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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Ctip
Full Name:
DNA endonuclease RBBP8
Alias:
CtBP interacting protein; CTBP-interacting protein; CtIP; RBBP8; RBBP-8; Retinoblastoma binding protein 8; Retinoblastoma-interacting protein and myosin-like; RIM
Type:
Transcription, coactivator/corepressor
Mass (Da):
101942
Number AA:
897
UniProt ID:
Q99708
International Prot ID:
IPI00480111
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006281
GO:0000075
GO:0006357
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
N
I
S
G
S
S
C
G
S
P
N
S
Site 2
S10
I
S
G
S
S
C
G
S
P
N
S
A
D
T
S
Site 3
S13
S
S
C
G
S
P
N
S
A
D
T
S
S
D
F
Site 4
T16
G
S
P
N
S
A
D
T
S
S
D
F
K
D
L
Site 5
S17
S
P
N
S
A
D
T
S
S
D
F
K
D
L
W
Site 6
S18
P
N
S
A
D
T
S
S
D
F
K
D
L
W
T
Site 7
T61
Q
R
L
E
E
F
F
T
K
N
Q
Q
L
R
E
Site 8
T126
E
L
M
N
E
R
N
T
L
Q
E
E
N
K
K
Site 9
S163
E
E
D
V
I
P
D
S
P
I
T
A
F
S
F
Site 10
S171
P
I
T
A
F
S
F
S
G
V
N
R
L
R
R
Site 11
T190
H
V
R
Y
I
E
Q
T
H
T
K
L
E
H
S
Site 12
T192
R
Y
I
E
Q
T
H
T
K
L
E
H
S
V
C
Site 13
S207
A
N
E
M
R
K
V
S
K
S
S
T
H
P
Q
Site 14
S209
E
M
R
K
V
S
K
S
S
T
H
P
Q
H
N
Site 15
T211
R
K
V
S
K
S
S
T
H
P
Q
H
N
P
N
Site 16
T227
N
E
I
L
V
A
D
T
Y
D
Q
S
Q
S
P
Site 17
Y228
E
I
L
V
A
D
T
Y
D
Q
S
Q
S
P
M
Site 18
S231
V
A
D
T
Y
D
Q
S
Q
S
P
M
A
K
A
Site 19
S233
D
T
Y
D
Q
S
Q
S
P
M
A
K
A
H
G
Site 20
S243
A
K
A
H
G
T
S
S
Y
T
P
D
K
S
S
Site 21
Y244
K
A
H
G
T
S
S
Y
T
P
D
K
S
S
F
Site 22
T245
A
H
G
T
S
S
Y
T
P
D
K
S
S
F
N
Site 23
S249
S
S
Y
T
P
D
K
S
S
F
N
L
A
T
V
Site 24
S250
S
Y
T
P
D
K
S
S
F
N
L
A
T
V
V
Site 25
S269
G
L
G
V
Q
E
E
S
E
T
Q
G
P
M
S
Site 26
T271
G
V
Q
E
E
S
E
T
Q
G
P
M
S
P
L
Site 27
S276
S
E
T
Q
G
P
M
S
P
L
G
D
E
L
Y
Site 28
Y283
S
P
L
G
D
E
L
Y
H
C
L
E
G
N
H
Site 29
S298
K
K
Q
P
F
E
E
S
T
R
N
T
E
D
S
Site 30
T302
F
E
E
S
T
R
N
T
E
D
S
L
R
F
S
Site 31
S305
S
T
R
N
T
E
D
S
L
R
F
S
D
S
T
Site 32
S309
T
E
D
S
L
R
F
S
D
S
T
S
K
T
P
Site 33
S311
D
S
L
R
F
S
D
S
T
S
K
T
P
P
Q
Site 34
T312
S
L
R
F
S
D
S
T
S
K
T
P
P
Q
E
Site 35
S313
L
R
F
S
D
S
T
S
K
T
P
P
Q
E
E
Site 36
T315
F
S
D
S
T
S
K
T
P
P
Q
E
E
L
P
Site 37
T323
P
P
Q
E
E
L
P
T
R
V
S
S
P
V
F
Site 38
S326
E
E
L
P
T
R
V
S
S
P
V
F
G
A
T
Site 39
S327
E
L
P
T
R
V
S
S
P
V
F
G
A
T
S
Site 40
S334
S
P
V
F
G
A
T
S
S
I
K
S
G
L
D
Site 41
S338
G
A
T
S
S
I
K
S
G
L
D
L
N
T
S
Site 42
T344
K
S
G
L
D
L
N
T
S
L
S
P
S
L
L
Site 43
S345
S
G
L
D
L
N
T
S
L
S
P
S
L
L
Q
Site 44
S347
L
D
L
N
T
S
L
S
P
S
L
L
Q
P
G
Site 45
S349
L
N
T
S
L
S
P
S
L
L
Q
P
G
K
K
Site 46
T361
G
K
K
K
H
L
K
T
L
P
F
S
N
T
C
Site 47
S365
H
L
K
T
L
P
F
S
N
T
C
I
S
R
L
Site 48
T367
K
T
L
P
F
S
N
T
C
I
S
R
L
E
K
Site 49
T375
C
I
S
R
L
E
K
T
R
S
K
S
E
D
S
Site 50
S377
S
R
L
E
K
T
R
S
K
S
E
D
S
A
L
Site 51
S379
L
E
K
T
R
S
K
S
E
D
S
A
L
F
T
Site 52
S382
T
R
S
K
S
E
D
S
A
L
F
T
H
H
S
Site 53
T386
S
E
D
S
A
L
F
T
H
H
S
L
G
S
E
Site 54
S389
S
A
L
F
T
H
H
S
L
G
S
E
V
N
K
Site 55
T422
S
L
G
E
Q
N
R
T
E
Y
G
K
D
S
N
Site 56
Y424
G
E
Q
N
R
T
E
Y
G
K
D
S
N
T
D
Site 57
S428
R
T
E
Y
G
K
D
S
N
T
D
K
H
L
E
Site 58
T430
E
Y
G
K
D
S
N
T
D
K
H
L
E
P
L
Site 59
S439
K
H
L
E
P
L
K
S
L
G
G
R
T
S
K
Site 60
S445
K
S
L
G
G
R
T
S
K
R
K
K
T
E
E
Site 61
T450
R
T
S
K
R
K
K
T
E
E
E
S
E
H
E
Site 62
S454
R
K
K
T
E
E
E
S
E
H
E
V
S
C
P
Site 63
S459
E
E
S
E
H
E
V
S
C
P
Q
A
S
F
D
Site 64
S464
E
V
S
C
P
Q
A
S
F
D
K
E
N
A
F
Site 65
S494
M
D
K
P
L
D
L
S
D
R
F
S
A
I
Q
Site 66
S498
L
D
L
S
D
R
F
S
A
I
Q
R
Q
E
K
Site 67
S506
A
I
Q
R
Q
E
K
S
Q
G
S
E
T
S
K
Site 68
S509
R
Q
E
K
S
Q
G
S
E
T
S
K
N
K
F
Site 69
T520
K
N
K
F
R
Q
V
T
L
Y
E
A
L
K
T
Site 70
Y522
K
F
R
Q
V
T
L
Y
E
A
L
K
T
I
P
Site 71
T527
T
L
Y
E
A
L
K
T
I
P
K
G
F
S
S
Site 72
S533
K
T
I
P
K
G
F
S
S
S
R
K
A
S
D
Site 73
S534
T
I
P
K
G
F
S
S
S
R
K
A
S
D
G
Site 74
S535
I
P
K
G
F
S
S
S
R
K
A
S
D
G
N
Site 75
S539
F
S
S
S
R
K
A
S
D
G
N
C
T
L
P
Site 76
S549
N
C
T
L
P
K
D
S
P
G
E
P
C
S
Q
Site 77
S555
D
S
P
G
E
P
C
S
Q
E
C
I
I
L
Q
Site 78
S568
L
Q
P
L
N
K
C
S
P
D
N
K
P
S
L
Site 79
S574
C
S
P
D
N
K
P
S
L
Q
I
K
E
E
N
Site 80
S593
I
P
L
R
P
R
E
S
L
E
T
E
N
V
L
Site 81
T596
R
P
R
E
S
L
E
T
E
N
V
L
D
D
I
Site 82
S605
N
V
L
D
D
I
K
S
A
G
S
H
E
P
I
Site 83
S618
P
I
K
I
Q
T
R
S
D
H
G
G
C
E
L
Site 84
S641
C
R
T
G
K
I
K
S
L
Q
N
N
Q
D
V
Site 85
S656
S
F
E
N
I
Q
W
S
I
D
P
G
A
D
L
Site 86
S664
I
D
P
G
A
D
L
S
Q
Y
K
M
D
V
T
Site 87
Y666
P
G
A
D
L
S
Q
Y
K
M
D
V
T
V
I
Site 88
T671
S
Q
Y
K
M
D
V
T
V
I
D
T
K
D
G
Site 89
T675
M
D
V
T
V
I
D
T
K
D
G
S
Q
S
K
Site 90
S679
V
I
D
T
K
D
G
S
Q
S
K
L
G
G
E
Site 91
S713
Q
E
Q
K
G
E
K
S
S
N
E
E
R
K
M
Site 92
S723
E
E
R
K
M
N
D
S
L
E
D
M
F
D
R
Site 93
T731
L
E
D
M
F
D
R
T
T
H
E
E
Y
E
S
Site 94
T732
E
D
M
F
D
R
T
T
H
E
E
Y
E
S
C
Site 95
S738
T
T
H
E
E
Y
E
S
C
L
A
D
S
F
S
Site 96
S743
Y
E
S
C
L
A
D
S
F
S
Q
A
A
D
E
Site 97
S745
S
C
L
A
D
S
F
S
Q
A
A
D
E
E
E
Site 98
S755
A
D
E
E
E
E
L
S
T
A
T
K
K
L
H
Site 99
T756
D
E
E
E
E
L
S
T
A
T
K
K
L
H
T
Site 100
Y780
Q
K
A
F
V
E
P
Y
F
K
G
D
E
R
E
Site 101
T788
F
K
G
D
E
R
E
T
S
L
Q
N
F
P
H
Site 102
S789
K
G
D
E
R
E
T
S
L
Q
N
F
P
H
I
Site 103
Y819
T
C
K
E
C
E
I
Y
Y
A
D
M
P
A
E
Site 104
S834
E
R
E
K
K
L
A
S
C
S
R
H
R
F
R
Site 105
S836
E
K
K
L
A
S
C
S
R
H
R
F
R
Y
I
Site 106
Y842
C
S
R
H
R
F
R
Y
I
P
P
N
T
P
E
Site 107
T847
F
R
Y
I
P
P
N
T
P
E
N
F
W
E
V
Site 108
Y867
Q
T
C
M
E
R
G
Y
I
K
E
D
L
D
P
Site 109
Y884
R
P
K
R
R
Q
P
Y
N
A
I
F
S
P
K
Site 110
S889
Q
P
Y
N
A
I
F
S
P
K
G
K
E
Q
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation