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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NPAS1
Full Name:
Neuronal PAS domain-containing protein 1
Alias:
Basic-helix-loop-helix-PAS protein MOP5;Class E basic helix-loop-helix protein 11;Member of PAS protein 5;PAS domain-containing protein 5
Type:
Mass (Da):
62702
Number AA:
590
UniProt ID:
Q99742
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
A
P
Y
P
G
S
G
G
G
S
E
V
K
Site 2
S12
Y
P
G
S
G
G
G
S
E
V
K
C
V
G
G
Site 3
S50
Q
A
Q
R
K
E
K
S
R
N
A
A
R
S
R
Site 4
S56
K
S
R
N
A
A
R
S
R
R
G
K
E
N
L
Site 5
S79
L
P
L
P
G
A
I
S
S
Q
L
D
K
A
S
Site 6
S86
S
S
Q
L
D
K
A
S
I
V
R
L
S
V
T
Site 7
Y161
N
Q
E
G
K
F
L
Y
I
S
E
T
V
S
I
Site 8
S180
S
Q
V
E
M
T
G
S
S
V
F
D
Y
I
H
Site 9
Y185
T
G
S
S
V
F
D
Y
I
H
P
G
D
H
S
Site 10
S192
Y
I
H
P
G
D
H
S
E
V
L
E
Q
L
G
Site 11
T202
L
E
Q
L
G
L
R
T
P
T
P
G
P
P
T
Site 12
T204
Q
L
G
L
R
T
P
T
P
G
P
P
T
P
P
Site 13
T209
T
P
T
P
G
P
P
T
P
P
S
V
S
S
S
Site 14
S212
P
G
P
P
T
P
P
S
V
S
S
S
S
S
S
Site 15
S214
P
P
T
P
P
S
V
S
S
S
S
S
S
S
S
Site 16
S215
P
T
P
P
S
V
S
S
S
S
S
S
S
S
S
Site 17
S216
T
P
P
S
V
S
S
S
S
S
S
S
S
S
L
Site 18
S217
P
P
S
V
S
S
S
S
S
S
S
S
S
L
A
Site 19
S218
P
S
V
S
S
S
S
S
S
S
S
S
L
A
D
Site 20
S219
S
V
S
S
S
S
S
S
S
S
S
L
A
D
T
Site 21
S220
V
S
S
S
S
S
S
S
S
S
L
A
D
T
P
Site 22
S221
S
S
S
S
S
S
S
S
S
L
A
D
T
P
E
Site 23
S222
S
S
S
S
S
S
S
S
L
A
D
T
P
E
I
Site 24
T226
S
S
S
S
L
A
D
T
P
E
I
E
A
S
L
Site 25
S232
D
T
P
E
I
E
A
S
L
T
K
V
P
P
S
Site 26
T234
P
E
I
E
A
S
L
T
K
V
P
P
S
S
L
Site 27
S239
S
L
T
K
V
P
P
S
S
L
V
Q
E
R
S
Site 28
S240
L
T
K
V
P
P
S
S
L
V
Q
E
R
S
F
Site 29
S246
S
S
L
V
Q
E
R
S
F
F
V
R
M
K
S
Site 30
S253
S
F
F
V
R
M
K
S
T
L
T
K
R
G
L
Site 31
T256
V
R
M
K
S
T
L
T
K
R
G
L
H
V
K
Site 32
S265
R
G
L
H
V
K
A
S
G
Y
K
V
I
H
V
Site 33
T273
G
Y
K
V
I
H
V
T
G
R
L
R
A
H
A
Site 34
S323
L
A
C
E
S
R
V
S
D
H
M
D
L
G
P
Site 35
S331
D
H
M
D
L
G
P
S
E
L
V
G
R
S
C
Site 36
S337
P
S
E
L
V
G
R
S
C
Y
Q
F
V
H
G
Site 37
Y339
E
L
V
G
R
S
C
Y
Q
F
V
H
G
Q
D
Site 38
T348
F
V
H
G
Q
D
A
T
R
I
R
Q
S
H
V
Site 39
S353
D
A
T
R
I
R
Q
S
H
V
D
L
L
D
K
Site 40
Y367
K
G
Q
V
M
T
G
Y
Y
R
W
L
Q
R
A
Site 41
S389
S
V
A
T
V
A
G
S
G
K
S
P
G
E
H
Site 42
S392
T
V
A
G
S
G
K
S
P
G
E
H
H
V
L
Site 43
S406
L
W
V
S
H
V
L
S
Q
A
E
G
G
Q
T
Site 44
T413
S
Q
A
E
G
G
Q
T
P
L
D
A
F
Q
L
Site 45
S431
V
A
C
E
E
A
S
S
P
G
P
E
P
T
E
Site 46
T437
S
S
P
G
P
E
P
T
E
P
E
P
P
T
E
Site 47
T458
A
E
N
E
A
P
Q
T
Q
G
K
R
I
K
V
Site 48
T472
V
E
P
G
P
R
E
T
K
G
S
E
D
S
G
Site 49
S475
G
P
R
E
T
K
G
S
E
D
S
G
D
E
D
Site 50
S478
E
T
K
G
S
E
D
S
G
D
E
D
P
S
S
Site 51
S484
D
S
G
D
E
D
P
S
S
H
P
A
T
P
R
Site 52
S485
S
G
D
E
D
P
S
S
H
P
A
T
P
R
P
Site 53
T489
D
P
S
S
H
P
A
T
P
R
P
E
F
T
S
Site 54
T522
P
P
G
D
P
P
P
T
L
L
H
A
G
F
L
Site 55
T541
R
G
L
C
T
P
G
T
I
R
Y
G
P
A
E
Site 56
Y577
Y
P
P
L
G
L
P
Y
P
G
P
A
G
T
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation