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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FMO2
Full Name:
Dimethylaniline monooxygenase [N-oxide-forming] 2
Alias:
Dimethylaniline oxidase 2;FMO 1B1;Pulmonary flavin-containing monooxygenase 2
Type:
Mass (Da):
60907
Number AA:
535
UniProt ID:
Q99518
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
A
V
I
G
A
G
V
S
G
L
I
S
L
K
C
Site 2
S17
A
G
V
S
G
L
I
S
L
K
C
C
V
D
E
Site 3
S53
N
V
E
D
G
R
A
S
I
Y
Q
S
V
V
T
Site 4
Y55
E
D
G
R
A
S
I
Y
Q
S
V
V
T
N
T
Site 5
S57
G
R
A
S
I
Y
Q
S
V
V
T
N
T
S
K
Site 6
S63
Q
S
V
V
T
N
T
S
K
E
M
S
C
F
S
Site 7
S70
S
K
E
M
S
C
F
S
D
F
P
M
P
E
D
Site 8
Y90
H
N
S
K
L
L
E
Y
F
R
I
F
A
K
K
Site 9
Y103
K
K
F
D
L
L
K
Y
I
Q
F
Q
T
T
V
Site 10
T108
L
K
Y
I
Q
F
Q
T
T
V
L
S
V
R
K
Site 11
S112
Q
F
Q
T
T
V
L
S
V
R
K
C
P
D
F
Site 12
S120
V
R
K
C
P
D
F
S
S
S
G
Q
W
K
V
Site 13
S121
R
K
C
P
D
F
S
S
S
G
Q
W
K
V
V
Site 14
S122
K
C
P
D
F
S
S
S
G
Q
W
K
V
V
T
Site 15
T129
S
G
Q
W
K
V
V
T
Q
S
N
G
K
E
Q
Site 16
S159
L
P
H
I
P
L
K
S
F
P
G
M
E
R
F
Site 17
Y170
M
E
R
F
K
G
Q
Y
F
H
S
R
Q
Y
K
Site 18
Y176
Q
Y
F
H
S
R
Q
Y
K
H
P
D
G
F
E
Site 19
T218
F
I
S
T
R
H
G
T
W
V
M
S
R
I
S
Site 20
Y229
S
R
I
S
E
D
G
Y
P
W
D
S
V
F
H
Site 21
T237
P
W
D
S
V
F
H
T
R
F
R
S
M
L
R
Site 22
S241
V
F
H
T
R
F
R
S
M
L
R
N
V
L
P
Site 23
Y277
G
L
E
P
Q
N
K
Y
I
M
K
E
P
V
L
Site 24
S301
C
G
A
I
K
V
K
S
T
V
K
E
L
T
E
Site 25
T309
T
V
K
E
L
T
E
T
S
A
I
F
E
D
G
Site 26
T317
S
A
I
F
E
D
G
T
V
E
E
N
I
D
V
Site 27
S341
S
F
P
F
L
E
D
S
L
V
K
V
E
N
N
Site 28
Y353
E
N
N
M
V
S
L
Y
K
Y
I
F
P
A
H
Site 29
T381
P
L
G
S
I
F
P
T
A
E
L
Q
A
R
W
Site 30
S398
R
V
F
K
G
L
C
S
L
P
S
E
R
T
M
Site 31
S401
K
G
L
C
S
L
P
S
E
R
T
M
M
M
D
Site 32
S423
R
I
D
L
F
G
E
S
Q
S
Q
T
L
Q
T
Site 33
S425
D
L
F
G
E
S
Q
S
Q
T
L
Q
T
N
Y
Site 34
T427
F
G
E
S
Q
S
Q
T
L
Q
T
N
Y
V
D
Site 35
Y432
S
Q
T
L
Q
T
N
Y
V
D
Y
L
D
E
L
Site 36
Y435
L
Q
T
N
Y
V
D
Y
L
D
E
L
A
L
E
Site 37
S451
G
A
K
P
D
F
C
S
L
L
F
K
D
P
K
Site 38
Y464
P
K
L
A
V
R
L
Y
F
G
P
C
N
S
Y
Site 39
Y471
Y
F
G
P
C
N
S
Y
Q
Y
R
L
V
G
P
Site 40
Y473
G
P
C
N
S
Y
Q
Y
R
L
V
G
P
G
Q
Site 41
T490
G
A
R
N
A
I
F
T
Q
K
Q
R
I
L
K
Site 42
T501
R
I
L
K
P
L
K
T
R
A
L
K
D
S
S
Site 43
S507
K
T
R
A
L
K
D
S
S
N
F
S
V
S
F
Site 44
S508
T
R
A
L
K
D
S
S
N
F
S
V
S
F
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation