KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZRF1
Full Name:
DnaJ homolog subfamily C member 2
Alias:
DnaJ (Hsp40), subfamily C, member 2; DnaJ C2; DNJC2; M-phase phosphoprotein 11; MPHOSPH11; MPP11; ZUO1; Zuotin; Zuotin-related factor 1
Type:
Chaperone; DNA replication; Cell cycle regulation
Mass (Da):
71897
Number AA:
621
UniProt ID:
Q99543
International Prot ID:
IPI00455199
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0031072
GO:0051082
PhosphoSite+
KinaseNET
Biological Process:
GO:0006457
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
S
A
A
D
G
R
G
T
A
I
T
H
A
L
T
Site 2
T16
D
G
R
G
T
A
I
T
H
A
L
T
S
A
S
Site 3
S47
K
R
R
N
R
N
A
S
A
S
F
Q
E
L
E
Site 4
S49
R
N
R
N
A
S
A
S
F
Q
E
L
E
D
K
Site 5
S60
L
E
D
K
K
E
L
S
E
E
S
E
D
E
E
Site 6
S63
K
K
E
L
S
E
E
S
E
D
E
E
L
Q
L
Site 7
T78
E
E
F
P
M
L
K
T
L
D
P
K
D
W
K
Site 8
Y90
D
W
K
N
Q
D
H
Y
A
V
L
G
L
G
H
Site 9
Y100
L
G
L
G
H
V
R
Y
K
A
T
Q
R
Q
I
Site 10
Y137
I
K
E
G
D
N
D
Y
F
T
C
I
T
K
A
Site 11
S149
T
K
A
Y
E
M
L
S
D
P
V
K
R
R
A
Site 12
S159
V
K
R
R
A
F
N
S
V
D
P
T
F
D
N
Site 13
T163
A
F
N
S
V
D
P
T
F
D
N
S
V
P
S
Site 14
S167
V
D
P
T
F
D
N
S
V
P
S
K
S
E
A
Site 15
S172
D
N
S
V
P
S
K
S
E
A
K
D
N
F
F
Site 16
T183
D
N
F
F
E
V
F
T
P
V
F
E
R
N
S
Site 17
S190
T
P
V
F
E
R
N
S
R
W
S
N
K
K
N
Site 18
S193
F
E
R
N
S
R
W
S
N
K
K
N
V
P
K
Site 19
S206
P
K
L
G
D
M
N
S
S
F
E
D
V
D
I
Site 20
S207
K
L
G
D
M
N
S
S
F
E
D
V
D
I
F
Site 21
S228
F
D
S
W
R
E
F
S
Y
L
D
E
E
E
K
Site 22
Y229
D
S
W
R
E
F
S
Y
L
D
E
E
E
K
E
Site 23
T268
E
E
M
N
R
I
R
T
L
V
D
N
A
Y
S
Site 24
Y274
R
T
L
V
D
N
A
Y
S
C
D
P
R
I
K
Site 25
S391
C
D
R
L
E
L
A
S
L
Q
C
L
N
E
T
Site 26
T400
Q
C
L
N
E
T
L
T
S
C
T
K
E
V
G
Site 27
S437
E
A
R
M
R
Q
A
S
K
N
T
E
K
S
T
Site 28
S443
A
S
K
N
T
E
K
S
T
G
G
G
G
N
G
Site 29
S451
T
G
G
G
G
N
G
S
K
N
W
S
E
D
D
Site 30
S455
G
N
G
S
K
N
W
S
E
D
D
L
Q
L
L
Site 31
S475
L
F
P
A
G
T
N
S
R
W
E
V
I
A
N
Site 32
Y483
R
W
E
V
I
A
N
Y
M
N
I
H
S
S
S
Site 33
S488
A
N
Y
M
N
I
H
S
S
S
G
V
K
R
T
Site 34
S490
Y
M
N
I
H
S
S
S
G
V
K
R
T
A
K
Site 35
S505
D
V
I
G
K
A
K
S
L
Q
K
L
D
P
H
Site 36
T539
V
P
Q
A
D
N
A
T
P
S
E
R
F
E
G
Site 37
S541
Q
A
D
N
A
T
P
S
E
R
F
E
G
P
Y
Site 38
Y548
S
E
R
F
E
G
P
Y
T
D
F
T
P
W
T
Site 39
T549
E
R
F
E
G
P
Y
T
D
F
T
P
W
T
T
Site 40
T552
E
G
P
Y
T
D
F
T
P
W
T
T
E
E
Q
Site 41
Y569
L
E
Q
A
L
K
T
Y
P
V
N
T
P
E
R
Site 42
T573
L
K
T
Y
P
V
N
T
P
E
R
W
E
K
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation