PhosphoNET

           
Protein Info 
   
Short Name:  S1PR3
Full Name:  Sphingosine 1-phosphate receptor 3
Alias:  Edg3; Edg-3; Endothelial differentiation sphingolipid G protein-coupled receptor 3; Endothelial differentiation, sphingolipid G protein-coupled receptor, 3; Flj37523; Flj93220; Lpb3; Lysosphingolipid receptor; Mgc71696; S1p3; S1pr3; Sphingosine-1-phosphate receptor 3
Type: 
Mass (Da):  42250
Number AA:  378
UniProt ID:  Q99500
International Prot ID:  IPI00015983
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005887     Uniprot OncoNet
Molecular Function:  GO:0008289  GO:0001619   PhosphoSite+ KinaseNET
Biological Process:  GO:0009653  GO:0007204  GO:0006954 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y22NETLREHYQYVGKLA
Site 2Y24TLREHYQYVGKLAGR
Site 3S36AGRLKEASEGSTLTT
Site 4Y75NKFHNRMYFFIGNLA
Site 5S105MSGKKTFSLSPTVWF
Site 6S107GKKTFSLSPTVWFLR
Site 7T109KTFSLSPTVWFLREG
Site 8T139IAIERHLTMIKMRPY
Site 9Y146TMIKMRPYDANKRHR
Site 10T187HNLPDCSTILPLYSK
Site 11S224RIYFLVKSSSRKVAN
Site 12S225IYFLVKSSSRKVANH
Site 13S226YFLVKSSSRKVANHN
Site 14S235KVANHNNSERSMALL
Site 15T299AMNPVIYTLASKEMR
Site 16S326RGRGARASPIQPALD
Site 17S335IQPALDPSRSKSSSS
Site 18S337PALDPSRSKSSSSNN
Site 19S339LDPSRSKSSSSNNSS
Site 20S340DPSRSKSSSSNNSSH
Site 21S341PSRSKSSSSNNSSHS
Site 22S342SRSKSSSSNNSSHSP
Site 23S345KSSSSNNSSHSPKVK
Site 24S346SSSSNNSSHSPKVKE
Site 25S348SSNNSSHSPKVKEDL
Site 26T358VKEDLPHTAPSSCIM
Site 27S362LPHTAPSSCIMDKNA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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