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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MGLL
Full Name:
Monoglyceride lipase
Alias:
HU-K5; Lysophospholipase; Lysophospholipase homolog; Lysophospholipase-like; MGL
Type:
Lipid Metabolism - glycerolipid; EC 3.1.1.23; Phospholipase
Mass (Da):
33243
Number AA:
303
UniProt ID:
Q99685
International Prot ID:
IPI00455206
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0047372
GO:0004622
PhosphoSite+
KinaseNET
Biological Process:
GO:0006954
GO:0006629
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
P
E
E
S
S
P
R
R
T
P
Q
S
Site 2
T10
E
E
S
S
P
R
R
T
P
Q
S
I
P
Y
Q
Site 3
S13
S
P
R
R
T
P
Q
S
I
P
Y
Q
D
L
P
Site 4
Y29
L
V
N
A
D
G
Q
Y
L
F
C
R
Y
W
K
Site 5
Y34
G
Q
Y
L
F
C
R
Y
W
K
P
T
G
T
P
Site 6
T38
F
C
R
Y
W
K
P
T
G
T
P
K
A
L
I
Site 7
T40
R
Y
W
K
P
T
G
T
P
K
A
L
I
F
V
Site 8
S48
P
K
A
L
I
F
V
S
H
G
A
G
E
H
S
Site 9
S55
S
H
G
A
G
E
H
S
G
R
Y
E
E
L
A
Site 10
Y58
A
G
E
H
S
G
R
Y
E
E
L
A
R
M
L
Site 11
S91
E
G
E
R
M
V
V
S
D
F
H
V
F
V
R
Site 12
S106
D
V
L
Q
H
V
D
S
M
Q
K
D
Y
P
G
Site 13
Y111
V
D
S
M
Q
K
D
Y
P
G
L
P
V
F
L
Site 14
T158
A
N
P
E
S
A
T
T
F
K
V
L
A
A
K
Site 15
S181
L
S
L
G
P
I
D
S
S
V
L
S
R
N
K
Site 16
S182
S
L
G
P
I
D
S
S
V
L
S
R
N
K
T
Site 17
S185
P
I
D
S
S
V
L
S
R
N
K
T
E
V
D
Site 18
T189
S
V
L
S
R
N
K
T
E
V
D
I
Y
N
S
Site 19
Y194
N
K
T
E
V
D
I
Y
N
S
D
P
L
I
C
Site 20
S196
T
E
V
D
I
Y
N
S
D
P
L
I
C
R
A
Site 21
S237
P
F
L
L
L
Q
G
S
A
D
R
L
C
D
S
Site 22
S244
S
A
D
R
L
C
D
S
K
G
A
Y
L
L
M
Site 23
Y248
L
C
D
S
K
G
A
Y
L
L
M
E
L
A
K
Site 24
S256
L
L
M
E
L
A
K
S
Q
D
K
T
L
K
I
Site 25
T260
L
A
K
S
Q
D
K
T
L
K
I
Y
E
G
A
Site 26
S281
E
L
P
E
V
T
N
S
V
F
H
E
I
N
M
Site 27
T296
W
V
S
Q
R
T
A
T
A
G
T
A
S
P
P
Site 28
S301
T
A
T
A
G
T
A
S
P
P
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation