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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NUP88
Full Name:
Nuclear pore complex protein Nup88
Alias:
88 kDa nuclear pore complex protein; Karyoporin; MGC8530; Nuclear pore complex protein Nup88; Nuclear pore complex protein Nup88: Nucleoporin Nup88: 88 kDa nuclear pore complex protein; Nucleoporin 88kDa; Nucleoporin Nup88
Type:
Nucleoporin
Mass (Da):
83542
Number AA:
741
UniProt ID:
Q99567
International Prot ID:
IPI00001738
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005643
Uniprot
OncoNet
Molecular Function:
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0051028
GO:0015031
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S35
R
E
G
L
K
N
Q
S
P
T
E
A
E
K
P
Site 2
T37
G
L
K
N
Q
S
P
T
E
A
E
K
P
A
S
Site 3
S44
T
E
A
E
K
P
A
S
S
S
L
P
S
S
P
Site 4
S45
E
A
E
K
P
A
S
S
S
L
P
S
S
P
P
Site 5
S46
A
E
K
P
A
S
S
S
L
P
S
S
P
P
P
Site 6
S49
P
A
S
S
S
L
P
S
S
P
P
P
Q
L
L
Site 7
S50
A
S
S
S
L
P
S
S
P
P
P
Q
L
L
T
Site 8
T57
S
P
P
P
Q
L
L
T
R
N
V
V
F
G
L
Site 9
S77
L
W
D
G
E
D
S
S
F
L
V
V
R
L
R
Site 10
S87
V
V
R
L
R
G
P
S
G
G
G
E
E
P
A
Site 11
S96
G
G
E
E
P
A
L
S
Q
Y
Q
R
L
L
C
Site 12
Y98
E
E
P
A
L
S
Q
Y
Q
R
L
L
C
I
N
Site 13
S117
E
I
Y
Q
V
L
L
S
P
T
Q
H
H
V
A
Site 14
S144
P
K
R
W
G
K
N
S
E
F
E
G
G
K
S
Site 15
S151
S
E
F
E
G
G
K
S
T
V
N
C
S
T
T
Site 16
T152
E
F
E
G
G
K
S
T
V
N
C
S
T
T
P
Site 17
S156
G
K
S
T
V
N
C
S
T
T
P
V
A
E
R
Site 18
T158
S
T
V
N
C
S
T
T
P
V
A
E
R
F
F
Site 19
T166
P
V
A
E
R
F
F
T
S
S
T
S
L
T
L
Site 20
S167
V
A
E
R
F
F
T
S
S
T
S
L
T
L
K
Site 21
S168
A
E
R
F
F
T
S
S
T
S
L
T
L
K
H
Site 22
T169
E
R
F
F
T
S
S
T
S
L
T
L
K
H
A
Site 23
S170
R
F
F
T
S
S
T
S
L
T
L
K
H
A
A
Site 24
T172
F
T
S
S
T
S
L
T
L
K
H
A
A
W
Y
Site 25
Y179
T
L
K
H
A
A
W
Y
P
S
E
I
L
D
P
Site 26
Y200
S
D
N
V
I
R
I
Y
S
L
R
E
P
Q
T
Site 27
S201
D
N
V
I
R
I
Y
S
L
R
E
P
Q
T
P
Site 28
T207
Y
S
L
R
E
P
Q
T
P
T
N
V
I
I
L
Site 29
S215
P
T
N
V
I
I
L
S
E
A
E
E
E
S
L
Site 30
S221
L
S
E
A
E
E
E
S
L
V
L
N
K
G
R
Site 31
Y230
V
L
N
K
G
R
A
Y
T
A
S
L
G
E
T
Site 32
T231
L
N
K
G
R
A
Y
T
A
S
L
G
E
T
A
Site 33
S233
K
G
R
A
Y
T
A
S
L
G
E
T
A
V
A
Site 34
T252
P
L
A
A
V
P
K
T
L
F
G
Q
N
G
K
Site 35
T279
E
N
G
E
T
F
L
T
Y
I
S
L
L
H
S
Site 36
Y307
H
P
A
A
E
D
N
Y
G
Y
D
A
C
A
V
Site 37
T348
G
E
E
E
D
D
H
T
S
E
K
S
W
D
S
Site 38
S349
E
E
E
D
D
H
T
S
E
K
S
W
D
S
R
Site 39
S355
T
S
E
K
S
W
D
S
R
I
D
L
I
P
S
Site 40
S379
E
L
A
L
K
L
A
S
G
E
D
D
P
F
D
Site 41
S387
G
E
D
D
P
F
D
S
D
F
S
C
P
V
K
Site 42
S390
D
P
F
D
S
D
F
S
C
P
V
K
L
H
R
Site 43
Y405
D
P
K
C
P
S
R
Y
H
C
T
H
E
A
G
Site 44
T419
G
V
H
S
V
G
L
T
W
I
H
K
L
H
K
Site 45
S430
K
L
H
K
F
L
G
S
D
E
E
D
K
D
S
Site 46
S437
S
D
E
E
D
K
D
S
L
Q
E
L
S
T
E
Site 47
S442
K
D
S
L
Q
E
L
S
T
E
Q
K
C
F
V
Site 48
S496
C
L
I
W
P
L
L
S
T
V
H
P
A
S
P
Site 49
S502
L
S
T
V
H
P
A
S
P
P
L
L
C
T
R
Site 50
S517
E
D
V
E
V
A
E
S
P
L
R
V
L
A
E
Site 51
T525
P
L
R
V
L
A
E
T
P
D
S
F
E
K
H
Site 52
S528
V
L
A
E
T
P
D
S
F
E
K
H
I
R
S
Site 53
S535
S
F
E
K
H
I
R
S
I
L
Q
R
S
V
A
Site 54
S540
I
R
S
I
L
Q
R
S
V
A
N
P
A
F
L
Site 55
T569
L
Q
L
L
S
R
A
T
Q
V
F
R
E
Q
Y
Site 56
Y576
T
Q
V
F
R
E
Q
Y
I
L
K
Q
D
L
A
Site 57
S606
K
K
Q
L
E
D
L
S
Y
C
R
E
E
R
K
Site 58
Y607
K
Q
L
E
D
L
S
Y
C
R
E
E
R
K
S
Site 59
S614
Y
C
R
E
E
R
K
S
L
R
E
M
A
E
R
Site 60
Y626
A
E
R
L
A
D
K
Y
E
E
A
K
E
K
Q
Site 61
S646
R
M
K
K
L
L
H
S
F
H
S
E
L
P
V
Site 62
S649
K
L
L
H
S
F
H
S
E
L
P
V
L
S
D
Site 63
S655
H
S
E
L
P
V
L
S
D
S
E
R
D
M
K
Site 64
S657
E
L
P
V
L
S
D
S
E
R
D
M
K
K
E
Site 65
Y688
Q
V
T
M
K
K
D
Y
Q
Q
Q
K
M
E
K
Site 66
S698
Q
K
M
E
K
V
L
S
L
P
K
P
T
I
I
Site 67
S707
P
K
P
T
I
I
L
S
A
Y
Q
R
K
C
I
Site 68
Y709
P
T
I
I
L
S
A
Y
Q
R
K
C
I
Q
S
Site 69
S716
Y
Q
R
K
C
I
Q
S
I
L
K
E
E
G
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation