PhosphoNET

           
Protein Info 
   
Short Name:  EYA1
Full Name:  Eyes absent homolog 1
Alias: 
Type: 
Mass (Da):  64593
Number AA:  592
UniProt ID:  Q99502
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T7_MEMQDLTSPHSRLS
Site 2S8MEMQDLTSPHSRLSG
Site 3S11QDLTSPHSRLSGSSE
Site 4S14TSPHSRLSGSSESPS
Site 5S16PHSRLSGSSESPSGP
Site 6S17HSRLSGSSESPSGPK
Site 7S19RLSGSSESPSGPKLG
Site 8S21SGSSESPSGPKLGNS
Site 9S28SGPKLGNSHINSNSM
Site 10S32LGNSHINSNSMTPNG
Site 11S34NSHINSNSMTPNGTE
Site 12T36HINSNSMTPNGTEVK
Site 13T44PNGTEVKTEPMSSSE
Site 14S48EVKTEPMSSSETAST
Site 15S49VKTEPMSSSETASTT
Site 16S50KTEPMSSSETASTTA
Site 17T52EPMSSSETASTTADG
Site 18S54MSSSETASTTADGSL
Site 19T55SSSETASTTADGSLN
Site 20T56SSETASTTADGSLNN
Site 21S60ASTTADGSLNNFSGS
Site 22S65DGSLNNFSGSAIGSS
Site 23S67SLNNFSGSAIGSSSF
Site 24S71FSGSAIGSSSFSPRP
Site 25S72SGSAIGSSSFSPRPT
Site 26S73GSAIGSSSFSPRPTH
Site 27S75AIGSSSFSPRPTHQF
Site 28T79SSFSPRPTHQFSPPQ
Site 29S83PRPTHQFSPPQIYPS
Site 30Y88QFSPPQIYPSNRPYP
Site 31S90SPPQIYPSNRPYPHI
Site 32Y94IYPSNRPYPHILPTP
Site 33T100PYPHILPTPSSQTMA
Site 34S102PHILPTPSSQTMAAY
Site 35S103HILPTPSSQTMAAYG
Site 36Y127QATAYATYPQPGQPY
Site 37Y134YPQPGQPYGISSYGA
Site 38S137PGQPYGISSYGALWA
Site 39S138GQPYGISSYGALWAG
Site 40T148ALWAGIKTEGGLSQS
Site 41S153IKTEGGLSQSQSPGQ
Site 42S155TEGGLSQSQSPGQTG
Site 43S157GGLSQSQSPGQTGFL
Site 44T161QSQSPGQTGFLSYGT
Site 45S165PGQTGFLSYGTSFST
Site 46S169GFLSYGTSFSTPQPG
Site 47S171LSYGTSFSTPQPGQA
Site 48T172SYGTSFSTPQPGQAP
Site 49S181QPGQAPYSYQMQGSS
Site 50Y182PGQAPYSYQMQGSSF
Site 51S187YSYQMQGSSFTTSSG
Site 52S188SYQMQGSSFTTSSGI
Site 53T191MQGSSFTTSSGIYTG
Site 54S192QGSSFTTSSGIYTGN
Site 55S193GSSFTTSSGIYTGNN
Site 56Y196FTTSSGIYTGNNSLT
Site 57T197TTSSGIYTGNNSLTN
Site 58S201GIYTGNNSLTNSSGF
Site 59T203YTGNNSLTNSSGFNS
Site 60S205GNNSLTNSSGFNSSQ
Site 61S206NNSLTNSSGFNSSQQ
Site 62S210TNSSGFNSSQQDYPS
Site 63S211NSSGFNSSQQDYPSY
Site 64Y215FNSSQQDYPSYPSFG
Site 65S217SSQQDYPSYPSFGQG
Site 66Y218SQQDYPSYPSFGQGQ
Site 67S220QDYPSYPSFGQGQYA
Site 68Y229GQGQYAQYYNSSPYP
Site 69Y230QGQYAQYYNSSPYPA
Site 70Y235QYYNSSPYPAHYMTS
Site 71Y239SSPYPAHYMTSSNTS
Site 72T241PYPAHYMTSSNTSPT
Site 73S242YPAHYMTSSNTSPTT
Site 74S243PAHYMTSSNTSPTTP
Site 75S246YMTSSNTSPTTPSTN
Site 76T249SSNTSPTTPSTNATY
Site 77T255TTPSTNATYQLQEPP
Site 78S263YQLQEPPSGITSQAV
Site 79S267EPPSGITSQAVTDPT
Site 80T271GITSQAVTDPTAEYS
Site 81T274SQAVTDPTAEYSTIH
Site 82S278TDPTAEYSTIHSPST
Site 83S282AEYSTIHSPSTPIKD
Site 84S284YSTIHSPSTPIKDSD
Site 85T285STIHSPSTPIKDSDS
Site 86S290PSTPIKDSDSDRLRR
Site 87S292TPIKDSDSDRLRRGS
Site 88S299SDRLRRGSDGKSRGR
Site 89S303RRGSDGKSRGRGRRN
Site 90S314GRRNNNPSPPPDSDL
Site 91S319NPSPPPDSDLERVFI
Site 92S343FHSLLTGSYANRYGR
Site 93Y344HSLLTGSYANRYGRD
Site 94Y348TGSYANRYGRDPPTS
Site 95T354RYGRDPPTSVSLGLR
Site 96S355YGRDPPTSVSLGLRM
Site 97S357RDPPTSVSLGLRMEE
Site 98S391QVHIDDVSSDDNGQD
Site 99S392VHIDDVSSDDNGQDL
Site 100S400DDNGQDLSTYNFGTD
Site 101T401DNGQDLSTYNFGTDG
Site 102Y402NGQDLSTYNFGTDGF
Site 103Y438MRKLAFRYRRVKEIY
Site 104Y445YRRVKEIYNTYKNNV
Site 105T447RVKEIYNTYKNNVGG
Site 106Y448VKEIYNTYKNNVGGL
Site 107S528FPIENIYSATKIGKE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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