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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZIC5
Full Name:
Zinc finger protein ZIC 5
Alias:
zic family member 5 (odd-paired homolog, Drosophila); Zic family member 5 (odd-paired)
Type:
Mass (Da):
65850
Number AA:
639
UniProt ID:
Q96T25
International Prot ID:
IPI00163395
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0002009
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
E
P
P
L
S
K
R
N
P
P
A
L
Site 2
T65
A
D
P
G
V
A
T
T
P
L
G
P
E
H
M
Site 3
S76
P
E
H
M
A
Q
A
S
T
L
G
L
S
P
P
Site 4
T77
E
H
M
A
Q
A
S
T
L
G
L
S
P
P
S
Site 5
S81
Q
A
S
T
L
G
L
S
P
P
S
Q
A
F
P
Site 6
S84
T
L
G
L
S
P
P
S
Q
A
F
P
A
H
P
Site 7
S111
V
A
H
P
G
A
G
S
Y
P
C
G
G
G
S
Site 8
Y112
A
H
P
G
A
G
S
Y
P
C
G
G
G
S
S
Site 9
S118
S
Y
P
C
G
G
G
S
S
G
A
Q
P
S
A
Site 10
S119
Y
P
C
G
G
G
S
S
G
A
Q
P
S
A
P
Site 11
S124
G
S
S
G
A
Q
P
S
A
P
P
P
P
A
P
Site 12
T136
P
A
P
P
L
P
P
T
P
S
P
P
P
P
P
Site 13
S138
P
P
L
P
P
T
P
S
P
P
P
P
P
P
P
Site 14
S152
P
P
P
P
P
A
L
S
G
Y
T
T
T
N
S
Site 15
Y154
P
P
P
A
L
S
G
Y
T
T
T
N
S
G
G
Site 16
T156
P
A
L
S
G
Y
T
T
T
N
S
G
G
G
G
Site 17
S159
S
G
Y
T
T
T
N
S
G
G
G
G
S
S
G
Site 18
S165
N
S
G
G
G
G
S
S
G
K
G
H
S
R
D
Site 19
S170
G
S
S
G
K
G
H
S
R
D
F
V
L
R
R
Site 20
T182
L
R
R
D
L
S
A
T
A
P
A
A
A
M
H
Site 21
S199
P
L
G
G
E
Q
R
S
G
T
G
S
P
Q
H
Site 22
T201
G
G
E
Q
R
S
G
T
G
S
P
Q
H
P
A
Site 23
S203
E
Q
R
S
G
T
G
S
P
Q
H
P
A
P
P
Site 24
S213
H
P
A
P
P
P
H
S
A
G
M
F
I
S
A
Site 25
T223
M
F
I
S
A
S
G
T
Y
A
G
P
D
G
S
Site 26
Y224
F
I
S
A
S
G
T
Y
A
G
P
D
G
S
G
Site 27
S230
T
Y
A
G
P
D
G
S
G
G
P
A
L
F
P
Site 28
T242
L
F
P
A
L
H
D
T
P
G
A
P
G
G
H
Site 29
S284
E
P
P
F
A
P
R
S
G
D
A
H
Y
G
A
Site 30
Y289
P
R
S
G
D
A
H
Y
G
A
V
A
A
A
A
Site 31
Y363
A
A
G
A
F
L
R
Y
M
R
Q
P
I
K
Q
Site 32
S408
A
G
G
A
K
P
C
S
K
T
F
G
T
M
H
Site 33
T410
G
A
K
P
C
S
K
T
F
G
T
M
H
E
L
Site 34
T422
H
E
L
V
N
H
V
T
V
E
H
V
G
G
P
Site 35
Y452
G
K
P
F
K
A
K
Y
K
L
I
N
H
I
R
Site 36
T462
I
N
H
I
R
V
H
T
G
E
K
P
F
P
C
Site 37
S481
C
G
K
V
F
A
R
S
E
N
L
K
I
H
K
Site 38
T492
K
I
H
K
R
T
H
T
G
E
K
P
F
K
C
Site 39
S511
C
D
R
K
F
A
N
S
S
D
R
K
K
H
S
Site 40
S512
D
R
K
F
A
N
S
S
D
R
K
K
H
S
H
Site 41
S518
S
S
D
R
K
K
H
S
H
V
H
T
S
D
K
Site 42
T522
K
K
H
S
H
V
H
T
S
D
K
P
Y
Y
C
Site 43
Y527
V
H
T
S
D
K
P
Y
Y
C
K
I
R
G
C
Site 44
Y528
H
T
S
D
K
P
Y
Y
C
K
I
R
G
C
D
Site 45
S537
K
I
R
G
C
D
K
S
Y
T
H
P
S
S
L
Site 46
Y538
I
R
G
C
D
K
S
Y
T
H
P
S
S
L
R
Site 47
T539
R
G
C
D
K
S
Y
T
H
P
S
S
L
R
K
Site 48
S542
D
K
S
Y
T
H
P
S
S
L
R
K
H
M
K
Site 49
S543
K
S
Y
T
H
P
S
S
L
R
K
H
M
K
I
Site 50
S554
H
M
K
I
H
C
K
S
P
P
P
S
P
G
P
Site 51
S558
H
C
K
S
P
P
P
S
P
G
P
L
G
Y
S
Site 52
Y564
P
S
P
G
P
L
G
Y
S
S
V
G
T
P
V
Site 53
S565
S
P
G
P
L
G
Y
S
S
V
G
T
P
V
G
Site 54
S576
T
P
V
G
A
P
L
S
P
V
L
D
P
A
R
Site 55
S584
P
V
L
D
P
A
R
S
H
S
S
T
L
S
P
Site 56
S586
L
D
P
A
R
S
H
S
S
T
L
S
P
Q
V
Site 57
T588
P
A
R
S
H
S
S
T
L
S
P
Q
V
T
N
Site 58
S590
R
S
H
S
S
T
L
S
P
Q
V
T
N
L
N
Site 59
T594
S
T
L
S
P
Q
V
T
N
L
N
E
W
Y
V
Site 60
Y600
V
T
N
L
N
E
W
Y
V
C
Q
A
S
G
A
Site 61
S609
C
Q
A
S
G
A
P
S
H
L
H
T
P
S
S
Site 62
T613
G
A
P
S
H
L
H
T
P
S
S
N
G
T
T
Site 63
S615
P
S
H
L
H
T
P
S
S
N
G
T
T
S
E
Site 64
S616
S
H
L
H
T
P
S
S
N
G
T
T
S
E
T
Site 65
S621
P
S
S
N
G
T
T
S
E
T
E
D
E
E
I
Site 66
Y629
E
T
E
D
E
E
I
Y
G
N
P
E
V
V
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation