site 155
S1249
R
R
L
S
S
S
E
S
E
E
S
Y
L
S
K
Site 156
S1252
S
S
S
E
S
E
E
S
Y
L
S
K
N
S
E
Site 157
Y1253
S
S
E
S
E
E
S
Y
L
S
K
N
S
E
D
Site 158
S1255
E
S
E
E
S
Y
L
S
K
N
S
E
D
D
E
Site 159
S1258
E
S
Y
L
S
K
N
S
E
D
D
E
L
A
K
Site 160
S1267
D
D
E
L
A
K
E
S
K
R
S
V
R
K
R
Site 161
S1270
L
A
K
E
S
K
R
S
V
R
K
R
G
R
S
Site 162
S1277
S
V
R
K
R
G
R
S
T
D
E
Y
S
E
A
Site 163
T1278
V
R
K
R
G
R
S
T
D
E
Y
S
E
A
D
Site 164
Y1281
R
G
R
S
T
D
E
Y
S
E
A
D
E
E
E
Site 165
S1282
G
R
S
T
D
E
Y
S
E
A
D
E
E
E
E
Site 166
S1296
E
E
E
E
G
K
P
S
R
K
R
L
H
R
I
Site 167
T1305
K
R
L
H
R
I
E
T
D
E
E
E
S
C
D
Site 168
S1310
I
E
T
D
E
E
E
S
C
D
N
A
H
G
D
Site 169
S1325
A
N
Q
P
A
R
D
S
Q
P
R
V
L
P
S
Site 170
S1332
S
Q
P
R
V
L
P
S
E
Q
E
S
T
K
K
Site 171
S1336
V
L
P
S
E
Q
E
S
T
K
K
P
Y
R
I
Site 172
T1337
L
P
S
E
Q
E
S
T
K
K
P
Y
R
I
E
Site 173
Y1341
Q
E
S
T
K
K
P
Y
R
I
E
S
D
E
E
Site 174
S1345
K
K
P
Y
R
I
E
S
D
E
E
E
D
F
E
Site 175
S1359
E
N
V
G
K
V
G
S
P
L
D
Y
S
L
V
Site 176
Y1363
K
V
G
S
P
L
D
Y
S
L
V
D
L
P
S
Site 177
S1364
V
G
S
P
L
D
Y
S
L
V
D
L
P
S
T
Site 178
S1370
Y
S
L
V
D
L
P
S
T
N
G
Q
S
P
G
Site 179
T1371
S
L
V
D
L
P
S
T
N
G
Q
S
P
G
K
Site 180
S1375
L
P
S
T
N
G
Q
S
P
G
K
A
I
E
N
Site 181
S1391
I
G
K
P
T
E
K
S
Q
T
P
K
D
N
S
Site 182
T1393
K
P
T
E
K
S
Q
T
P
K
D
N
S
T
A
Site 183
S1398
S
Q
T
P
K
D
N
S
T
A
S
A
S
L
A
Site 184
T1399
Q
T
P
K
D
N
S
T
A
S
A
S
L
A
S
Site 185
S1401
P
K
D
N
S
T
A
S
A
S
L
A
S
N
G
Site 186
S1403
D
N
S
T
A
S
A
S
L
A
S
N
G
T
S
Site 187
S1406
T
A
S
A
S
L
A
S
N
G
T
S
G
G
Q
Site 188
S1410
S
L
A
S
N
G
T
S
G
G
Q
E
A
G
A
Site 189
Y1434
R
V
T
D
L
V
D
Y
V
C
N
S
E
Q
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation