KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NELL2
Full Name:
Protein kinase C-binding protein NELL2
Alias:
NEL-like protein 2;Nel-related protein 2
Type:
Mass (Da):
91346
Number AA:
816
UniProt ID:
Q99435
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S41
T
E
L
E
L
G
E
S
T
T
G
V
R
Q
V
Site 2
T63
K
A
F
L
F
Q
D
T
P
R
S
I
K
A
S
Site 3
S66
L
F
Q
D
T
P
R
S
I
K
A
S
T
A
T
Site 4
S70
T
P
R
S
I
K
A
S
T
A
T
A
E
Q
F
Site 5
S105
L
N
S
G
V
I
L
S
I
H
H
L
D
H
R
Site 6
Y113
I
H
H
L
D
H
R
Y
L
E
L
E
S
S
G
Site 7
S119
R
Y
L
E
L
E
S
S
G
H
R
N
E
V
R
Site 8
Y129
R
N
E
V
R
L
H
Y
R
S
G
S
H
R
P
Site 9
S131
E
V
R
L
H
Y
R
S
G
S
H
R
P
H
T
Site 10
S133
R
L
H
Y
R
S
G
S
H
R
P
H
T
E
V
Site 11
T138
S
G
S
H
R
P
H
T
E
V
F
P
Y
I
L
Site 12
Y143
P
H
T
E
V
F
P
Y
I
L
A
D
D
K
W
Site 13
S154
D
D
K
W
H
K
L
S
L
A
I
S
A
S
H
Site 14
Y172
H
I
D
C
N
K
I
Y
E
R
V
V
E
K
P
Site 15
T181
R
V
V
E
K
P
S
T
D
L
P
L
G
T
T
Site 16
T188
T
D
L
P
L
G
T
T
F
W
L
G
Q
R
N
Site 17
Y200
Q
R
N
N
A
H
G
Y
F
K
G
I
M
Q
D
Site 18
T251
L
Q
D
I
L
A
K
T
S
A
K
L
S
R
A
Site 19
S252
Q
D
I
L
A
K
T
S
A
K
L
S
R
A
E
Site 20
S256
A
K
T
S
A
K
L
S
R
A
E
Q
R
M
N
Site 21
Y281
C
T
M
K
G
T
T
Y
R
E
F
E
S
W
I
Site 22
S317
N
P
D
C
P
L
K
S
A
L
A
Y
V
D
G
Site 23
Y321
P
L
K
S
A
L
A
Y
V
D
G
K
C
C
K
Site 24
Y341
C
Q
F
Q
G
R
T
Y
F
E
G
E
R
N
T
Site 25
T348
Y
F
E
G
E
R
N
T
V
Y
S
S
S
G
V
Site 26
Y350
E
G
E
R
N
T
V
Y
S
S
S
G
V
C
V
Site 27
S351
G
E
R
N
T
V
Y
S
S
S
G
V
C
V
L
Site 28
S353
R
N
T
V
Y
S
S
S
G
V
C
V
L
Y
E
Site 29
Y359
S
S
G
V
C
V
L
Y
E
C
K
D
Q
T
M
Site 30
T365
L
Y
E
C
K
D
Q
T
M
K
L
V
E
S
S
Site 31
S382
P
A
L
D
C
P
E
S
H
Q
I
T
L
S
H
Site 32
S423
L
N
D
R
A
V
C
S
C
R
D
G
F
R
A
Site 33
Y437
A
L
R
E
D
N
A
Y
C
E
D
I
D
E
C
Site 34
Y472
M
C
I
C
K
T
G
Y
I
R
I
D
D
Y
S
Site 35
Y478
G
Y
I
R
I
D
D
Y
S
C
T
E
H
D
E
Site 36
S594
Y
H
D
N
G
M
F
S
P
S
G
E
S
C
E
Site 37
T608
E
D
I
D
E
C
G
T
G
R
H
S
C
A
N
Site 38
Y626
C
F
N
L
D
G
G
Y
D
C
R
C
P
H
G
Site 39
S697
P
E
C
D
P
R
L
S
S
Q
C
L
H
Q
N
Site 40
S698
E
C
D
P
R
L
S
S
Q
C
L
H
Q
N
G
Site 41
Y709
H
Q
N
G
E
T
L
Y
N
S
G
D
T
W
V
Site 42
S744
P
D
V
E
C
E
F
S
I
L
P
E
N
E
C
Site 43
T764
T
D
P
C
Q
A
D
T
I
R
N
D
I
T
K
Site 44
T770
D
T
I
R
N
D
I
T
K
T
C
L
D
E
M
Site 45
T772
I
R
N
D
I
T
K
T
C
L
D
E
M
N
V
Site 46
T783
E
M
N
V
V
R
F
T
G
S
S
W
I
K
H
Site 47
S786
V
V
R
F
T
G
S
S
W
I
K
H
G
T
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation