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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
INSM2
Full Name:
Insulinoma-associated protein 2
Alias:
Zinc finger protein IA-6
Type:
Mass (Da):
59491
Number AA:
566
UniProt ID:
Q96T92
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
R
G
F
L
V
K
R
T
K
R
T
G
G
L
Y
Site 2
Y17
T
K
R
T
G
G
L
Y
R
V
R
L
A
E
R
Site 3
S43
P
F
L
E
E
A
P
S
A
S
L
P
G
A
E
Site 4
S45
L
E
E
A
P
S
A
S
L
P
G
A
E
R
A
Site 5
T53
L
P
G
A
E
R
A
T
P
P
T
R
E
E
P
Site 6
T56
A
E
R
A
T
P
P
T
R
E
E
P
G
K
G
Site 7
S73
A
E
A
A
R
E
Q
S
G
S
P
C
R
A
A
Site 8
S75
A
A
R
E
Q
S
G
S
P
C
R
A
A
G
V
Site 9
S83
P
C
R
A
A
G
V
S
P
G
T
G
G
R
E
Site 10
S105
G
R
E
G
P
G
P
S
P
S
P
S
P
S
P
Site 11
S107
E
G
P
G
P
S
P
S
P
S
P
S
P
A
K
Site 12
S109
P
G
P
S
P
S
P
S
P
S
P
A
K
P
A
Site 13
S111
P
S
P
S
P
S
P
S
P
A
K
P
A
G
A
Site 14
S134
R
C
L
S
S
P
V
S
A
E
S
F
P
G
G
Site 15
S137
S
S
P
V
S
A
E
S
F
P
G
G
A
A
A
Site 16
S185
Q
P
D
P
A
P
L
S
A
A
L
Q
S
L
K
Site 17
T205
E
R
R
G
K
A
P
T
G
C
A
S
G
P
A
Site 18
S226
P
K
A
M
R
K
L
S
F
A
D
E
V
T
T
Site 19
S250
E
E
E
P
G
A
P
S
R
G
L
G
G
S
R
Site 20
S256
P
S
R
G
L
G
G
S
R
T
P
L
G
E
F
Site 21
T258
R
G
L
G
G
S
R
T
P
L
G
E
F
I
C
Site 22
Y272
C
Q
L
C
K
E
Q
Y
A
D
P
F
A
L
A
Site 23
S284
A
L
A
Q
H
R
C
S
R
I
V
R
V
E
Y
Site 24
Y291
S
R
I
V
R
V
E
Y
R
C
P
E
C
D
K
Site 25
T324
P
A
A
A
N
A
A
T
V
S
S
A
D
G
K
Site 26
S327
A
N
A
A
T
V
S
S
A
D
G
K
P
P
S
Site 27
S334
S
A
D
G
K
P
P
S
S
S
S
S
S
S
R
Site 28
S335
A
D
G
K
P
P
S
S
S
S
S
S
S
R
D
Site 29
S336
D
G
K
P
P
S
S
S
S
S
S
S
R
D
S
Site 30
S337
G
K
P
P
S
S
S
S
S
S
S
R
D
S
G
Site 31
S338
K
P
P
S
S
S
S
S
S
S
R
D
S
G
A
Site 32
S339
P
P
S
S
S
S
S
S
S
R
D
S
G
A
I
Site 33
S340
P
S
S
S
S
S
S
S
R
D
S
G
A
I
A
Site 34
S343
S
S
S
S
S
R
D
S
G
A
I
A
S
F
L
Site 35
S348
R
D
S
G
A
I
A
S
F
L
A
E
G
K
E
Site 36
S372
Q
H
P
Q
A
R
D
S
S
G
A
D
Q
H
P
Site 37
S373
H
P
Q
A
R
D
S
S
G
A
D
Q
H
P
D
Site 38
S381
G
A
D
Q
H
P
D
S
A
P
R
Q
G
L
Q
Site 39
T391
R
Q
G
L
Q
V
L
T
H
P
E
P
P
L
P
Site 40
Y402
P
P
L
P
Q
G
P
Y
T
E
G
V
L
G
R
Site 41
T403
P
L
P
Q
G
P
Y
T
E
G
V
L
G
R
R
Site 42
S416
R
R
V
P
V
P
G
S
T
S
G
G
R
G
S
Site 43
S418
V
P
V
P
G
S
T
S
G
G
R
G
S
E
I
Site 44
S423
S
T
S
G
G
R
G
S
E
I
F
V
C
P
Y
Site 45
Y430
S
E
I
F
V
C
P
Y
C
H
K
K
F
R
R
Site 46
Y440
K
K
F
R
R
Q
A
Y
L
R
K
H
L
S
T
Site 47
S446
A
Y
L
R
K
H
L
S
T
H
E
A
G
S
A
Site 48
T447
Y
L
R
K
H
L
S
T
H
E
A
G
S
A
R
Site 49
S452
L
S
T
H
E
A
G
S
A
R
A
L
A
P
G
Site 50
T510
L
A
G
A
P
P
E
T
S
G
P
S
G
P
S
Site 51
S511
A
G
A
P
P
E
T
S
G
P
S
G
P
S
D
Site 52
S514
P
P
E
T
S
G
P
S
G
P
S
D
G
S
A
Site 53
S520
P
S
G
P
S
D
G
S
A
Q
Q
I
F
S
C
Site 54
S532
F
S
C
K
H
C
P
S
T
F
F
S
S
P
G
Site 55
T533
S
C
K
H
C
P
S
T
F
F
S
S
P
G
L
Site 56
S536
H
C
P
S
T
F
F
S
S
P
G
L
T
R
H
Site 57
S537
C
P
S
T
F
F
S
S
P
G
L
T
R
H
I
Site 58
S550
H
I
N
K
C
H
P
S
E
S
R
Q
V
L
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation