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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GFI1
Full Name:
Zinc finger protein Gfi-1
Alias:
Growth factor independent 1 transcription repressor; ZNF163
Type:
Cell development/differentiation, cell cycle and apoptosis regulatory protein
Mass (Da):
45297
Number AA:
422
UniProt ID:
Q99684
International Prot ID:
IPI00017068
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0010843
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0010956
GO:0010553
GO:0010957
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
P
R
S
F
L
V
K
S
K
K
A
H
S
Y
H
Site 2
S14
V
K
S
K
K
A
H
S
Y
H
Q
P
R
S
P
Site 3
Y15
K
S
K
K
A
H
S
Y
H
Q
P
R
S
P
G
Site 4
S20
H
S
Y
H
Q
P
R
S
P
G
P
D
Y
S
L
Site 5
Y25
P
R
S
P
G
P
D
Y
S
L
R
L
E
N
V
Site 6
S26
R
S
P
G
P
D
Y
S
L
R
L
E
N
V
P
Site 7
S36
L
E
N
V
P
A
P
S
R
A
D
S
T
S
N
Site 8
S40
P
A
P
S
R
A
D
S
T
S
N
A
G
G
A
Site 9
T41
A
P
S
R
A
D
S
T
S
N
A
G
G
A
K
Site 10
S42
P
S
R
A
D
S
T
S
N
A
G
G
A
K
A
Site 11
S56
A
E
P
R
D
R
L
S
P
E
S
Q
L
T
E
Site 12
S59
R
D
R
L
S
P
E
S
Q
L
T
E
A
P
D
Site 13
T62
L
S
P
E
S
Q
L
T
E
A
P
D
R
A
S
Site 14
S69
T
E
A
P
D
R
A
S
A
S
P
D
S
C
E
Site 15
S71
A
P
D
R
A
S
A
S
P
D
S
C
E
G
S
Site 16
S74
R
A
S
A
S
P
D
S
C
E
G
S
V
C
E
Site 17
S78
S
P
D
S
C
E
G
S
V
C
E
R
S
S
E
Site 18
S83
E
G
S
V
C
E
R
S
S
E
F
E
D
F
W
Site 19
S84
G
S
V
C
E
R
S
S
E
F
E
D
F
W
R
Site 20
S94
E
D
F
W
R
P
P
S
P
S
A
S
P
A
S
Site 21
S96
F
W
R
P
P
S
P
S
A
S
P
A
S
E
K
Site 22
S98
R
P
P
S
P
S
A
S
P
A
S
E
K
S
M
Site 23
S101
S
P
S
A
S
P
A
S
E
K
S
M
C
P
S
Site 24
S104
A
S
P
A
S
E
K
S
M
C
P
S
L
D
E
Site 25
S108
S
E
K
S
M
C
P
S
L
D
E
A
Q
P
F
Site 26
Y122
F
P
L
P
F
K
P
Y
S
W
S
G
L
A
G
Site 27
S123
P
L
P
F
K
P
Y
S
W
S
G
L
A
G
S
Site 28
S125
P
F
K
P
Y
S
W
S
G
L
A
G
S
D
L
Site 29
S130
S
W
S
G
L
A
G
S
D
L
R
H
L
V
Q
Site 30
S138
D
L
R
H
L
V
Q
S
Y
R
P
C
G
A
L
Site 31
Y168
P
G
H
P
A
A
L
Y
G
P
K
R
A
A
G
Site 32
S254
R
L
L
L
G
G
G
S
Y
K
C
I
K
C
S
Site 33
T266
K
C
S
K
V
F
S
T
P
H
G
L
E
V
H
Site 34
S277
L
E
V
H
V
R
R
S
H
S
G
T
R
P
F
Site 35
S279
V
H
V
R
R
S
H
S
G
T
R
P
F
A
C
Site 36
T281
V
R
R
S
H
S
G
T
R
P
F
A
C
E
M
Site 37
S298
K
T
F
G
H
A
V
S
L
E
Q
H
K
A
V
Site 38
S307
E
Q
H
K
A
V
H
S
Q
E
R
S
F
D
C
Site 39
S320
D
C
K
I
C
G
K
S
F
K
R
S
S
T
L
Site 40
S324
C
G
K
S
F
K
R
S
S
T
L
S
T
H
L
Site 41
S325
G
K
S
F
K
R
S
S
T
L
S
T
H
L
L
Site 42
T326
K
S
F
K
R
S
S
T
L
S
T
H
L
L
I
Site 43
S328
F
K
R
S
S
T
L
S
T
H
L
L
I
H
S
Site 44
T329
K
R
S
S
T
L
S
T
H
L
L
I
H
S
D
Site 45
S335
S
T
H
L
L
I
H
S
D
T
R
P
Y
P
C
Site 46
T337
H
L
L
I
H
S
D
T
R
P
Y
P
C
Q
Y
Site 47
Y340
I
H
S
D
T
R
P
Y
P
C
Q
Y
C
G
K
Site 48
S353
G
K
R
F
H
Q
K
S
D
M
K
K
H
T
F
Site 49
T359
K
S
D
M
K
K
H
T
F
I
H
T
G
E
K
Site 50
S378
Q
V
C
G
K
A
F
S
Q
S
S
N
L
I
T
Site 51
S380
C
G
K
A
F
S
Q
S
S
N
L
I
T
H
S
Site 52
S381
G
K
A
F
S
Q
S
S
N
L
I
T
H
S
R
Site 53
T385
S
Q
S
S
N
L
I
T
H
S
R
K
H
T
G
Site 54
S387
S
S
N
L
I
T
H
S
R
K
H
T
G
F
K
Site 55
T391
I
T
H
S
R
K
H
T
G
F
K
P
F
G
C
Site 56
T417
D
L
R
R
H
R
E
T
Q
H
G
L
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation