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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SORT1
Full Name:
Sortilin
Alias:
100 kDa NT receptor; Glycoprotein 95; Gp95; Neurotensin receptor 3; NT3; NTR3; SORT; Sortilin; Sortilin 1
Type:
Receptor, miscellaneous
Mass (Da):
92068
Number AA:
831
UniProt ID:
Q99523
International Prot ID:
IPI00217882
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000267
GO:0000323
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0004871
GO:0004872
GO:0004888
PhosphoSite+
KinaseNET
Biological Process:
GO:0001503
GO:0006810
GO:0006886
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
W
G
A
A
D
G
L
S
R
W
P
H
G
L
G
Site 2
T31
L
Q
L
L
P
P
S
T
L
S
Q
D
R
L
D
Site 3
S33
L
L
P
P
S
T
L
S
Q
D
R
L
D
A
P
Site 4
T168
I
N
N
T
F
I
R
T
E
F
G
M
A
I
G
Site 5
T185
N
S
G
K
V
V
L
T
A
E
V
S
G
G
S
Site 6
T298
D
L
G
K
S
F
K
T
I
G
V
K
I
Y
S
Site 7
S305
T
I
G
V
K
I
Y
S
F
G
L
G
G
R
F
Site 8
Y560
E
G
Q
C
W
Q
T
Y
T
F
T
R
D
P
I
Site 9
S756
K
Q
N
S
K
S
N
S
V
P
I
I
L
A
I
Site 10
Y792
G
R
F
L
V
H
R
Y
S
V
L
Q
Q
H
A
Site 11
S793
R
F
L
V
H
R
Y
S
V
L
Q
Q
H
A
E
Site 12
T812
D
G
V
D
A
L
D
T
A
S
H
T
N
K
S
Site 13
S814
V
D
A
L
D
T
A
S
H
T
N
K
S
G
Y
Site 14
S819
T
A
S
H
T
N
K
S
G
Y
H
D
D
S
D
Site 15
Y821
S
H
T
N
K
S
G
Y
H
D
D
S
D
E
D
Site 16
S825
K
S
G
Y
H
D
D
S
D
E
D
L
L
E
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation