PhosphoNET

           
Protein Info 
   
Short Name:  STAC
Full Name:  SH3 and cysteine-rich domain-containing protein
Alias:  Src homology 3 and cysteine-rich domain-containing protein
Type: 
Mass (Da):  44554
Number AA:  402
UniProt ID:  Q99469
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MIPPSSPREDGVD
Site 2S27VGAEQPPSPASTSSQ
Site 3S30EQPPSPASTSSQESK
Site 4T31QPPSPASTSSQESKL
Site 5S32PPSPASTSSQESKLQ
Site 6S33PSPASTSSQESKLQK
Site 7S36ASTSSQESKLQKLKR
Site 8S44KLQKLKRSLSFKTKS
Site 9S46QKLKRSLSFKTKSLR
Site 10T49KRSLSFKTKSLRSKS
Site 11S51SLSFKTKSLRSKSAD
Site 12S56TKSLRSKSADNFFQR
Site 13S66NFFQRTNSEDMKLQA
Site 14S80AHMVAEISPSSSPLP
Site 15S84AEISPSSSPLPAPGS
Site 16S91SPLPAPGSLTSTPAR
Site 17T93LPAPGSLTSTPARAG
Site 18S94PAPGSLTSTPARAGL
Site 19T95APGSLTSTPARAGLH
Site 20Y113KAHAFQEYIFKKPTF
Site 21Y170LPKGFRRYYSSPLLI
Site 22Y171PKGFRRYYSSPLLIH
Site 23S172KGFRRYYSSPLLIHE
Site 24S173GFRRYYSSPLLIHEQ
Site 25Y200GNKVDPVYETLRFGT
Site 26T202KVDPVYETLRFGTSL
Site 27T207YETLRFGTSLAQRTK
Site 28S208ETLRFGTSLAQRTKK
Site 29T213GTSLAQRTKKGSSGS
Site 30S217AQRTKKGSSGSGSDS
Site 31S218QRTKKGSSGSGSDSP
Site 32S220TKKGSSGSGSDSPHR
Site 33S222KGSSGSGSDSPHRTS
Site 34S224SSGSGSDSPHRTSTS
Site 35T228GSDSPHRTSTSDLVE
Site 36S229SDSPHRTSTSDLVEV
Site 37T230DSPHRTSTSDLVEVP
Site 38S231SPHRTSTSDLVEVPE
Site 39S253GYDLRKRSNSVFTYP
Site 40S255DLRKRSNSVFTYPEN
Site 41Y259RSNSVFTYPENGTDD
Site 42S279KNINHQGSLSKDPLQ
Site 43S281INHQGSLSKDPLQMN
Site 44T313MRPGDIITLLEDSNE
Site 45S375ENQICVSSEEEQDGF
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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