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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBCB
Full Name:
Tubulin-folding cofactor B
Alias:
CG22; CKAP1; CKAPI; Cytoskeleton-associated protein CKAPI; Tubulin folding cofactor B; Tubulin-specific chaperone B
Type:
Chaperone; Cytoskeletal protein
Mass (Da):
27326
Number AA:
244
UniProt ID:
Q99426
International Prot ID:
IPI00293126
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
F
I
S
S
S
L
N
T
F
R
S
E
K
R
Y
Site 2
S24
S
S
L
N
T
F
R
S
E
K
R
Y
S
R
S
Site 3
Y28
T
F
R
S
E
K
R
Y
S
R
S
L
T
I
A
Site 4
S29
F
R
S
E
K
R
Y
S
R
S
L
T
I
A
E
Site 5
S31
S
E
K
R
Y
S
R
S
L
T
I
A
E
F
K
Site 6
T33
K
R
Y
S
R
S
L
T
I
A
E
F
K
C
K
Site 7
Y57
S
C
M
E
L
E
L
Y
G
V
D
D
K
F
Y
Site 8
Y64
Y
G
V
D
D
K
F
Y
S
K
L
D
Q
E
D
Site 9
S65
G
V
D
D
K
F
Y
S
K
L
D
Q
E
D
A
Site 10
S76
Q
E
D
A
L
L
G
S
Y
P
V
D
D
G
C
Site 11
Y77
E
D
A
L
L
G
S
Y
P
V
D
D
G
C
R
Site 12
S91
R
I
H
V
I
D
H
S
G
A
R
L
G
E
Y
Site 13
Y98
S
G
A
R
L
G
E
Y
E
D
V
S
R
V
E
Site 14
S102
L
G
E
Y
E
D
V
S
R
V
E
K
Y
T
I
Site 15
Y107
D
V
S
R
V
E
K
Y
T
I
S
Q
E
A
Y
Site 16
T108
V
S
R
V
E
K
Y
T
I
S
Q
E
A
Y
D
Site 17
S110
R
V
E
K
Y
T
I
S
Q
E
A
Y
D
Q
R
Site 18
Y114
Y
T
I
S
Q
E
A
Y
D
Q
R
Q
D
T
V
Site 19
T120
A
Y
D
Q
R
Q
D
T
V
R
S
F
L
K
R
Site 20
S123
Q
R
Q
D
T
V
R
S
F
L
K
R
S
K
L
Site 21
S128
V
R
S
F
L
K
R
S
K
L
G
R
Y
N
E
Site 22
Y133
K
R
S
K
L
G
R
Y
N
E
E
E
R
A
Q
Site 23
S158
E
E
K
A
Q
A
S
S
I
P
V
G
S
R
C
Site 24
S173
E
V
R
A
A
G
Q
S
P
R
R
G
T
V
M
Site 25
T178
G
Q
S
P
R
R
G
T
V
M
Y
V
G
L
T
Site 26
Y181
P
R
R
G
T
V
M
Y
V
G
L
T
D
F
K
Site 27
Y191
L
T
D
F
K
P
G
Y
W
I
G
V
R
Y
D
Site 28
Y197
G
Y
W
I
G
V
R
Y
D
E
P
L
G
K
N
Site 29
S207
P
L
G
K
N
D
G
S
V
N
G
K
R
Y
F
Site 30
Y213
G
S
V
N
G
K
R
Y
F
E
C
Q
A
K
Y
Site 31
Y239
G
D
F
P
E
E
D
Y
G
L
D
E
I
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation