PhosphoNET

           
Protein Info 
   
Short Name:  LGMN
Full Name:  Legumain
Alias:  Asparaginyl endopeptidase;Protease, cysteine 1
Type: 
Mass (Da):  49411
Number AA:  433
UniProt ID:  Q99538
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y41VAGSNGWYNYRHQAD
Site 2Y76MMYDDIAYSEDNPTP
Site 3T82AYSEDNPTPGIVINR
Site 4Y96RPNGTDVYQGVPKDY
Site 5Y103YQGVPKDYTGEDVTP
Site 6T104QGVPKDYTGEDVTPQ
Site 7T109DYTGEDVTPQNFLAV
Site 8S135GSGKVLKSGPQDHVF
Site 9Y144PQDHVFIYFTDHGST
Site 10Y172DLNETIHYMYKHKMY
Site 11Y185MYRKMVFYIEACESG
Site 12S215TAANPRESSYACYYD
Site 13S216AANPRESSYACYYDE
Site 14Y217ANPRESSYACYYDEK
Site 15Y220RESSYACYYDEKRST
Site 16Y221ESSYACYYDEKRSTY
Site 17Y228YDEKRSTYLGDWYSV
Site 18Y233STYLGDWYSVNWMED
Site 19S241SVNWMEDSDVEDLTK
Site 20T247DSDVEDLTKETLHKQ
Site 21Y255KETLHKQYHLVKSHT
Site 22T264LVKSHTNTSHVMQYG
Site 23S291QGMKRKASSPVPLPP
Site 24S292GMKRKASSPVPLPPV
Site 25T305PVTHLDLTPSPDVPL
Site 26T313PSPDVPLTIMKRKLM
Site 27T322MKRKLMNTNDLEESR
Site 28T332LEESRQLTEEIQRHL
Site 29S348ARHLIEKSVRKIVSL
Site 30S359IVSLLAASEAEVEQL
Site 31S368AEVEQLLSERAPLTG
Site 32T374LSERAPLTGHSCYPE
Site 33S377RAPLTGHSCYPEALL
Site 34Y398FNWHSPTYEYALRHL
Site 35Y416VNLCEKPYPLHRIKL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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