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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NDN
Full Name:
Necdin
Alias:
HsT16328; NECD; PWCR
Type:
DNA binding protein; Transcription factor
Mass (Da):
36086
Number AA:
321
UniProt ID:
Q99608
International Prot ID:
IPI00001102
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043204
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0008285
GO:0040008
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
S
E
Q
S
K
D
L
S
D
P
N
F
A
A
E
Site 2
S20
F
A
A
E
A
P
N
S
E
V
H
S
S
P
G
Site 3
S24
A
P
N
S
E
V
H
S
S
P
G
V
S
E
G
Site 4
S25
P
N
S
E
V
H
S
S
P
G
V
S
E
G
V
Site 5
S29
V
H
S
S
P
G
V
S
E
G
V
P
P
S
A
Site 6
S35
V
S
E
G
V
P
P
S
A
T
L
A
E
P
Q
Site 7
T37
E
G
V
P
P
S
A
T
L
A
E
P
Q
S
P
Site 8
S43
A
T
L
A
E
P
Q
S
P
P
L
G
P
T
A
Site 9
Y108
K
A
H
E
L
M
W
Y
V
L
V
K
D
Q
K
Site 10
Y132
V
K
D
V
I
G
S
Y
K
K
W
C
R
S
I
Site 11
S138
S
Y
K
K
W
C
R
S
I
L
R
R
T
S
L
Site 12
S182
E
L
D
R
V
A
L
S
N
R
M
P
M
T
G
Site 13
T188
L
S
N
R
M
P
M
T
G
L
L
L
M
I
L
Site 14
S208
K
G
R
G
A
R
E
S
A
V
W
N
V
L
R
Site 15
T227
R
P
W
K
K
H
S
T
F
G
D
V
R
K
L
Site 16
Y247
V
Q
M
N
Y
L
K
Y
Q
R
V
P
Y
V
E
Site 17
Y252
L
K
Y
Q
R
V
P
Y
V
E
P
P
E
Y
E
Site 18
Y258
P
Y
V
E
P
P
E
Y
E
F
F
W
G
S
R
Site 19
S267
F
F
W
G
S
R
A
S
R
E
I
T
K
M
Q
Site 20
T271
S
R
A
S
R
E
I
T
K
M
Q
I
M
E
F
Site 21
S292
K
D
P
Q
A
W
P
S
R
Y
R
E
A
L
E
Site 22
T310
A
L
R
E
A
N
P
T
A
H
Y
P
R
S
S
Site 23
Y313
E
A
N
P
T
A
H
Y
P
R
S
S
V
S
E
Site 24
S316
P
T
A
H
Y
P
R
S
S
V
S
E
D
_
_
Site 25
S317
T
A
H
Y
P
R
S
S
V
S
E
D
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation