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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GAS2L1
Full Name:
GAS2-like protein 1
Alias:
GAR22; GAS2-related protein on chromosome 22; growth arrest-specific 2 like 1; growth arrest-specific protein 2-like 1
Type:
Cytoskeletal protein
Mass (Da):
72717
Number AA:
681
UniProt ID:
Q99501
International Prot ID:
IPI00306170
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007050
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
I
A
G
S
A
A
K
S
V
R
P
F
R
S
S
Site 2
S22
S
V
R
P
F
R
S
S
E
A
Y
V
E
A
M
Site 3
Y25
P
F
R
S
S
E
A
Y
V
E
A
M
K
E
D
Site 4
T193
E
T
A
P
A
P
G
T
P
A
R
G
P
R
M
Site 5
T201
P
A
R
G
P
R
M
T
P
S
D
L
R
N
L
Site 6
S203
R
G
P
R
M
T
P
S
D
L
R
N
L
D
E
Site 7
Y235
I
K
V
S
E
G
K
Y
R
V
G
D
S
S
L
Site 8
T263
R
V
G
G
G
W
D
T
L
E
H
Y
L
D
K
Site 9
Y267
G
W
D
T
L
E
H
Y
L
D
K
H
D
P
C
Site 10
S277
K
H
D
P
C
R
C
S
S
T
A
H
R
P
P
Site 11
S278
H
D
P
C
R
C
S
S
T
A
H
R
P
P
Q
Site 12
T290
P
P
Q
P
R
V
C
T
F
S
P
Q
R
V
S
Site 13
S292
Q
P
R
V
C
T
F
S
P
Q
R
V
S
P
T
Site 14
S297
T
F
S
P
Q
R
V
S
P
T
T
S
P
R
P
Site 15
T299
S
P
Q
R
V
S
P
T
T
S
P
R
P
A
S
Site 16
T300
P
Q
R
V
S
P
T
T
S
P
R
P
A
S
P
Site 17
S301
Q
R
V
S
P
T
T
S
P
R
P
A
S
P
V
Site 18
S306
T
T
S
P
R
P
A
S
P
V
P
G
S
E
R
Site 19
S311
P
A
S
P
V
P
G
S
E
R
R
G
S
R
P
Site 20
S316
P
G
S
E
R
R
G
S
R
P
E
M
T
P
V
Site 21
T321
R
G
S
R
P
E
M
T
P
V
S
L
R
S
T
Site 22
S324
R
P
E
M
T
P
V
S
L
R
S
T
K
E
G
Site 23
T328
T
P
V
S
L
R
S
T
K
E
G
P
E
T
P
Site 24
T334
S
T
K
E
G
P
E
T
P
P
R
P
R
D
Q
Site 25
S348
Q
L
P
P
H
P
R
S
R
R
Y
S
G
D
S
Site 26
Y351
P
H
P
R
S
R
R
Y
S
G
D
S
D
S
S
Site 27
S352
H
P
R
S
R
R
Y
S
G
D
S
D
S
S
A
Site 28
S355
S
R
R
Y
S
G
D
S
D
S
S
A
S
S
A
Site 29
S357
R
Y
S
G
D
S
D
S
S
A
S
S
A
Q
S
Site 30
S358
Y
S
G
D
S
D
S
S
A
S
S
A
Q
S
G
Site 31
S360
G
D
S
D
S
S
A
S
S
A
Q
S
G
P
L
Site 32
S361
D
S
D
S
S
A
S
S
A
Q
S
G
P
L
G
Site 33
S364
S
S
A
S
S
A
Q
S
G
P
L
G
T
R
S
Site 34
S371
S
G
P
L
G
T
R
S
D
D
T
G
T
G
P
Site 35
T374
L
G
T
R
S
D
D
T
G
T
G
P
R
R
E
Site 36
T376
T
R
S
D
D
T
G
T
G
P
R
R
E
R
P
Site 37
S384
G
P
R
R
E
R
P
S
R
R
L
T
T
G
T
Site 38
T388
E
R
P
S
R
R
L
T
T
G
T
P
A
S
P
Site 39
T389
R
P
S
R
R
L
T
T
G
T
P
A
S
P
R
Site 40
T391
S
R
R
L
T
T
G
T
P
A
S
P
R
R
P
Site 41
S394
L
T
T
G
T
P
A
