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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BARD1
Full Name:
BRCA1-associated RING domain protein 1
Alias:
Type:
Mass (Da):
86648
Number AA:
777
UniProt ID:
Q99728
International Prot ID:
IPI00017746
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0070531
GO:0031436
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0019900
GO:0046982
PhosphoSite+
KinaseNET
Biological Process:
GO:0006281
GO:0007050
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
N
R
Q
P
R
I
R
S
G
N
E
P
R
S
A
Site 2
S22
R
S
G
N
E
P
R
S
A
P
A
M
E
P
D
Site 3
S51
L
E
K
L
L
R
C
S
R
C
T
N
I
L
R
Site 4
S103
K
I
N
R
Q
L
D
S
M
I
Q
L
C
S
K
Site 5
S121
L
L
H
D
N
E
L
S
D
L
K
E
D
K
P
Site 6
S131
K
E
D
K
P
R
K
S
L
F
N
D
A
G
N
Site 7
S148
N
S
I
K
M
W
F
S
P
R
S
K
K
V
R
Site 8
Y156
P
R
S
K
K
V
R
Y
V
V
S
K
A
S
V
Site 9
S179
D
A
S
A
Q
Q
D
S
Y
E
F
V
S
P
S
Site 10
Y180
A
S
A
Q
Q
D
S
Y
E
F
V
S
P
S
P
Site 11
S184
Q
D
S
Y
E
F
V
S
P
S
P
P
A
D
V
Site 12
S186
S
Y
E
F
V
S
P
S
P
P
A
D
V
S
E
Site 13
S192
P
S
P
P
A
D
V
S
E
R
A
K
K
A
S
Site 14
S199
S
E
R
A
K
K
A
S
A
R
S
G
K
K
Q
Site 15
T210
G
K
K
Q
K
K
K
T
L
A
E
I
N
Q
K
Site 16
S231
K
E
D
G
E
F
D
S
K
E
E
S
K
Q
K
Site 17
S235
E
F
D
S
K
E
E
S
K
Q
K
L
V
S
F
Site 18
S241
E
S
K
Q
K
L
V
S
F
C
S
Q
P
S
V
Site 19
S244
Q
K
L
V
S
F
C
S
Q
P
S
V
I
S
S
Site 20
S251
S
Q
P
S
V
I
S
S
P
Q
I
N
G
E
I
Site 21
S263
G
E
I
D
L
L
A
S
G
S
L
T
E
S
E
Site 22
S269
A
S
G
S
L
T
E
S
E
C
F
G
S
L
T
Site 23
S274
T
E
S
E
C
F
G
S
L
T
E
V
S
L
P
Site 24
S288
P
L
A
E
Q
I
E
S
P
D
T
K
S
R
N
Site 25
T291
E
Q
I
E
S
P
D
T
K
S
R
N
E
V
V
Site 26
S293
I
E
S
P
D
T
K
S
R
N
E
V
V
T
P
Site 27
T299
K
S
R
N
E
V
V
T
P
E
K
V
C
K
N
Site 28
Y307
P
E
K
V
C
K
N
Y
L
T
S
K
K
S
L
Site 29
T309
K
V
C
K
N
Y
L
T
S
K
K
S
L
P
L
Site 30
S313
N
Y
L
T
S
K
K
S
L
P
L
E
N
N
G
Site 31
S329
R
G
H
H
N
R
L
S
S
P
I
S
K
R
C
Site 32
S330
G
H
H
N
R
L
S
S
P
I
S
K
R
C
R
Site 33
S333
N
R
L
S
S
P
I
S
K
R
C
R
T
S
I
Site 34
T338
P
I
S
K
R
C
R
T
S
I
L
S
T
S
G
Site 35
S339
I
S
K
R
C
R
T
S
I
L
S
T
S
G
D
Site 36
S342
R
C
R
T
S
I
L
S
T
S
G
D
F
V
K
Site 37
T343
C
R
T
S
I
L
S
T
S
G
D
F
V
K
Q
Site 38
T351
S
G
D
F
V
K
Q
T
V
P
S
E
N
I
P
Site 39
S363
N
I
P
L
P
E
C
S
S
P
P
S
C
K
R
Site 40
S364
I
P
L
P
E
C
S
S
P
P
S
C
K
R
K
Site 41
S367
P
E
C
S
S
P
P
S
C
K
R
K
V
G
G
Site 42
T375
C
K
R
K
V
G
G
T
S
G
R
K
N
S
N
Site 43
S376
K
R
K
V
G
G
T
S
G
R
K
N
S
N
M
Site 44
S381
G
T
S
G
R
K
N
S
N
M
S
D
E
F
I
Site 45
S384
G
R
K
N
S
N
M
S
D
E
F
I
S
L
S
Site 46
S389
N
M
S
D
E
F
I
S
L
S
P
G
T
P
P
Site 47
S391
S
D
E
F
I
S
L
S
P
G
T
P
P
S
T
Site 48
T394
F
I
S
L
S
P
G
T
P
P
S
T
L
S
S
Site 49
S397
L
S
P
G
T
P
P
S
T
L
S
S
S
S
Y
Site 50
T398
S
P
G
T
P
P
S
T
L
S
S
S
S
Y
R
Site 51
S400
G
T
P
P
S
T
L
S
S
S
S
Y
R
R
V
Site 52
S401
T
P
P
S
T
L
S
S
S
S
Y
R
R
V
M
Site 53
S402
P
P
S
T
L
S
S
S
S
Y
R
R
V
M
S
Site 54
S403
P
S
T
L
S
S
S
S
Y
R
R
V
M
S
S
Site 55
Y404
S
T
L
S
S
S
S
Y
R
R
V
M
S
S
P
Site 56
S409
S
S
Y
R
R
V
M
S
S
P
S
A
M
K
L
Site 57
S410
S
Y
R
R
V
M
S
S
P
S
A
M
K
L
L
Site 58
S412
R
R
V
M
S
S
P
S
A
M
K
L
L
P
N
Site 59
T430
K
R
N
H
R
G
E
T
L
L
H
I
A
S
I
Site 60
S443
S
I
K
G
D
I
P
S
V
E
Y
L
L
Q
N
Site 61
Y446
G
D
I
P
S
V
E
Y
L
L
Q
N
G
S
D
Site 62
S452
E
Y
L
L
Q
N
G
S
D
P
N
V
K
D
H
Site 63
Y492
A
L
V
N
T
T
G
Y
Q
N
D
S
P
L
H
Site 64
S496
T
T
G
Y
Q
N
D
S
P
L
H
D
A
A
K
Site 65
Y533
F
G
L
R
P
V
D
Y
T
D
D
E
S
M
K
Site 66
T534
G
L
R
P
V
D
Y
T
D
D
E
S
M
K
S
Site 67
S538
V
D
Y
T
D
D
E
S
M
K
S
L
L
L
L
Site 68
S541
T
D
D
E
S
M
K
S
L
L
L
L
P
E
K
Site 69
S551
L
L
P
E
K
N
E
S
S
S
A
S
H
C
S
Site 70
S552
L
P
E
K
N
E
S
S
S
A
S
H
C
S
V
Site 71
S553
P
E
K
N
E
S
S
S
A
S
H
C
S
V
M
Site 72
S555
K
N
E
S
S
S
A
S
H
C
S
V
M
N
T
Site 73
S558
S
S
S
A
S
H
C
S
V
M
N
T
G
Q
R
Site 74
T562
S
H
C
S
V
M
N
T
G
Q
R
R
D
G
P
Site 75
S579
L
I
G
S
G
L
S
S
E
Q
Q
K
M
L
S
Site 76
S586
S
E
Q
Q
K
M
L
S
E
L
A
V
I
L
K
Site 77
Y597
V
I
L
K
A
K
K
Y
T
E
F
D
S
T
V
Site 78
S602
K
K
Y
T
E
F
D
S
T
V
T
H
V
V
V
Site 79
T603
K
Y
T
E
F
D
S
T
V
T
H
V
V
V
P
Site 80
Y651
V
C
E
Q
E
E
K
Y
E
I
P
E
G
P
R
Site 81
S660
I
P
E
G
P
R
R
S
R
L
N
R
E
Q
L
Site 82
S704
A
G
G
G
Q
I
L
S
R
K
P
K
P
D
S
Site 83
S711
S
R
K
P
K
P
D
S
D
V
T
Q
T
I
N
Site 84
T714
P
K
P
D
S
D
V
T
Q
T
I
N
T
V
A
Site 85
T719
D
V
T
Q
T
I
N
T
V
A
Y
H
A
R
P
Site 86
S728
A
Y
H
A
R
P
D
S
D
Q
R
F
C
T
Q
Site 87
T734
D
S
D
Q
R
F
C
T
Q
Y
I
I
Y
E
D
Site 88
Y736
D
Q
R
F
C
T
Q
Y
I
I
Y
E
D
L
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation