PhosphoNET

           
Protein Info 
   
Short Name:  PKMYT1
Full Name:  Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Alias:  EC 2.7.11.1; Myt1 kinase; PMYT1
Type:  Protein-serine/tyrosine kinase, dual-specificity, Other group, WEE family
Mass (Da):  54521
Number AA:  499
UniProt ID:  Q99640
International Prot ID:  IPI00384765
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005794  GO:0005783  GO:0019898 Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0005515  GO:0004674 PhosphoSite+ KinaseNET
Biological Process:  GO:0007067  GO:0006468  GO:0000079 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T17MPMPTEGTPPPLSGT
Site 2S22EGTPPPLSGTPIPVP
Site 3T24TPPPLSGTPIPVPAY
Site 4Y31TPIPVPAYFRHAEPG
Site 5S40RHAEPGFSLKRPRGL
Site 6S48LKRPRGLSRSLPPPP
Site 7S50RPRGLSRSLPPPPPA
Site 8S60PPPPAKGSIPISRLF
Site 9S64AKGSIPISRLFPPRT
Site 10T71SRLFPPRTPGWHQLQ
Site 11S83 QLQPRRVSFRGEASE
Site 12S89VSFRGEASETLQSPG
Site 13T91FRGEASETLQSPGYD
Site 14S94EASETLQSPGYDPSR
Site 15Y97ETLQSPGYDPSRPES
Site 16S100QSPGYDPSRPESFFQ
Site 17S104YDPSRPESFFQQSFQ
Site 18S109PESFFQQSFQRLSRL
Site 19S114QQSFQRLSRLGHGSY
Site 20S120LSRLGHGSYGEVFKV
Site 21Y121SRLGHGSYGEVFKVR
Site 22Y136SKEDGRLYAVKRSMS
Site 23S141RLYAVKRSMSPFRGP
Site 24S143YAVKRSMSPFRGPKD
Site 25S160RKLAEVGSHEKVGQH
Site 26Y184WEEGGILYLQTELCG
Site 27Y213PEAQVWGYLRDTLLA
Site 28Y273VQEGDPRYMAPELLQ
Site 29Y319WQQLRQGYLPPEFTA
Site 30T325GYLPPEFTAGLSSEL
Site 31S402HGLAHPASWLQPLGP
Site 32T412QPLGPPATPPGSPPC
Site 33S416PPATPPGSPPCSLLL
Site 34S425PCSLLLDSSLSSNWD
Site 35S426 CSLLLDSSLSSNWDD
Site 36S428LLLDSSLSSNWDDDS
Site 37S429LLDSSLSSNWDDDSL
Site 38S435SSNWDDDSLGPSLSP
Site 39S439DDDSLGPSLSPEAVL
Site 40S441DSLGPSLSPEAVLAR
Site 41T449PEAVLARTVGSTSTP
Site 42T453LARTVGSTSTPRSRC
Site 43S454ARTVGSTSTPRSRCT
Site 44T455RTVGSTSTPRSRCTP
Site 45S458GSTSTPRSRCTPRDA
Site 46T461STPRSRCTPRDALDL
Site 47S469PRDALDLSDINSEPP
Site 48S473LDLSDINSEPPRGSF
Site 49S479NSEPPRGSFPSFEPR
Site 50S482PPRGSFPSFEPRNLL
Site 51S490FEPRNLLSLFEDTLD
Site 52T495 LLSLFEDTLDPT___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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