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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDCA3
Full Name:
Cell division cycle-associated protein 3
Alias:
cell division cycle associated 3; GRCC8; MGC2577; TOME-1; trigger of mitotic entry 1
Type:
Mass (Da):
28998
Number AA:
268
UniProt ID:
Q99618
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0007067
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
S
A
K
S
V
P
V
T
P
A
R
Site 2
T10
S
A
K
S
V
P
V
T
P
A
R
P
P
P
H
Site 3
S29
A
R
V
A
D
P
R
S
P
S
A
G
I
L
R
Site 4
S31
V
A
D
P
R
S
P
S
A
G
I
L
R
T
P
Site 5
T37
P
S
A
G
I
L
R
T
P
I
Q
V
E
S
S
Site 6
S43
R
T
P
I
Q
V
E
S
S
P
Q
P
G
L
P
Site 7
S44
T
P
I
Q
V
E
S
S
P
Q
P
G
L
P
A
Site 8
S64
G
L
K
H
A
Q
D
S
D
P
R
S
P
T
L
Site 9
S68
A
Q
D
S
D
P
R
S
P
T
L
G
I
A
R
Site 10
T70
D
S
D
P
R
S
P
T
L
G
I
A
R
T
P
Site 11
T76
P
T
L
G
I
A
R
T
P
M
K
T
S
S
G
Site 12
T80
I
A
R
T
P
M
K
T
S
S
G
D
P
P
S
Site 13
S81
A
R
T
P
M
K
T
S
S
G
D
P
P
S
P
Site 14
S82
R
T
P
M
K
T
S
S
G
D
P
P
S
P
L
Site 15
S87
T
S
S
G
D
P
P
S
P
L
V
K
Q
L
S
Site 16
S94
S
P
L
V
K
Q
L
S
E
V
F
E
T
E
D
Site 17
T99
Q
L
S
E
V
F
E
T
E
D
S
K
S
N
L
Site 18
S102
E
V
F
E
T
E
D
S
K
S
N
L
P
P
E
Site 19
S104
F
E
T
E
D
S
K
S
N
L
P
P
E
P
V
Site 20
S120
P
P
E
A
P
L
S
S
E
L
D
L
P
L
G
Site 21
S131
L
P
L
G
T
Q
L
S
V
E
E
Q
M
P
P
Site 22
T159
K
E
E
A
R
Q
P
T
E
T
P
V
A
S
Q
Site 23
T161
E
A
R
Q
P
T
E
T
P
V
A
S
Q
S
S
Site 24
S165
P
T
E
T
P
V
A
S
Q
S
S
D
K
P
S
Site 25
S167
E
T
P
V
A
S
Q
S
S
D
K
P
S
R
D
Site 26
S168
T
P
V
A
S
Q
S
S
D
K
P
S
R
D
P
Site 27
S172
S
Q
S
S
D
K
P
S
R
D
P
E
T
P
R
Site 28
T177
K
P
S
R
D
P
E
T
P
R
S
S
G
S
M
Site 29
S180
R
D
P
E
T
P
R
S
S
G
S
M
R
N
R
Site 30
S181
D
P
E
T
P
R
S
S
G
S
M
R
N
R
W
Site 31
S183
E
T
P
R
S
S
G
S
M
R
N
R
W
K
P
Site 32
S192
R
N
R
W
K
P
N
S
S
K
V
L
G
R
S
Site 33
S193
N
R
W
K
P
N
S
S
K
V
L
G
R
S
P
Site 34
S199
S
S
K
V
L
G
R
S
P
L
T
I
L
Q
D
Site 35
T202
V
L
G
R
S
P
L
T
I
L
Q
D
D
N
S
Site 36
S209
T
I
L
Q
D
D
N
S
P
G
T
L
T
L
R
Site 37
T212
Q
D
D
N
S
P
G
T
L
T
L
R
Q
G
K
Site 38
T214
D
N
S
P
G
T
L
T
L
R
Q
G
K
R
P
Site 39
S222
L
R
Q
G
K
R
P
S
P
L
S
E
N
V
S
Site 40
S225
G
K
R
P
S
P
L
S
E
N
V
S
E
L
K
Site 41
S229
S
P
L
S
E
N
V
S
E
L
K
E
G
A
I
Site 42
T245
G
T
G
R
L
L
K
T
G
G
R
A
W
E
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation