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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LITAF
Full Name:
Lipopolysaccharide-induced tumor necrosis factor-alpha factor
Alias:
FLJ38636; Lipopolysaccharide-induced TNF factor; LPS-induced TNF-alpha factor; P53-induced protein 7; PIG7; SIMPLE; Small integral membrane protein of lysosome/late endosome; TP53I7
Type:
Transcription factor
Mass (Da):
17107
Number AA:
161
UniProt ID:
Q99732
International Prot ID:
IPI00645256
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005813
GO:0043231
Uniprot
OncoNet
Molecular Function:
GO:0003702
GO:0050699
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0043123
GO:0006357
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
P
G
P
Y
Q
A
A
T
G
P
S
S
A
P
S
Site 2
S14
Y
Q
A
A
T
G
P
S
S
A
P
S
A
P
P
Site 3
S15
Q
A
A
T
G
P
S
S
A
P
S
A
P
P
S
Site 4
S18
T
G
P
S
S
A
P
S
A
P
P
S
Y
E
E
Site 5
S22
S
A
P
S
A
P
P
S
Y
E
E
T
V
A
V
Site 6
Y23
A
P
S
A
P
P
S
Y
E
E
T
V
A
V
N
Site 7
T26
A
P
P
S
Y
E
E
T
V
A
V
N
S
Y
Y
Site 8
S31
E
E
T
V
A
V
N
S
Y
Y
P
T
P
P
A
Site 9
Y32
E
T
V
A
V
N
S
Y
Y
P
T
P
P
A
P
Site 10
Y33
T
V
A
V
N
S
Y
Y
P
T
P
P
A
P
M
Site 11
T35
A
V
N
S
Y
Y
P
T
P
P
A
P
M
P
G
Site 12
T45
A
P
M
P
G
P
T
T
G
L
V
T
G
P
D
Site 13
S60
G
K
G
M
N
P
P
S
Y
Y
T
Q
P
A
P
Site 14
Y61
K
G
M
N
P
P
S
Y
Y
T
Q
P
A
P
I
Site 15
Y62
G
M
N
P
P
S
Y
Y
T
Q
P
A
P
I
P
Site 16
T63
M
N
P
P
S
Y
Y
T
Q
P
A
P
I
P
N
Site 17
T75
I
P
N
N
N
P
I
T
V
Q
T
V
Y
V
Q
Site 18
S105
S
C
N
K
M
I
V
S
Q
L
S
Y
N
A
G
Site 19
Y147
A
L
Q
D
V
D
H
Y
C
P
N
C
R
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation