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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SERPINI1
Full Name:
Neuroserpin
Alias:
Peptidase inhibitor 12;Serpin I1
Type:
Mass (Da):
46427
Number AA:
410
UniProt ID:
Q99574
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
E
E
A
I
A
D
L
S
V
N
M
Y
N
R
L
Site 2
Y34
A
D
L
S
V
N
M
Y
N
R
L
R
A
T
G
Site 3
T40
M
Y
N
R
L
R
A
T
G
E
D
E
N
I
L
Site 4
S49
E
D
E
N
I
L
F
S
P
L
S
I
A
L
A
Site 5
S67
M
E
L
G
A
Q
G
S
T
Q
K
E
I
R
H
Site 6
S75
T
Q
K
E
I
R
H
S
M
G
Y
D
S
L
K
Site 7
Y78
E
I
R
H
S
M
G
Y
D
S
L
K
N
G
E
Site 8
S80
R
H
S
M
G
Y
D
S
L
K
N
G
E
E
F
Site 9
S88
L
K
N
G
E
E
F
S
F
L
K
E
F
S
N
Site 10
T98
K
E
F
S
N
M
V
T
A
K
E
S
Q
Y
V
Site 11
Y104
V
T
A
K
E
S
Q
Y
V
M
K
I
A
N
S
Site 12
Y131
F
L
Q
M
M
K
K
Y
F
N
A
A
V
N
H
Site 13
S168
N
L
V
K
D
L
V
S
P
R
D
F
D
A
A
Site 14
T199
S
Q
F
R
P
E
N
T
R
T
F
S
F
T
K
Site 15
T201
F
R
P
E
N
T
R
T
F
S
F
T
K
D
D
Site 16
S203
P
E
N
T
R
T
F
S
F
T
K
D
D
E
S
Site 17
T205
N
T
R
T
F
S
F
T
K
D
D
E
S
E
V
Site 18
S210
S
F
T
K
D
D
E
S
E
V
Q
I
P
M
M
Site 19
Y218
E
V
Q
I
P
M
M
Y
Q
Q
G
E
F
Y
Y
Site 20
Y224
M
Y
Q
Q
G
E
F
Y
Y
G
E
F
S
D
G
Site 21
Y225
Y
Q
Q
G
E
F
Y
Y
G
E
F
S
D
G
S
Site 22
S229
E
F
Y
Y
G
E
F
S
D
G
S
N
E
A
G
Site 23
S232
Y
G
E
F
S
D
G
S
N
E
A
G
G
I
Y
Site 24
Y239
S
N
E
A
G
G
I
Y
Q
V
L
E
I
P
Y
Site 25
S252
P
Y
E
G
D
E
I
S
M
M
L
V
L
S
R
Site 26
S282
L
V
E
E
W
A
N
S
V
K
K
Q
K
V
E
Site 27
Y291
K
K
Q
K
V
E
V
Y
L
P
R
F
T
V
E
Site 28
T296
E
V
Y
L
P
R
F
T
V
E
Q
E
I
D
L
Site 29
S326
D
A
N
L
T
G
L
S
D
N
K
E
I
F
L
Site 30
S334
D
N
K
E
I
F
L
S
K
A
I
H
K
S
F
Site 31
S340
L
S
K
A
I
H
K
S
F
L
E
V
N
E
E
Site 32
T387
I
R
N
R
R
T
G
T
I
L
F
M
G
R
V
Site 33
T399
G
R
V
M
H
P
E
T
M
N
T
S
G
H
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation