PhosphoNET

           
Protein Info 
   
Short Name:  CDX2
Full Name:  Homeobox protein CDX-2
Alias:  CDX-3;Caudal-type homeobox protein 2
Type:  Transcription protein
Mass (Da):  33510
Number AA:  313
UniProt ID:  Q99626
International Prot ID:  IPI00016928
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0043565  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0009887  GO:0006366   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S12YLLDKDVSMYPSSVR
Site 2Y14LDKDVSMYPSSVRHS
Site 3S16KDVSMYPSSVRHSGG
Site 4S17DVSMYPSSVRHSGGL
Site 5S21YPSSVRHSGGLNLAP
Site 6S33LAPQNFVSPPQYPDY
Site 7Y37NFVSPPQYPDYGGYH
Site 8Y40SPPQYPDYGGYHVAA
Site 9S57AAAANLDSAQSPGPS
Site 10S60ANLDSAQSPGPSWPA
Site 11S64SAQSPGPSWPAAYGA
Site 12Y69GPSWPAAYGAPLRED
Site 13S100AHGLNGGSPAAAMGY
Site 14Y107SPAAAMGYSSPADYH
Site 15S109AAAMGYSSPADYHPH
Site 16Y113GYSSPADYHPHHHPH
Site 17T139CASGLLQTLNPGPPG
Site 18S157TAAAEQLSPGGQRRN
Site 19S179PAQQSLGSQVKTRTK
Site 20T183SLGSQVKTRTKDKYR
Site 21Y189KTRTKDKYRVVYTDH
Site 22Y193KDKYRVVYTDHQRLE
Site 23Y207ELEKEFHYSRYITIR
Site 24T212FHYSRYITIRRKAEL
Site 25T222RKAELAATLGLSERQ
Site 26S226LAATLGLSERQVKIW
Site 27S277PQPGPLRSVPEPLSP
Site 28S283RSVPEPLSPVSSLQA
Site 29S286PEPLSPVSSLQASVS
Site 30S287EPLSPVSSLQASVSG
Site 31T310TGGVLNPTVTQ____
Site 32T312GVLNPTVTQ______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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