S
P
R
R
P
P
A
L
Site 42
S403
R
R
P
P
A
L
R
S
Q
S
R
D
R
L
D
Site 43
S405
P
P
A
L
R
S
Q
S
R
D
R
L
D
R
G
Site 44
S426
G
G
R
G
A
Q
L
S
V
P
S
P
A
R
R
Site 45
S429
G
A
Q
L
S
V
P
S
P
A
R
R
A
R
S
Site 46
S436
S
P
A
R
R
A
R
S
Q
S
R
E
E
Q
A
Site 47
S438
A
R
R
A
R
S
Q
S
R
E
E
Q
A
V
L
Site 48
S456
R
D
R
D
G
Q
H
S
W
V
P
R
G
R
G
Site 49
S464
W
V
P
R
G
R
G
S
G
G
S
G
R
S
T
Site 50
S467
R
G
R
G
S
G
G
S
G
R
S
T
P
Q
T
Site 51
S470
G
S
G
G
S
G
R
S
T
P
Q
T
P
R
A
Site 52
T471
S
G
G
S
G
R
S
T
P
Q
T
P
R
A
R
Site 53
T474
S
G
R
S
T
P
Q
T
P
R
A
R
S
P
A
Site 54
S479
P
Q
T
P
R
A
R
S
P
A
A
P
R
L
S
Site 55
S486
S
P
A
A
P
R
L
S
R
V
S
S
P
S
P
Site 56
S489
A
P
R
L
S
R
V
S
S
P
S
P
E
L
G
Site 57
S490
P
R
L
S
R
V
S
S
P
S
P
E
L
G
T
Site 58
S492
L
S
R
V
S
S
P
S
P
E
L
G
T
T
P
Site 59
T497
S
P
S
P
E
L
G
T
T
P
A
S
I
F
R
Site 60
T498
P
S
P
E
L
G
T
T
P
A
S
I
F
R
T
Site 61
S501
E
L
G
T
T
P
A
S
I
F
R
T
P
L
Q
Site 62
T505
T
P
A
S
I
F
R
T
P
L
Q
L
D
P
Q
Site 63
S558
P
D
P
P
A
P
D
S
A
Y
C
S
S
S
S
Site 64
Y560
P
P
A
P
D
S
A
Y
C
S
S
S
S
S
S
Site 65
S562
A
P
D
S
A
Y
C
S
S
S
S
S
S
S
S
Site 66
S563
P
D
S
A
Y
C
S
S
S
S
S
S
S
S
L
Site 67
S564
D
S
A
Y
C
S
S
S
S
S
S
S
S
L
S
Site 68
S565
S
A
Y
C
S
S
S
S
S
S
S
S
L
S
V
Site 69
S566
A
Y
C
S
S
S
S
S
S
S
S
L
S
V
L
Site 70
S567
Y
C
S
S
S
S
S
S
S
S
L
S
V
L
G
Site 71
S568
C
S
S
S
S
S
S
S
S
L
S
V
L
G
G
Site 72
S569
S
S
S
S
S
S
S
S
L
S
V
L
G
G
K
Site 73
S571
S
S
S
S
S
S
L
S
V
L
G
G
K
C
G
Site 74
S583
K
C
G
Q
P
G
D
S
G
R
T
A
N
G
L
Site 75
T586
Q
P
G
D
S
G
R
T
A
N
G
L
P
G
P
Site 76
S595
N
G
L
P
G
P
R
S
Q
A
L
S
S
S
S
Site 77
S599
G
P
R
S
Q
A
L
S
S
S
S
D
E
G
S
Site 78
S600
P
R
S
Q
A
L
S
S
S
S
D
E
G
S
P
Site 79
S601
R
S
Q
A
L
S
S
S
S
D
E
G
S
P
C
Site 80
S602
S
Q
A
L
S
S
S
S
D
E
G
S
P
C
P
Site 81
S606
S
S
S
S
D
E
G
S
P
C
P
G
M
G
G
Site 82
S620
G
P
L
D
A
P
G
S
P
L
A
C
T
E
P
Site 83
T625
P
G
S
P
L
A
C
T
E
P
S
R
T
W
A
Site 84
T630
A
C
T
E
P
S
R
T
W
A
R
G
R
M
D
Site 85
T638
W
A
R
G
R
M
D
T
Q
P
D
R
K
P
S
Site 86
S645
T
Q
P
D
R
K
P
S
R
I
P
T
P
R
G
Site 87
T649
R
K
P
S
R
I
P
T
P
R
G
P
R
R
P
Site 88
S657
P
R
G
P
R
R
P
S
G
P
A
E
L
G
T
Site 89
T664
S
G
P
A
E
L
G
T
W
H
A
L
H
S
V
Site 90
S670
G
T
W
H
A
L
H
S
V
T
P
R
A
E
P
Site 91
T672
W
H
A
L
H
S
V
T
P
R
A
E
P
D
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation