PhosphoNET

           
Protein Info 
   
Short Name:  PHOX2B
Full Name:  Paired mesoderm homeobox protein 2B
Alias:  Neuroblastoma Phox;PHOX2B homeodomain protein;Paired-like homeobox 2B
Type: 
Mass (Da):  31621
Number AA:  314
UniProt ID:  Q99453
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y8MYKMEYSYLNSSAYE
Site 2S12EYSYLNSSAYESCMA
Site 3Y14SYLNSSAYESCMAGM
Site 4S16LNSSAYESCMAGMDT
Site 5S28MDTSSLASAYADFSS
Site 6Y30TSSLASAYADFSSCS
Site 7S34ASAYADFSSCSQASG
Site 8S35SAYADFSSCSQASGF
Site 9S37YADFSSCSQASGFQY
Site 10Y44SQASGFQYNPIRTTF
Site 11T50QYNPIRTTFGATSGC
Site 12S55RTTFGATSGCPSLTP
Site 13S59GATSGCPSLTPGSCS
Site 14T61TSGCPSLTPGSCSLG
Site 15S66SLTPGSCSLGTLRDH
Site 16T69PGSCSLGTLRDHQSS
Site 17S75GTLRDHQSSPYAAVP
Site 18S76TLRDHQSSPYAAVPY
Site 19Y78RDHQSSPYAAVPYKL
Site 20T87AVPYKLFTDHGGLNE
Site 21T103RKQRRIRTTFTSAQL
Site 22T104KQRRIRTTFTSAQLK
Site 23S107RIRTTFTSAQLKELE
Site 24T120LERVFAETHYPDIYT
Site 25Y122RVFAETHYPDIYTRE
Site 26Y126ETHYPDIYTREELAL
Site 27S171AAAAKNGSSGKKSDS
Site 28S172AAAKNGSSGKKSDSS
Site 29S176NGSSGKKSDSSRDDE
Site 30S178SSGKKSDSSRDDESK
Site 31S179SGKKSDSSRDDESKE
Site 32S184DSSRDDESKEAKSTD
Site 33S189DESKEAKSTDPDSTG
Site 34T190ESKEAKSTDPDSTGG
Site 35S194AKSTDPDSTGGPGPN
Site 36T195KSTDPDSTGGPGPNP
Site 37T205PGPNPNPTPSCGANG
Site 38S207PNPNPTPSCGANGGG
Site 39S219GGGGGGPSPAGAPGA
Site 40T281APGPGPITSIPDSLG
Site 41S282PGPGPITSIPDSLGG
Site 42S297PFASVLSSLQRPNGA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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